Renal transplantation

2021 ◽  
pp. 689-740
Keyword(s):  
Kidney Transplantation ◽  
Renal Transplantation ◽  
Surgical Procedure ◽  
Long Term Outcomes ◽  
Chronic Graft Dysfunction ◽  
Short And Long Term ◽  
Stage Renal Disease ◽  
End Stage ◽  
Work Up

Kidney transplantation is the optimal treatment for end stage renal disease. However, there are risks both from early complications directly related to the surgical procedure, and from longer-term complications resulting from the effects of immunosuppression. This chapter describes the transplant process from the evaluation of patients with renal failure for suitability for transplantation, through the surgical procedure itself, the early and late management of recipients, and the management of the complications that can arise, including acute and chronic graft dysfunction, infection, malignancy, and cardiovascular disease. It also covers the short- and long-term outcomes of kidney transplantation. Since live kidney donors have become an increasingly important source of kidneys for renal transplantation, it also describes the work-up process for potential live donors and the long-term outcomes following donation. Finally, combined kidney/pancreas transplantation is included separately and includes a discussion around the selection and evaluation recipients, the surgical procedure, short- and long-term complications, and the outcomes.

scholarly journals SHORT AND LONG-TERM OUTCOMES OF DIFFERENT REVASCULARIZATION STRATEGIES IN PATIENTS WITH END STAGE RENAL DISEASE ON HEMODIALYSIS

2012 ◽  
Vol 59 (13) ◽  
pp. E549 ◽  
Author(s):  
Abel E. Moreyra ◽  
Peter Hynes ◽  
Yingzi Deng ◽  
Nora M. Cosgrove ◽  
Christopher Brown ◽  
...  
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Long Term Outcomes ◽  
Short And Long Term ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Evaluation of long-term outcomes of deceased donor renal transplantation in patients with end-stage renal disease

2019 ◽  
Vol 8 (2) ◽  
pp. 29-29
Author(s):  
Jaiju James Chakola ◽  
Varun Mamidi ◽  
Vamsi Krishna Makkena ◽  
Jayakumar Matcha ◽  
Ramprasad Elumalai
Keyword(s):  
Renal Transplantation ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Deceased Donor ◽  
Long Term Outcomes ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Effects of renal transplantation on erectile dysfunction: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Irham Arif Rahman ◽  
Nur Rasyid ◽  
Ponco Birowo ◽  
Widi Atmoko
Keyword(s):  
Systematic Review ◽  
Erectile Dysfunction ◽  
Kidney Transplantation ◽  
Renal Transplantation ◽  
End Stage Renal Disease ◽  
Erectile Function ◽  
Meta Analysis ◽  
Post Transplantation ◽  
Stage Renal Disease ◽  
End Stage

AbstractErectile dysfunction (ED) is a major global health burden commonly observed in patients with end-stage renal disease (ESRD). Although renal transplantation improves the problem in some patients, it persists in ≈20–50% of recipients. Studies regarding the effects of kidney transplantation on ED present contradictory findings. We performed a systematic review to summarise the effects of kidney transplantation on ED. A systematic literature search was performed across PubMed, Cochrane, and Scopus databases in April 2020. We included all prospective studies that investigated the pre and posttransplant international index of erectile function (IIEF-5) scores in recipients with ED. Data search in PubMed and Google Scholar produced 1326 articles; eight were systematically reviewed with a total of 448 subjects. Meta-analysis of IIEF-5 scores showed significant improvements between pre and post transplantation. Our findings confirm that renal transplantation improves erectile function. Furthermore, transplantation also increases testosterone level. However, the evidence is limited because of the small number of studies. Further studies are required to investigate the effects of renal transplantation on erectile function.

Long-Term Outcomes of Drug-Eluting Stents Versus Bare-Metal Stents in End-Stage Renal Disease Patients on Dialysis

2018 ◽  
Vol 26 (6) ◽  
pp. 277-286 ◽  
Author(s):  
Sahil Khera ◽  
Pedro A. Villablanca ◽  
Dhaval Kolte ◽  
Tanush Gupta ◽  
Mohammed Hasan Khan ◽  
...  
Keyword(s):  
End Stage Renal Disease ◽  
Bare Metal Stents ◽  
Drug Eluting Stents ◽  
Metal Stents ◽  
Bare Metal ◽  
Long Term Outcomes ◽  
Drug Eluting ◽  
Stage Renal Disease ◽  
End Stage

P1239SHORT- AND LONG-TERM OUTCOME OF END-STAGE RENAL DISEASE PATIENTS WITH ACUTE MYOCARDIAL INFARCTION

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Hirota Kida ◽  
Shungo Hikoso ◽  
Akihiro Sunaga ◽  
Oeun Bolrathanak ◽  
Takayuki Kojima ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
End Stage Renal Disease ◽  
Term Outcome ◽  
Long Term Outcome ◽  
All Cause Mortality ◽  
Short And Long Term ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Abstract Background and Aims End-stage renal disease (ESRD) patients frequently have the coronary artery disease. However, the short- and long-term outcome of ESRD patients with acute myocardial infarction (AMI) is little known. The aim of this study was to clarify it. Method Using the database of the Osaka Acute Coronary Insufficiency Study (OACIS), 8702 consecutive AMI patients (male: 75.2%, mean age: 66.9±12.2yrs) from 2002 to 2013 were analyzed. We classified these patients into two groups, those with ESRD [ESRD group (n=271)] and without ESRD [No-ESRD group (n=8431)] and examined in-hospital or long-term all-cause mortality. ESRD was defined as eGFR<15ml/min/1.73m2. Results ESRD group had higher frequency of diabetes (59.3% vs 37.8%, p<0.01), hypertension (90.1% vs 63.3%, p<0.01), Killip class≧2 (40.1% vs 21%, p<0.01), multi-vessel disease (69.3% vs 50.8%, p<0.01), and lower frequency of peak CK>3000 (21.7% vs 32.4%, p<0.01) than No-ESRD group. Mean follow-up period was 1041±721 days. In hospital mortality of ESRD group was 27% and No-ESRD group 7.2%. In patients who discharged alive (8027 patients), 1-year mortality of ESRD group was 12.2% and No-ESRD group 3.3%, 3-year mortality of ESRD group was 29.3% and No-ESRD group 8.7%. Kaplan-Meier analysis revealed that the all-cause mortality (log-rank p<0.01) was significantly higher in ESRD group than No-ESRD group. In ESRD patients who discharged alive (203patients), Cox univariate analysis after multiple imputation revealed that peak CK>3000 was significantly associated with an increased risk of mortality (Hazard ratio 2.67, 95% confidence interval 1.18to 6.07, p=0.031). Conclusion In patients with AMI, ESRD was significantly associated with worse short- and long-term outcome, suggesting that careful treatment might be required in ESRD patients with AMI, especially had peak CK>3000.

scholarly journals Long-term outcomes of end-stage renal disease patients admitted to the ICU

2011 ◽  
Vol 26 (9) ◽  
pp. 2965-2970 ◽  
Author(s):  
M. M. Sood ◽  
L. Miller ◽  
P. Komenda ◽  
M. Reslerova ◽  
J. Bueti ◽  
...  
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Long Term Outcomes ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Case Report: Homozygous Pathogenic Variant P209L in the TTC21B Gene: A Rare Cause of End Stage Renal Disease and Biliary Cirrhosis Requiring Combined Liver-Kidney Transplantation. A Case Report and Literature Review

2021 ◽  
Vol 8 ◽  
Author(s):  
Giuseppe Gambino ◽  
Concetta Catalano ◽  
Martina Marangoni ◽  
Caroline Geers ◽  
Alain Le Moine ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Case Report ◽  
Renal Transplantation ◽  
End Stage Renal Disease ◽  
Early Onset ◽  
Unknown Origin ◽  
Pathogenic Variant ◽  
Biliary Cirrhosis ◽  
Stage Renal Disease ◽  
End Stage

Background: Ciliopathies are rare diseases causing renal and extrarenal manifestations. Here, we report the case of a ciliopathy induced by a homozygous pathogenic variant in the TTC21B gene.Case Description: A 47-year-old patient started hemodialysis for chronic kidney disease (CKD) of unknown origin. She presented with early onset of hypertension, pre-eclampsia, myopia and cirrhosis. Renal biopsy showed mild interstitial fibrosis, tubular atrophy, and moderate arteriosclerosis while liver pathology demonstrates grade B biliary cirrhosis. Family history revealed several cases of early-onset severe hypertension and one case of end-stage renal disease (ESRD) needing kidney transplantation at twenty years of age. Clinical exome sequencing showed homozygosis for the pathogenic variant c.626C>T (p.Pro209Leu) in the TTC21B gene. The patient underwent combined liver-renal transplantation with an excellent renal and hepatic graft outcome.Conclusions:TTC21B gene mutations can lead heterogeneous to clinical manifestations and represent an underappreciated cause of ESRD. The paradigm in diagnosis of CKD of early onset and/or of unknown origin is changing and genetic counseling should be performed in all patients and families that meet those criteria. Renal or combined liver-renal transplantation represents the best option for patients suffering from those diseases in terms of prognosis and quality of life.

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