Neuropathic bladder

2013 ◽  
pp. 603-638
Author(s):  
John Reynard ◽  
Simon Brewster ◽  
Suzanne Biers
Keyword(s):  
Urinary Tract ◽  
Neurological Disease ◽  
Lower Urinary Tract ◽  
Neuropathic Bladder ◽  
Bladder Management ◽  
Clinical Consequences ◽  
Urine Storage ◽  
Management Techniques ◽  
Lower Urinary

Innervation of the lower urinary tract (LUT) 604 The physiology of urine storage and micturition 608 Bladder and sphincter behaviour in the patient with neurological disease 610 The neuropathic lower urinary tract: clinical consequences of storage and emptying problems 612 Bladder management techniques for the neuropathic patient ...

Management of the neuropathic bladder

2020 ◽  
pp. 651-708
Author(s):  
Suzanne Biers ◽  
Noel Armenakas ◽  
Alastair Lamb ◽  
Stephen Mark ◽  
John Reynard ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Urinary Tract ◽  
Lower Urinary Tract ◽  
Sphincter Function ◽  
Cord Injury ◽  
Bladder Management ◽  
Clinical Consequences ◽  
Management Techniques ◽  
Neurological Conditions ◽  
Tract Infections

A variety of neurological conditions are associated with abnormal bladder and sphincter function, e.g. spinal cord injury (SCI), spina bifida (myelomeningocele), and multiple sclerosis (MS). The bladder and sphincters of such patients are described as ‘neuropathic’. This chapter describes the clinical consequences with the neuropathic lower urinary tract, bladder management techniques, and cystoplasty. It also provides management of incontinence, recurrent urinary tract infections, and hydronephrosis. Finally, it also covers catheters and condoms and artificial urinary sphincters.

scholarly journals Identification of C-Kit-Positive Interstitial Cells in the Dog Lower Urinary Tract and Relationship with Smooth Muscle and Nerves. Hypotheses for a Likely Pacemaker Role.

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Silvana Arrighi ◽  
Giampaolo Bosi ◽  
Debora Groppetti ◽  
Fausto Cremonesi
Keyword(s):  
Smooth Muscle ◽  
Urinary Tract ◽  
Lower Urinary Tract ◽  
Growth Factor Receptor ◽  
Interstitial Cells ◽  
Urine Storage ◽  
Bladder Detrusor ◽  
Cells Of Cajal ◽  
The Relationship ◽  
Lower Urinary

The aim of this work was to give an evidence of the likely presence of interstitial cells in the canine lower urinary tract and to study their possible interactions with the musculature and the intramural innervation. Cryosections of normal canine bladder and urethra were immunofluorescently labelled with c-kit, a transmembrane, tyrosine kinase growth factor receptor, known to be expressed on the interstitial cells of Cajal (ICCs) of the gut. The relationship with antiactin positive smooth muscle cells and PGP9.5-positive intramural innervation was also investigated by confocal microscopy. Anti-c-kit labelling demonstrated a network of elongated and branched c-kit positive cells, which were located in interstitial spaces, oriented in parallel to the smooth muscle bundles that form the bladder muscular layer, irrespective of dog sex. Cells with a similar localization were also PAS- and NADPH-diaphorase-positive. A contact between c-kit immunofluorescent cells and intramural innervation was demonstrated, too. The roles of interstitial cells might include regulation of smooth muscle activity of the bladder detrusor, integrating neuronal signals during urine storage and voiding.

Non-traumatic neurourology

2017 ◽  
Author(s):  
Jalesh N. Panicker ◽  
Clare J. Fowler
Keyword(s):  
Urinary Tract ◽  
Neurological Disease ◽  
Lower Urinary Tract ◽  
Bladder Dysfunction ◽  
Lower Urinary Tract Dysfunction ◽  
Bladder Control ◽  
Patient Health ◽  
Neurological Conditions ◽  
Lower Urinary

This chapter reviews bladder disturbances in non-traumatic neurological conditions and provides an approach to its evaluation and management. The pattern of bladder dysfunction depends upon the level of neurological localisation and accordingly, lesions can be suprapontine, infrapontine/suprasacral (spinal), or infrasacral. The importance of the frontal lobes for bladder control has been confirmed and vascular disease or tumour can result in incontinence. There is better understanding about the very different urological profile of the two sometimes confused conditions, multiple system atrophy and Parkinson’s disease. Guidelines for the management of lower urinary tract dysfunction in multiple sclerosis are reviewed. Lower urinary tract (LUT) dysfunction is common in neurological disease and its importance to patient health and quality of life is now widely recognized.

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