Migraine

Author(s):  
Richard Peatfield ◽  
Fumihiko Sakai

The vast majority of patients presenting with headache and no physical signs will have migraine, or, less commonly, a variant such as cluster headache. Some migraine patients will have a typical visual, sensory, or speech aura, while others will have less clear-cut premonitory symptoms. A careful history will establish whether there are any atypical features that might warrant further investigation and/or suggest an alternative diagnosis. It is essential that the initial assessment ascertains the frequency and severity of the attacks, as this will determine whether analgesic or prophylactic treatment or both should be offered. The patient’s previous medication should be recorded, noting the largest doses given and the reason why each had been discontinued. Many will be overusing analgesics, particularly opiates, and these can easily lead directly to a chronic drug-induced headache. The real skill in headache management is ensuring that the patient’s history is fully and accurately recorded.

Cephalalgia ◽  
1998 ◽  
Vol 18 (4) ◽  
pp. 216-221 ◽  
Author(s):  
S Evers ◽  
H Voss ◽  
B Bauer ◽  
P Sörös ◽  
I-W Husstedt

Autonomic functions of different primary headache types have been investigated in several studies, most of them analyzing cardiovascular reflex mechanisms or biochemical changes. The results are contradictory; only in tension-type headache and in cluster headache has a sympathetic hypofunction been shown in a preponderance of studies. We analyzed the peripheral autonomous potentials (PAPs) in different primary headache types and in drug-induced headache and compared the results with those of healthy subjects and of patients with low back pain. Latencies of PAPs were significantly increased in all headache types but not in low back pain; amplitudes of PAPs did not show significant differences compared to healthy subjects. Patients with a long duration of drug abuse had increased PAP latencies, whereas patients with a high number of migraine attacks per year had decreased latencies. Our data suggest that sympathetic hypo-function as measured by PAP latencies is a general phenomenon in headache but not in all pain syndromes. Drug abuse leads to an increase of this hypofunction. While measuring PAPs is not an appropriate method by which to differentiate between headache disorders, it allows assessment of autonomic disturbances in primary and drug-induced headache.


Cephalalgia ◽  
2004 ◽  
Vol 24 (9) ◽  
pp. 753-757 ◽  
Author(s):  
T Sprenger ◽  
M Valet ◽  
M Hammes ◽  
P Erhard ◽  
A Berthele ◽  
...  

We report headache induced BOLD changes in an atypical case of trigeminal autonomic cephalgia (TAC). A 68-year-old patient was imaged using fMRi during three attacks of a periorbital head-pain with a average duration of 3 min. During the attacks, left sided conjunctival injection, rhinorrhea, lacrimation, facial sweating and hypersalivation were apparent. These attacks were usually partly responsive to oxygen administration but otherwise refractory to any drug. The patient described either attacks with a duration of one minute or less or longer attacks persisting for maximum of 20 min with headaches occurring up to 100 times a day. When considering the symptoms, frequency, duration and therapeutic response of the patient's headache, no clear-cut classification to one of the subtypes of trigeminal autonomic cephalgias (cluster headache, paroxysmal hemicrania, SUNCT) or trigeminal neuralgia was possible. The cerebral activation pattern was similar but not identical to those previously observed in cluster headache and SUNCT with a prominent activation in the hypothalamic grey matter. This case study underlines the conceptual value of the term TAC for the group of headaches focusing around the trigeminal-autonomic reflex. Our results emphasize the importance of the hypothalamus as key region in the pathophysiology of this entity.


1999 ◽  
Vol 246 (9) ◽  
pp. 802-809 ◽  
Author(s):  
S. Evers ◽  
Birgit Suhr ◽  
Birgit Bauer ◽  
Karl-Heinz Grotemeyer ◽  
Ingo-W. Husstedt

2020 ◽  
Vol 26 (1) ◽  
pp. 28-32
Author(s):  
Lidiya D. Sadretdinova ◽  
Khristina P. Derevyanko

Drug-induced headache (DIH) is one of the most common forms of chronic headache (CH). Management of patients with DIH remains a pressing problem of modern medicine. This condition is characterized by headache over 15 days a month for more than 3 months. On the basis of the BSMU Clinic, we assessed the health status of young people with DIH and nicotine addiction. Patients with nicotine addiction were evaluated for the degree of negative effect of smoking on respiratory function. It was found that the majority of patients took monocomponent analgesics, and the minority of patients took combined analgesics and triptans; compared with young men, young women were less likely to seek medical advice if the episodes of headache became more frequent; however, uncontrolled use of painkillers was observed more often in males. In the absence of an analgesic effect 30 h after medication intake, young men repeated the medication in 60% of cases. Educational programs about DIH and the development of CHs with associated nicotine addiction may play an important in preventing the development of the condition.


Cephalalgia ◽  
1998 ◽  
Vol 18 (2) ◽  
pp. 91-93 ◽  
Author(s):  
JN Blau ◽  
HO Engel

Warning symptoms in 150 cluster headache patients were studied by focusing on attacks occurring during waking hours. Warnings were divided into prodromes that started minutes before the pain of individual attacks (122 patients) and premonitory symptoms preceding the onset of cluster periods by days to weeks (12 patients). Pathogenetic and therapeutic implications are discussed.


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