Inflammatory Myofibroblastic Tumour in Antimesenteric Border of Descending Colon of Children: A Case Report

2015 ◽  
Vol 3 (1) ◽  
pp. 47-50
Author(s):  
Shahnoor Islam ◽  
AKM Amirul Morshed ◽  
Afiqul Islam
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Inflammatory Myofibroblastic Tumour ◽  
Pathological Findings ◽  
Soft Tissue Lesion ◽  
Soft Tissue Tumours ◽  
Inflammatory Pseudotumour ◽  
Erythrocyte Sedimentation ◽  
Antimesenteric Border

Inflammatory myofibroblastic tumour (IMT) occurring at intraabdominal sites in children has rarely been described. Inflammatory pseudotumour is a soft tissue lesion that may be confused with a sarcoma. It is abbreviated as IMT. Inflammatory myofibroblastic tumour, also known as soft tissue tumours, atypical fibromyxoid tumours, pseudosarcomatous fibromyxoid tumour, plasma cell granuloma, pseudosarcomatous myofibrotic proliferation, post-operative spindle cell nodules. In this paper, we describe a case of inflammatory myofibroblastic tumour (IMT) with an unusual constellation of clinical, pathological findings. A 10-year-old girl had an 7-cm intraabdominal mass accompanied by severe anemia, fever, constipation, weight loss, thrombocytosis, elevated erythrocyte sedimentation rate. Laparotomy was performed. The final pathologic diagnosis was IMT. At the most recent follow up (12months) after excision of the tumour, the patient was symptom-free and there was no evidence of tumour recurrence.J. Paediatr. Surg. Bangladesh 3(1): 47-50, 2012 (January)

scholarly journals Mediastinal Synovial Sarcoma: A Case Report and Literature Review

2003 ◽  
Vol 10 (7) ◽  
pp. 393-395 ◽  
Author(s):  
Linda SL Cheng ◽  
Gary MK Tse ◽  
Wilson WL Li ◽  
TW Lee ◽  
Anthony PC Yim
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Literature Review ◽  
Synovial Sarcoma ◽  
Spindle Cell ◽  
Diagnosis And Treatment ◽  
Soft Tissue Tumours ◽  
Unusual Location ◽  
Synovial Sarcomas ◽  
Proper Diagnosis

Synovial sarcomas are uncommon soft tissue tumours. Immunohistochemistry and cytogenetic techniques are essential for proper diagnosis and differentiation from other spindle cell neoplasms. A case of mediastinal synovial sarcoma is described, of which the unusual location, diagnosis and treatment form the basis of this report.

scholarly journals Surgical Management of Malignant Soft Tissue Tumours in Patients Aged 65 Years or Older

2003 ◽  
Vol 11 (1) ◽  
pp. 28-33 ◽  
Author(s):  
S Osaka ◽  
H Sugita ◽  
E Osaka ◽  
Y Yoshida ◽  
J Ryu
Keyword(s):  
Soft Tissue ◽  
Primary Site ◽  
Surgical Margins ◽  
High Grade ◽  
Soft Tissue Tumours ◽  
Aged Patients ◽  
Surgical Methods ◽  
Cut Surface ◽  
Malignant Soft Tissue

Objective. With the aim to determine the most effective treatment for primary malignant musculoskeletal tumours in patients aged 65 years or older, we reviewed cases of low- and high-grade neoplasms, surgical margins, surgical methods, and the prognoses of elderly and aged patients at our institution. Methods. Records of 25 patients aged 65 years or older who had malignant soft tissue tumours from December 1986 to February 1997 were reviewed. Low- and high-grade neoplasms accounted for 8 and 17 patients, respectively. 11 patients were aged 65 to 69 years, while 14 were 70 years or older. Surgical margins were wide in 19 cases, marginal in 4, and intralesional in 2. Reconstruction was done using 6 musculocutaneous flaps and/or 4 vessel grafts. As adjuvant therapy, radiotherapy was used in 5 cases and chemotherapy in 3. There was no recurrence in patients with wide surgical margins (determined on the basis of gross inspection of the excised tumour and the cut surface); but there was recurrence in 4 patients with marginal margins, and one patient with intralesional margin. Two patients with intralesional, 4 with marginal, and 2 with wide margins, died from recurrence at the primary site and metastasis, or from metastasis without recurrence at the primary site. Results. Follow-up periods ranged from 4 months to 180 months (mean, 91.6 months). The overall 5-year survival rate was 79.6%; for low- and high-grade neoplasms, the figures were 100% and 69.7%, respectively; for those aged 65 to 69 years and in their 70's or older, the figures were 90.9% and 70.1%, respectively. Conclusion. For geriatric patients, wide surgical margins are required to manage both low- and high-grade neoplasms, in order to avoid multiple surgeries.

scholarly journals Conjunctival leiomyosarcoma: A fairly common tumour in an uncommon site

2017 ◽  
Vol 5 ◽  
pp. 2050313X1772406
Author(s):  
Reubina Wadee
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Clinical Medicine ◽  
Spindle Cell Carcinoma ◽  
The Body ◽  
Hiv Positive ◽  
Malignant Tumours ◽  
Spindle Cell Neoplasm ◽  
Soft Tissue Masses

Background: Leiomyosarcomas of soft tissue are malignant tumours that are not infrequently encountered in clinical medicine and histopathology. Such sarcomas of the eye are, however, a rare occurrence. Purpose: Herein, the histopathological features of a case of conjunctival leiomyosarcoma are described. A 38-year-old HIV-positive male, who was otherwise fit and healthy, presented with redness of his right eye and a mass of the conjunctiva. Clinically, he did not have any soft-tissue masses elsewhere in the body. Method: He underwent monoblock excision of the conjunctival mass which was confirmed histologically to be a leiomyosarcoma. Unfortunately, the patient had not returned for follow-up examination. Conclusion: The differential diagnosis of a conjunctival spindle cell neoplasm is broad. While a spindle cell carcinoma is the most likely tumour, other tumours must be borne in mind so as not to misdiagnose primary sarcomas in this unusual location.

scholarly journals Tumour in a tumour: a well-differentiated spindle cell sarcoma within a forearm lipoma

2019 ◽  
Vol 12 (1) ◽  
pp. bcr-2018-227533 ◽  
Author(s):  
James C. R. Wadkin ◽  
Sebastian Senes ◽  
Scott Evans ◽  
Jonathan Stevenson
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Rare Event ◽  
Spindle Cell Sarcoma ◽  
Soft Tissue Tumours ◽  
Cell Sarcoma ◽  
Sarcomatous Change ◽  
Giant Lipoma ◽  
Soft Tissue Masses ◽  
Well Differentiated

Lipomas are common, benign, soft tissue masses in adults. Sarcomatous change within a giant lipoma is a very rare event. We present a case of a woman presenting with a forearm lipoma that subsequently developed a central, well-differentiated, spindle-cell sarcoma within the lipoma. This case underlines the importance of identifying red flags for referral of soft tissue tumours.

scholarly journals Primary renal synovial sarcoma

2012 ◽  
Vol 2 (2) ◽  
pp. 44 ◽  
Author(s):  
Girish D. Bakhshi ◽  
Arshad S. Khan ◽  
Aftab S. Shaikh ◽  
Mohammad Ashraf A. Khan ◽  
Mohammad Adil A. Khan ◽  
...  
Keyword(s):  
Synovial Sarcoma ◽  
Poor Prognosis ◽  
Spindle Cell ◽  
Review Of Literature ◽  
Soft Tissue Tumours ◽  
Renal Tumours ◽  
Spindle Cell Tumours ◽  
Synovial Sarcomas ◽  
Sarcoma Patient

Primary Renal Sarcoma is rare tumor comprising only 1% of all renal tumours. Synovial sarcomas are generally deep-seated tumors arising in the proximity of large joints of adolescents and young adults and account for 5-10% of all soft tissue tumours. Primary synovial sarcoma of kidney is rare and has poor prognosis. It can only be diagnosed by immunohistochemistry. It should be considered as a differential in sarcomatoid and spindle cell tumours. We present a case of 33-year-old female, who underwent left sided radical nephrectomy for renal tumour. Histopathology and genetic analysis diagnosed it to be primary renal synovial sarcoma. Patient underwent radiation therapy and 2 years follow up is uneventful. A brief case report with review of literature is presented.

scholarly journals Retroperitoneal Spindle Cell Tumor: A Case Report

2021 ◽  
Vol 8 ◽  
Author(s):  
Hao Hua ◽  
Zhiwei He ◽  
Linhan Lei ◽  
Huahua Xie ◽  
Zilei Deng ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Spindle Cell ◽  
Cell Tumor ◽  
Tumor Surgery ◽  
Spindle Cell Tumor ◽  
Soft Tissue Density ◽  
The Right ◽  
Upper Abdomen

Spindle cell tumor is very rare. Herein, we report a case of retroperitoneal spindle cell tumor in a 52-year-old female. The patient first presented with a complaint of persistent pain in the right upper abdomen. In the follow-up, a CT scan was performed and showed a retroperitoneal soft tissue density mass measuring 11 cm in diameter. Then, a subsequent operation was performed, and we completely removed the tumor and partially invaded lesions. The tumor was histologically diagnosed as a spindle cell tumor. Therefore, it is imperative for us to enhance the understanding of this seldom found tumor. Surgery remains the best option for treatment.

Improving diagnosis of acute appendicitis with atypical findings by Tc-99m HMPAO leukocyte scan

2002 ◽  
Vol 41 (01) ◽  
pp. 37-41 ◽  
Author(s):  
S. Shung-Shung ◽  
S. Yu-Chien ◽  
Y. Mei-Due ◽  
W. Hwei-Chung ◽  
A. Kao
Keyword(s):  
Acute Appendicitis ◽  
False Positive ◽  
False Positive Rate ◽  
Accurate Method ◽  
Clinical Findings ◽  
Pathological Findings ◽  
Lower Quadrant ◽  
Predictive Values ◽  
Positive Rate

Summary Aim: Even with careful observation, the overall false-positive rate of laparotomy remains 10-15% when acute appendicitis was suspected. Therefore, the clinical efficacy of Tc-99m HMPAO labeled leukocyte (TC-WBC) scan for the diagnosis of acute appendicitis in patients presenting with atypical clinical findings is assessed. Patients and Methods: Eighty patients presenting with acute abdominal pain and possible acute appendicitis but atypical findings were included in this study. After intravenous injection of TC-WBC, serial anterior abdominal/pelvic images at 30, 60, 120 and 240 min with 800k counts were obtained with a gamma camera. Any abnormal localization of radioactivity in the right lower quadrant of the abdomen, equal to or greater than bone marrow activity, was considered as a positive scan. Results: 36 out of 49 patients showing positive TC-WBC scans received appendectomy. They all proved to have positive pathological findings. Five positive TC-WBC were not related to acute appendicitis, because of other pathological lesions. Eight patients were not operated and clinical follow-up after one month revealed no acute abdominal condition. Three of 31 patients with negative TC-WBC scans received appendectomy. They also presented positive pathological findings. The remaining 28 patients did not receive operations and revealed no evidence of appendicitis after at least one month of follow-up. The overall sensitivity, specificity, accuracy, positive and negative predictive values for TC-WBC scan to diagnose acute appendicitis were 92, 78, 86, 82, and 90%, respectively. Conclusion: TC-WBC scan provides a rapid and highly accurate method for the diagnosis of acute appendicitis in patients with equivocal clinical examination. It proved useful in reducing the false-positive rate of laparotomy and shortens the time necessary for clinical observation.

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