scholarly journals COVID-19 in patients with Behçet’s disease: Outcomes and rate of Behçet’s exacerbations in a retrospective cohort

2021 ◽  
Author(s):  
Bünyamin Polat ◽  
Abdulsamet Erden ◽  
Serdar Can Güven ◽  
Berkan Armağan ◽  
Özlem Karakaş ◽  
...  
Keyword(s):  
Behçet’S Disease ◽  
Medical Records ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Behcet's Disease ◽  
Disease Outcomes ◽  
Number Of Patients ◽  
Increasing Trend ◽  
Activity Form ◽  
Pcr Test

ABSTRACT Objectives The aim of this study is to investigate the outcomes of coronavirus disease 2019 (COVID-19) in our cohort of Behçet’s disease (BD) patients and to reveal the rate of BD exacerbations due to COVID-19. Methods Patients who have been followed with a diagnosis of BD were retrospectively investigated for a positive severe acute respiratory syndrome–coronavirus 2 polymerized chain reaction (PCR) test. Data regarding demographics, clinical features and COVID-19 outcomes were collected from medical records for patients with a positive PCR. PCR-positive patients were reached via phone numbers, and ‘Behçet’s Disease Current Activity Form’ (BDCAF) scores for pre- and post-COVID-19 BD symptoms were calculated. Results Out of a total 648 BD patients, 59 were detected to have a positive PCR test. Three of the 59 patients (5.0%) were found to be hospitalized, none of them was admitted to the ICU or died. An increasing trend in the frequency of comorbid diseases and older age was observed in hospitalized patients. 32.2% of BD patients suffered from exacerbation of at least one symptom related to BD. Conclusions We observed no ICU admission or mortality with COVID-19 in our BD patient cohort. A substantial number of patients suffered from exacerbation of BD symptoms.

scholarly journals MicroRNA155 Expression in Relation to BDCAF Scored Behçet's Disease in an Egyptian Patients' Sample

2018 ◽  
Vol 12 (1) ◽  
pp. 115-122 ◽  
Author(s):  
Sally S. Hassouna ◽  
Manal Y. Tayel ◽  
Dalal M. ElKaffash ◽  
Ahmed M. Abdelhady ◽  
Eman H. Elsayed
Keyword(s):  
Behçet’S Disease ◽  
Healthy Subjects ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
White Blood Cells ◽  
Behcet's Disease ◽  
Egyptian Patients ◽  
Activity Form ◽  
Assessment Of Disease Activity

Objective:To discover the possibility of using microRNA155 (miRNA155) expression level as a biomarker of Behçet's Disease (BD) activity or remission.Methods:Thirty BD patients’ white blood cells (WBCs) miRNA155 expression was measured and compared to WBCs miRNA155 expression in 15 healthy subjects. Assessment of disease activity was done using Behçet's Disease Current Activity Form (BDCAF).Results:miRNA155 expression significantly decreases with the increase of BD activity scored by BDCAF.Conclusion:Increased miRNA155 may be used as a biomarker of BD remission and thus in the disease follow up. There could be a prospect of treating the diseaseviamicroRNA 155 effect enhancement.

Cardiovascular Manifestations of Behçet Disease among Egyptian Patients

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Dalia F Mohammed ◽  
Nashwa A El-morshedy ◽  
Mohamed A Teama ◽  
Bassant M Ibrahim
Keyword(s):  
Disease Activity ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Vascular Lesions ◽  
Behçet Disease ◽  
Behcet Disease ◽  
Behcet's Disease ◽  
Current Activity ◽  
Activity Form

Abstract Background Behcet’s disease is an auto immune disease with multisystem affection, the most common manifestations are in the form of oral or genital ulcers, eye affection, recurrent thrombosis . Behcet’s disease is a chronic disease with many sequelae, sometimes fatal, the treatment is by immunosuppressive therapy which also had its implications on the long term, unfortunately it has no sure diagnostic tests and relies mainly on clinical criteria, there are few scores to assess behcet’s disease activity (Behcet's Disease Current Activity Form) BDCAF score is a reliable follow up tool with wide accreditation. BD can virtually involve any organ system, cardiac involvement is variable and sought to occur in the range of 7-46% of patients and may cause myocardial infarction, pericarditis, valve problems, aneurysms or congestive heart failure. Different types of vessels, predominantly veins, can be affected in BD. The frequency of vascular lesions in BD, such as superficial and deep venous thromboses, arterial aneurysms and occlusions, ranges between 7-29%. Aims To assess cardiovascular manifestations for patient diagnosed as Behçet disease (BD) and its correlation to disease activity. Methods This was a cross sectional study which was done on 40 Behcet’s disease patients within the year 2019, it was done for the assessment of cardiovascular manifestations for patient diagnosed as Behçet disease (BD) and its correlation with BDCAF score (Behcet’s disease current activity form). The study group was subjected to full history, clinical examination including activity which was assessed according to BDCAF score (BEHCET'S DISEASE CURRENT ACTIVITY FORM), Assessment of any activity regarding the eyes using fundus examination, routine laboratory investigations including Complete blood count (CBC), Erythrocyte sedimentation rate (ESR), Creactive protein (CRP), lipid profile, liver enzymes. Results it was found that there is a positive correlation between BDCAF (behcet's disease current activity form) and cardiovascular affection (especially valvular lesions and vascular venous affection).

Behçet's Disease Current Activity Form as a Patient's Derived Measure

2016 ◽  
Vol 23 (1) ◽  
pp. 19
Author(s):  
Hyo Jin Choi ◽  
Mi Ryoung Seo ◽  
Hee Jung Ryu ◽  
Han Joo Baek
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Behcet's Disease ◽  
Current Activity ◽  
Activity Form

Cross-cultural adaptation of the Behçet’s Disease Current Activity Form (BDCAF) to Brazilian Portuguese language

2006 ◽  
Vol 26 (8) ◽  
pp. 1263-1267 ◽  
Author(s):  
F. S. Neves ◽  
J. C. B. Moraes ◽  
S. C. Kowalski ◽  
C. Goldenstein-Schainberg ◽  
L. V. Lage ◽  
...  
Keyword(s):  
Behçet’S Disease ◽  
Cultural Adaptation ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Brazilian Portuguese ◽  
Cross Cultural ◽  
Cross Cultural Adaptation ◽  
Behcet's Disease ◽  
Current Activity ◽  
Activity Form
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