Radical Prostatectomy Versus Observation in Early Prostate Cancer

Author(s):  
Philipp Dahm

This chapter provides a summary of the landmark Scandinavian Prostate Cancer Group Study Number 4 trial of men with clinically localized prostate cancer from the pre–prostate-specific antigen (PSA) era who were randomized to radical prostatectomy versus watchful waiting and were followed long term. With follow-up of more than 20 years, the results favored surgery with regard to prostate cancer mortality.

2009 ◽  
Vol 75 (5) ◽  
pp. 1350-1356 ◽  
Author(s):  
Michael J. Zelefsky ◽  
Weiji Shi ◽  
Yoshiya Yamada ◽  
Marisa A. Kollmeier ◽  
Brett Cox ◽  
...  

2005 ◽  
Vol 173 (4S) ◽  
pp. 146-146
Author(s):  
Georg C. Bartsch ◽  
Wolfgang Horninger ◽  
Wilhelm Oberaigner ◽  
Dieter Schönitzer ◽  
Helmut Klocker ◽  
...  

Author(s):  
Philipp Dahm

This chapter provides a summary of the landmark PIVOT trial that randomized men with clinically localized prostate cancer from the early prostate-specific antigen (PSA) era to radical prostatectomy versus watchful waiting. Based on long-term follow-up, the study found that surgery provided only small reductions in disease-specific survival but caused substantial side effects. It suggested that many men with clinically localized prostate cancer fare well with watchful waiting.


2015 ◽  
Vol 33 (1) ◽  
pp. 16.e1-16.e7 ◽  
Author(s):  
Heikki Seikkula ◽  
Kari T. Syvänen ◽  
Samu Kurki ◽  
Tuomas Mirtti ◽  
Pekka Taimen ◽  
...  

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