Intracerebral haemorrhage in older people
Chapter 10 refers to ‘Intracerebral haemorrhage in older people’. The chapter has been written by the investigators of the TICH-2 trial, one of the largest trial of intracerebral haemorrhage in the world. The authors review the aetiology, epidemiology, risk factors and in particular the causes of intracerebral haemorrhage in older people (including hypertensive arteriopathy, cerebral amyloid angiopathy, cerebral small vessel disease, anticoagulant-related bleeds, haemorrhagic transformation of infarcts). Less common causes such as haemorrhagic brain metastasis, cortical vein thrombosis, arteriovenous malformation, cavernomas, dural arteriovenous fistulas, aneurysms, and septic or mycotic aneurysms are also discussed. Evolution of neuroimaging patterns after a bleed, approach to investigations and management are discussed in detail, in addition to important trial evidence.