Choice of surgery for tumour: Staging and surgical margins

2011 ◽  
Author(s):  
Panagiotis D. Gikas ◽  
Timothy W.R. Briggs
Keyword(s):  
Soft Tissue ◽  
Imaging Techniques ◽  
Surgical Margin ◽  
Clinical Staging ◽  
Representative Specimen ◽  
Incisional Biopsy ◽  
Soft Tissue Tumours ◽  
Careful Planning ◽  
Gold Standard Method ◽  
Tumour Biopsy

♦ Bone and soft tissue tumours are rare and should therefore be assessed and treated in specialized centres♦ Clinical staging and pathological grading is used to classify the extent of a tumour♦ Clinical staging uses various imaging techniques, pathological grading requires tumour biopsy following clinical staging♦ The Enneking system is commonly used for surgical staging of bone and soft tissue tumours♦ Surgery is the mainstay of treatment for musculoskeletal tumours♦ The surgical margin describes the extent of the procedure♦ Intralesional margins describe a procedure that removes the tumour alone, radical margins may require removal of entire bone♦ Open incisional biopsy is the gold standard method for obtaining a representative specimen of tumour♦ Careful planning and good collaboration between surgeons, radiologists, and pathologists is crucial to avoid unnecessary or dangerous biopsy procedures.

Inflammatory Myofibroblastic Tumour in Antimesenteric Border of Descending Colon of Children: A Case Report

2015 ◽  
Vol 3 (1) ◽  
pp. 47-50
Author(s):  
Shahnoor Islam ◽  
AKM Amirul Morshed ◽  
Afiqul Islam
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Inflammatory Myofibroblastic Tumour ◽  
Pathological Findings ◽  
Soft Tissue Lesion ◽  
Soft Tissue Tumours ◽  
Inflammatory Pseudotumour ◽  
Erythrocyte Sedimentation ◽  
Antimesenteric Border

Inflammatory myofibroblastic tumour (IMT) occurring at intraabdominal sites in children has rarely been described. Inflammatory pseudotumour is a soft tissue lesion that may be confused with a sarcoma. It is abbreviated as IMT. Inflammatory myofibroblastic tumour, also known as soft tissue tumours, atypical fibromyxoid tumours, pseudosarcomatous fibromyxoid tumour, plasma cell granuloma, pseudosarcomatous myofibrotic proliferation, post-operative spindle cell nodules. In this paper, we describe a case of inflammatory myofibroblastic tumour (IMT) with an unusual constellation of clinical, pathological findings. A 10-year-old girl had an 7-cm intraabdominal mass accompanied by severe anemia, fever, constipation, weight loss, thrombocytosis, elevated erythrocyte sedimentation rate. Laparotomy was performed. The final pathologic diagnosis was IMT. At the most recent follow up (12months) after excision of the tumour, the patient was symptom-free and there was no evidence of tumour recurrence.J. Paediatr. Surg. Bangladesh 3(1): 47-50, 2012 (January)

Non-neurogenic soft tissue tumours of the axilla: Prospective review of 16 cases

1989 ◽  
Vol 42 (2) ◽  
pp. 73-79 ◽  
Author(s):  
R. S. Bell ◽  
J. Ready ◽  
A. Hudson ◽  
B. O'sullivan ◽  
J. Mahoney ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumours

scholarly journals Imaging of Joint and Soft Tissue Involvement in Systemic Lupus Erythematosus

2021 ◽  
Vol 23 (9) ◽  
Author(s):  
Andrea Di Matteo ◽  
Gianluca Smerilli ◽  
Edoardo Cipolletta ◽  
Fausto Salaffi ◽  
Rossella De Angelis ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Soft Tissue ◽  
Lupus Erythematosus ◽  
Structural Damage ◽  
Structural Changes ◽  
Soft Tissues ◽  
Imaging Techniques ◽  
Joint Involvement ◽  
Systemic Lupus ◽  
Muscle Involvement

Abstract Purpose of Review To highlight the potential uses and applications of imaging in the assessment of the most common and relevant musculoskeletal (MSK) manifestations in systemic lupus erythematosus (SLE). Recent Findings Ultrasound (US) and magnetic resonance imaging (MRI) are accurate and sensitive in the assessment of inflammation and structural damage at the joint and soft tissue structures in patients with SLE. The US is particularly helpful for the detection of joint and/or tendon inflammation in patients with arthralgia but without clinical synovitis, and for the early identification of bone erosions. MRI plays a key role in the early diagnosis of osteonecrosis and in the assessment of muscle involvement (i.e., myositis and myopathy). Conventional radiography (CR) remains the traditional gold standard for the evaluation of structural damage in patients with joint involvement, and for the study of bone pathology. The diagnostic value of CR is affected by the poor sensitivity in demonstrating early structural changes at joint and soft tissue level. Computed tomography allows a detailed evaluation of bone damage. However, the inability to distinguish different soft tissues and the need for ionizing radiation limit its use to selected clinical circumstances. Nuclear imaging techniques are valuable resources in patients with suspected bone infection (i.e., osteomyelitis), especially when MRI is contraindicated. Finally, dual energy X-ray absorptiometry represents the imaging mainstay for the assessment and monitoring of bone status in patients with or at-risk of osteoporosis. Summary Imaging provides relevant and valuable information in the assessment of MSK involvement in SLE.

scholarly journals Prognostic Assessment in High-Grade Soft-Tissue Sarcoma Patients: A Comparison of Semantic Image Analysis and Radiomics

Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1929
Author(s):  
Jan C. Peeken ◽  
Jan Neumann ◽  
Rebecca Asadpour ◽  
Yannik Leonhardt ◽  
Joao R. Moreira ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcomas ◽  
Treatment Decision ◽  
Staging System ◽  
Predictive Performance ◽  
Machine Learning Techniques ◽  
Clinical Staging ◽  
Imaging Features ◽  
Prognostic Assessment ◽  
Selection Operator

Background: In patients with soft-tissue sarcomas of the extremities, the treatment decision is currently regularly based on tumor grading and size. The imaging-based analysis may pose an alternative way to stratify patients’ risk. In this work, we compared the value of MRI-based radiomics with expert-derived semantic imaging features for the prediction of overall survival (OS). Methods: Fat-saturated T2-weighted sequences (T2FS) and contrast-enhanced T1-weighted fat-saturated (T1FSGd) sequences were collected from two independent retrospective cohorts (training: 108 patients; testing: 71 patients). After preprocessing, 105 radiomic features were extracted. Semantic imaging features were determined by three independent radiologists. Three machine learning techniques (elastic net regression (ENR), least absolute shrinkage and selection operator, and random survival forest) were compared to predict OS. Results: ENR models achieved the best predictive performance. Histologies and clinical staging differed significantly between both cohorts. The semantic prognostic model achieved a predictive performance with a C-index of 0.58 within the test set. This was worse compared to a clinical staging system (C-index: 0.61) and the radiomic models (C-indices: T1FSGd: 0.64, T2FS: 0.63). Both radiomic models achieved significant patient stratification. Conclusions: T2FS and T1FSGd-based radiomic models outperformed semantic imaging features for prognostic assessment.

SOFT-TISSUE TUMOURS

BMJ ◽  
1959 ◽  
Vol 2 (5149) ◽  
pp. 413-413
Author(s):  
B. S. Cardell
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumours

scholarly journals The Width of the Surgical Margin Does Not Influence Outcomes in Extremity and Truncal Soft Tissue Sarcoma Treated With Radiotherapy

2016 ◽  
Vol 21 (10) ◽  
pp. 1269-1276 ◽  
Author(s):  
Rima Ahmad ◽  
Alex Jacobson ◽  
Francis Hornicek ◽  
Alex B. Haynes ◽  
Edwin Choy ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Surgical Margin
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