scholarly journals Molecular Cloning and Functional Analysis of a Human cDNA Encoding an Escherichia Coli AlkB Homolog, a Protein Involved in DNA Alkylation Damage Repair

1996 ◽  
Vol 24 (5) ◽  
pp. 931-937 ◽  
Author(s):  
Y.-F. Wei ◽  
K. C. Carter ◽  
R.-P. Wang ◽  
B. K. Shell
Keyword(s):  
Escherichia Coli ◽  
Functional Analysis ◽  
Molecular Cloning ◽  
Dna Alkylation ◽  
Alkylation Damage ◽  
Human Cdna ◽  
Damage Repair

scholarly journals Regulation of DNA Alkylation Damage Repair: Lessons and Therapeutic Opportunities

2017 ◽  
Vol 42 (3) ◽  
pp. 206-218 ◽  
Author(s):  
Jennifer M. Soll ◽  
Robert W. Sobol ◽  
Nima Mosammaparast
Keyword(s):  
Dna Alkylation ◽  
Alkylation Damage ◽  
Damage Repair

scholarly journals Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein

2015 ◽  
Vol 43 (18) ◽  
pp. 8801-8816 ◽  
Author(s):  
Giuseppe Perugino ◽  
Riccardo Miggiano ◽  
Mario Serpe ◽  
Antonella Vettone ◽  
Anna Valenti ◽  
...  
Keyword(s):  
Structure Function ◽  
Dna Alkylation ◽  
Alkylation Damage ◽  
Damage Repair ◽  
Thermostable Protein

scholarly journals DNA Alkylation Damage as a Sensor of Nitrosative Stress in Mycobacterium tuberculosis

2003 ◽  
Vol 71 (2) ◽  
pp. 997-1000 ◽  
Author(s):  
Steven I. Durbach ◽  
Burkhard Springer ◽  
Edith E. Machowski ◽  
Robert J. North ◽  
K. G. Papavinasasundaram ◽  
...  
Keyword(s):  
Dna Damage ◽  
Mycobacterium Tuberculosis ◽  
Nitrosative Stress ◽  
Dna Alkylation ◽  
Genotoxic Effects ◽  
Alkylation Damage ◽  
Damage Repair

ABSTRACT One of the cellular consequences of nitrosative stress is alkylation damage to DNA. To assess whether nitrosative stress is registered on the genome of Mycobacterium tuberculosis, mutants lacking an alkylation damage repair and reversal operon were constructed. Although hypersensitive to the genotoxic effects of N-methyl-N′-nitro-N-nitrosoguanidine in vitro, the mutants displayed no phenotype in vivo, suggesting that permeation of nitrosative stress to the level of cytotoxic DNA damage is restricted.

scholarly journals Relevance of DNA Alkylation Damage Repair Systems in Salmonella enterica Virulence

2010 ◽  
Vol 192 (7) ◽  
pp. 2006-2008 ◽  
Author(s):  
Gerard Àlvarez ◽  
Susana Campoy ◽  
Denis A. Spricigo ◽  
Laura Teixidó ◽  
Pilar Cortés ◽  
...  
Keyword(s):  
Salmonella Enterica ◽  
Dna Alkylation ◽  
Alkylation Damage ◽  
Damage Repair ◽  
Repair Systems

ABSTRACT Systematic inactivation of pathways involved in DNA alkylation damage repair demonstrated that inactivation of the ada, ogt, tag, uvrA, and mfd genes is required to detect a Salmonella enterica virulence decrease. Furthermore, the fitness of S. enterica, defective in these genes, is lowered only when the bacterium is orally, but not intraperitoneally, inoculated.

Molecular cloning and functional analysis of GbRVd, a gene in Gossypium barbadense that plays an important role in conferring resistance to Verticillium wilt

Gene ◽  
2016 ◽  
Vol 575 (2) ◽  
pp. 687-694 ◽  
Author(s):  
Jun Yang ◽  
Qing Ma ◽  
Yan Zhang ◽  
Xingfen Wang ◽  
Guiyin Zhang ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Molecular Cloning ◽  
Verticillium Wilt ◽  
Gossypium Barbadense
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