Case 8.13

Author(s):  
Christine U. Lee ◽  
James F. Glockner

37-year-old pregnant woman with episodes of shortness of breath, headache, visual changes, and palpitations occurring with urination Axial fat-suppressed FSE T2-weighted images (Figure 8.13.1) and coronal fat-suppressed SSFP images (Figure 8.13.2) demonstrate a well-defined mass with high T2-signal intensity adjacent to or originating from the left bladder wall. Note also the vascular flow voids near the inferior medial margin of the mass on the axial images, as well as the gravid uterus, on the coronal images....

Author(s):  
Christine U. Lee ◽  
James F. Glockner

69-year-old woman with vaginal bleeding Axial FSE T2-weighted images (Figure 10.4.1) reveal a large infiltrative mass expanding the walls of the vagina and extending laterally into the left pelvic sidewall. Note that the tumor partially encases the rectum and extends into the posterior bladder wall. The lesion shows high signal intensity on axial DWI (b=800 s/mm...


2021 ◽  
pp. 219256822098228
Author(s):  
Bei Yuan ◽  
Lihua Zhang ◽  
Shaomin Yang ◽  
Hanqiang Ouyang ◽  
Songbo Han ◽  
...  

Study Design: Retrospective study. Objectives: Giant cell tumors (GCTs) of the mobile spine can be locally aggressive. This study described and classified the typical and atypical appearance of aggressive spinal GCTs according to imaging findings to help the imaging diagnosis, especially for patients with rapid neurological deficit that may require emergent surgery without biopsy. Methods: Computed tomography (CT) and magnetic resonance imaging (MRI) scans of patients diagnosed with aggressive spinal GCTs at single center were reviewed. Results: Overall, 101 patients with 100 CT images and 94 MR images were examined. All lesions were osteolytic with cortical destruction; 95 lesions showed epidural extension; 90 were centered in the vertebral body; 82 showed pathological fracture and/or collapse of the vertebral body; 78 had pseudotrabeculation on CT; 80 showed low-to-iso signal intensity or heterogeneous high-signal intensity with cystic areas on the T2-weighted images; 9 showed fluid–fluid level on T2-weighted images; and 61 patients showed marked enhancement on contrast-enhanced CT and/or MRI. Forty-one lesions (40.6%) had at least 1 atypical radiographic feature: 19 involved ≥2 segments; 11 were centered in the posterior neural arch; 10 had a paravertebral mass over 2 segments; 16 showed partial margin sclerosis with partial cortical destruction on CT scans; and 3 showed mineralization within the tumor on CT. Eighty-eight patients underwent CT-guided biopsy with a diagnostic accuracy rate of 94.3%. Conclusions: Spinal GCTs might appear more radiologically atypical, and about 40% of the lesions may have at least 1 atypical feature. CT-guided biopsies are recommended for definitive diagnosis.


2005 ◽  
Vol 49 (2) ◽  
pp. 319-322 ◽  
Author(s):  
Ludimyla H.F. Meister ◽  
Patrícia R. Hauck ◽  
Hans Graf ◽  
Gisah A. Carvalho

A 26-year-old pregnant woman presenting with repeated episodes of vaginal bleeding, weight loss, and shortness of breath was diagnosed with choriocarcinoma with metastases to both lungs. Chorionic gonadotropin levels (hCG) were >2.5 x 10(6)mU/mL. Consistent with hCG-induced subclinical hyperthyroidism, she had a suppressed TSH of 0.037mU/L (0.49 - 4.67), a T4 of 18.1µg/dL (4.9 - 10.7), and T3 of 136ng/dL (45 - 137). Chemotherapy with a combined regimen with etoposide, methotrexate, and dactinomycine was started. The initial course was complicated by urosepsis with respiratory distress requiring endotracheal intubation for 3 days. She then improved rapidly, and her thyroid function tests were within normal limits by day 12. Six months later, after ten cycles of chemotherapy, the patient was in remission without signs of residual tumor or hCG-induced paraneoplastic activity.


Author(s):  
Christine U. Lee ◽  
James F. Glockner

31-year-old man with chronic midline back pain; recent spinal MRI suggested a marrow infiltrative disorder Axial FSE T1-weighted images (Figure 14.3.1) demonstrate diffuse decreased signal intensity within the marrow of the iliac bones, with some regions slightly hypointense to adjacent skeletal muscle. Axial fat-suppressed FSE T2-weighted images (...


Author(s):  
Christine U. Lee ◽  
James F. Glockner

3-year-old girl with a chest wall mass that her mother noticed Axial (Figure 13.6.1) and coronal (Figure 13.6.2) FSE T2-weighted images demonstrate a large heterogeneous mass that has multiple regions of high signal intensity and occupies much of the left hemothorax. Note involvement of the lateral chest wall and a lower rib best seen on the coronal images....


Author(s):  
Christine U. Lee ◽  
James F. Glockner

57-year-old woman with a pelvic mass Axial fat-suppressed FSE T2-weighted images (Figure 11.16.1) demonstrate a large heterogeneous mass in the central and right pelvis with regions of high and intermediate signal intensity. Axial postgadolinium 3D SPGR images (Figure 11.16.2) reveal heterogeneous enhancement of the lesion with anterior and inferior cystic or necrotic regions....


Author(s):  
Christine U. Lee ◽  
James F. Glockner

54-year-old postmenopausal woman with vague pelvic pain Axial T2-weighted images from a DWI acquisition (b=0 s/mm2) (Figure 11.13.1) demonstrate a complex central pelvic mass containing an anterior cystic component, as well as a lobulated posterior solid component with mixed, but predominantly low, signal intensity. Corresponding axial diffusion-weighted images (b=800 s/mm...


Author(s):  
Christine U. Lee ◽  
James F. Glockner

27-year-old woman with left lower quadrant pain and a history of endometriosis Axial FSE T2-weighted images (Figure 11.5.1) demonstrate a large, lobulated left adnexal lesion with regions of high and low signal intensity. Coronal fat-suppressed FSE T2-weighted images (Figure 11.5.2) reveal similar findings. Coronal fat-suppressed FSE T1-weighted images (...


Author(s):  
Christine U. Lee ◽  
James F. Glockner

10-year-old girl with urinary frequency and urgency and dysuria Sagittal (Figure 8.12.1) and axial (Figure 8.12.2) fat-suppressed FSE T2-weighted images demonstrate a heterogeneous mass with cystic components in the posterior bladder. An axial T1-weighted FSE image (Figure 8.12.3) shows uniform moderate signal intensity throughout the bladder mass....


Author(s):  
Christine U. Lee ◽  
James F. Glockner

1-month-old female infant with a renal or adrenal mass Axial fat-suppressed FSE T2-weighted images (Figure 6.11.1) reveal a large mass originating from the right adrenal gland with heterogeneously increased signal intensity. Extensive small hyperintense metastases essentially replace the visualized hepatic parenchyma. Axial fat-suppressed FSE images from the 6-week follow-up examination (...


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