Posaconazole Administration in Hospitalized Children in the United States

2018 ◽  
Vol 8 (5) ◽  
pp. 481-484
Author(s):  
Sondra Lavigne ◽  
Brian T Fisher ◽  
Darcy Ellis ◽  
Theoklis E Zaoutis ◽  
Kevin J Downes
Keyword(s):  
United States ◽  
Information System ◽  
Health Information ◽  
Health Information System ◽  
The United States ◽  
Hospitalized Children ◽  
Pediatric Health ◽  
System A ◽  
Using Data

Abstract In this study, we evaluated posaconazole use among hospitalized children between October 2006 and September 2015 using data from the Pediatric Health Information System. A total of 878 children (in 1949 admissions) received posaconazole, and administration increased 22% per year overall and 27% per year in children aged <13 years for whom the drug was not approved.

scholarly journals Complications and Cost of Syndactyly Reconstruction in the United States: Analysis of the Pediatric Health Information System

Hand ◽  
2016 ◽  
Vol 12 (4) ◽  
pp. 327-334 ◽  
Author(s):  
Maria F. Canizares ◽  
Lanna Feldman ◽  
Patricia E. Miller ◽  
Peter M. Waters ◽  
Donald S. Bae
Keyword(s):  
United States ◽  
Information System ◽  
Health Information ◽  
Orthopedic Surgery ◽  
Complication Rate ◽  
Health Information System ◽  
The United States ◽  
Pediatric Health ◽  
Pediatric Hospitals ◽  
Pediatric Orthopedic

Background: Syndactyly is one of the most common congenital differences of the upper extremity and offers an exceptional opportunity to evaluate value-based care in pediatric orthopedic surgery. We designed a study to characterize complications and cost associated to syndactyly surgery among US pediatric hospitals. Methods: A total of 2047 patients were identified for syndactyly surgery at 38 pediatric hospitals from 2009 to 2012 using the Pediatric Health Information System (PHIS) database. We examined costs as well as complication rates across hospitals stratified by patient and hospital variables. Results: The postoperative complication rate was 1.9% (95% confidence interval [CI]: 1.3%-2.5%). Postoperative infection rate was 1.6% and surgical complication rate was 0.3%. Median adjusted standardized cost was $4112.5 (interquartile range: $2979-$6049). Patients with more than 1 diagnosis had 19 times higher risk of complications and were associated with 13% more hospital cost than those with syndactyly as single diagnosis ( P < .001). Finally, there was a wide variation in cost across hospitals; 8 (21%) yielded confidence limits above the benchmarked value. Conclusions: In the United States, it is important to recognize variations in practice of syndactyly surgery in hopes of developing quality improvement strategies in pediatric orthopedic surgery.

National efforts to improve health information system safety in Canada, the United States of America and England

2013 ◽  
Vol 82 (5) ◽  
pp. e149-e160 ◽  
Author(s):  
Andre W. Kushniruk ◽  
David W. Bates ◽  
Michael Bainbridge ◽  
Mowafa S. Househ ◽  
Elizabeth M. Borycki
Keyword(s):  
United States ◽  
Information System ◽  
Health Information ◽  
United States Of America ◽  
Health Information System ◽  
The United States ◽  
System Safety ◽  
Improve Health

Impact of Perioperative Tachydysrhythmias on Mortality and Length of Stay in Complete Repair of Tetralogy of Fallot: A Multicenter Retrospective Cohort Study from the Pediatric Health Information System

Cardiology ◽  
2021 ◽  
pp. 1-7
Author(s):  
Aziez Ahmed ◽  
Parthak Prodhan ◽  
Beverly J. Spray ◽  
Elijah H. Bolin
Keyword(s):  
Information System ◽  
Length Of Stay ◽  
Health Information ◽  
Tetralogy Of Fallot ◽  
Health Information System ◽  
Inpatient Mortality ◽  
Pediatric Health ◽  
Mortality And Morbidity ◽  
Multiple Risk Factors ◽  
Complete Repair

Introduction: Tachydysrhythmias (TDS) frequently occur after complete repair of tetralogy of Fallot (TOF). However, not much is known about the effect of TDS on morbidity and mortality after TOF repair. We sought to assess the associations between TDS and mortality and morbidity after repair of TOF using a multicentre database. Materials and Methods: We identified all children aged 0–5 years in the Pediatric Health Information System who underwent TOF repair between 2004 and 2015. Codes for TDS were used to identify cases. Outcome variables were inpatient mortality and total length of stay (LOS). Univariate and multiple logistic and linear regression analyses were used to identify the effects of multiple risk factors, including TDS, on mortality and LOS. Results: A total of 7,749 patients met inclusion criteria, of which 1,493 (19%) had codes for TDS. There was no association between TDS and inpatient mortality. However, TDS were associated with 1.1 days longer LOS and accounted for 2% of the variation observed in LOS. Conclusion: After complete repair of TOF, TDS were not associated with mortality and appeared to have only a modest effect on LOS.

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