Dermatological emergencies

2010 ◽  
pp. 653-668
Author(s):  
Punit S. Ramrakha ◽  
Kevin P. Moore ◽  
Amir Sam
Keyword(s):  
Herpes Zoster ◽  
Toxic Epidermal Necrolysis ◽  
Pustular Psoriasis ◽  
Drug Reactions ◽  
Eczema Herpeticum ◽  
Bullous Disease ◽  
Autoimmune Bullous Disease ◽  
Generalized Pustular Psoriasis ◽  
Cutaneous Drug Reactions

Cutaneous drug reactions 654 Erythroderma 656 Urticaria 658 Autoimmune bullous disease 660 Eczema herpeticum 662 Herpes zoster 662 Generalized pustular psoriasis 664 Toxic epidermal necrolysis (TEN) 1 666 TEN 2 668 • Maculopapular erythema ± pruritus and scaling. Resolves over 2 weeks when drug is stopped. 46% of cutaneous drug reactions....

Dermatological emergencies

2019 ◽  
pp. 691-710
Author(s):  
Punit S. Ramrakha ◽  
Kevin P. Moore ◽  
Amir H. Sam
Keyword(s):  
Herpes Zoster ◽  
Toxic Epidermal Necrolysis ◽  
Stevens Johnson Syndrome ◽  
Drug Reactions ◽  
Eczema Herpeticum ◽  
Bullous Disease ◽  
Autoimmune Bullous Disease ◽  
Johnson Syndrome ◽  
Generalized Pustular Psoriasis ◽  
Cutaneous Drug Reactions

This chapter discusses dermatological emergencies, including cutaneous drug reactions, erythroderma, urticaria and angio-oedema, autoimmune bullous disease, eczema herpeticum, herpes zoster, generalized pustular psoriasis, and Stevens–Johnson syndrome and toxic epidermal necrolysis.

Two Cases of Generalized Pustular Psoriasis Followed by Acquired Bullous Disease

1999 ◽  
Vol 11 (1) ◽  
pp. 41
Author(s):  
Jae Wang Kim ◽  
Sang Seok Kim ◽  
Kwang Joong Kim ◽  
Jong Min Kim ◽  
Chong Ju Lee ◽  
...  
Keyword(s):  
Pustular Psoriasis ◽  
Bullous Disease ◽  
Generalized Pustular Psoriasis

Development of herpes zoster during infliximab treatment for pediatric generalized pustular psoriasis: A case report

2019 ◽  
Vol 32 (2) ◽  
pp. e12838 ◽  
Author(s):  
Wenjuan Chen ◽  
Chen Peng ◽  
Yangfeng Ding ◽  
Xuemei Yi ◽  
Yunlu Gao
Keyword(s):  
Case Report ◽  
Herpes Zoster ◽  
Pustular Psoriasis ◽  
Infliximab Treatment ◽  
Generalized Pustular Psoriasis

scholarly journals Stevens-Johnson syndrome and toxic epidermal necrolysis: a review

2016 ◽  
Vol 62 (5) ◽  
pp. 468-473 ◽  
Author(s):  
Anthony Wong ◽  
Andrey Augusto Malvestiti ◽  
Mariana de Figueiredo Silva Hafner
Keyword(s):  
High Risk ◽  
Early Diagnosis ◽  
Toxic Epidermal Necrolysis ◽  
Stevens Johnson Syndrome ◽  
Drug Reactions ◽  
Johnson Syndrome ◽  
Life Threatening ◽  
Inflammatory Drugs ◽  
Cutaneous Drug Reactions ◽  
Perilesional Skin

SUMMARY Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are uncommon, acute and potentially life-threatening adverse cutaneous drug reactions. These pathologies are considered a hypersensitivity reaction and can be triggered by drugs, infections and malignancies. The drugs most often involved are allopurinol, some antibiotics, including sulfonamides, anticonvulsants such as carbamazepine, and some non-steroid anti-inflammatory drugs (NSAIDs). Necrosis of keratinocytes is manifested clinically by epidermal detachment, leading to scalded skin appearance. The rash begins on the trunk with subsequent generalization, usually sparing the palmoplantar areas. Macular lesions become purplish, and epidermal detachment occurs, resulting in flaccid blisters that converge and break, resulting in extensive sloughing of necrotic skin. Nikolsky's sign is positive in perilesional skin. SJS and TEN are considered to be two ends of the spectrum of one disease, differing only by their extent of skin detachment. Management of patients with SJS or TEN requires three measures: removal of the offending drug, particularly drugs known to be high-risk; supportive measures and active interventions. Early diagnosis of the disease, recognition of the causal agent and the immediate withdrawal of the drug are the most important actions, as the course of the disease is often rapid and fatal.

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