scholarly journals Rapid synthesis of oligodeoxyribonucleotides III. Effect of added carboxylate ion on the efficiency of internucleotide bond formation. Solid-phase synthesis of the dodecanucleotide, d(pT-A-A-C-T-G-C-T-C-A-C-T)

1979 ◽  
Vol 6 (4) ◽  
pp. 1259-1268 ◽  
Author(s):  
M.J. Gait ◽  
R.C. Sheppard
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Bond Formation ◽  
Rapid Synthesis ◽  
Phase Synthesis

scholarly journals Rapid synthesis of oligodeoxyribonucleotides IV. Improved solid phase synthesis of oligodeoxy-ribonucleotides through phosphotriester intermediates

1980 ◽  
Vol 8 (5) ◽  
pp. 1081-1096 ◽  
Author(s):  
M.J. Gait ◽  
M. Singh ◽  
R.C. Sheppard ◽  
M.D. Edge ◽  
A.R. Greene ◽  
...  
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Rapid Synthesis ◽  
Phase Synthesis

scholarly journals Rapid synthesis of internal peptidyl α-ketoamides by on resin oxidation for the construction of rhomboid protease inhibitors

RSC Advances ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 4196-4199
Author(s):  
Tim Van Kersavond ◽  
Raphael Konopatzki ◽  
Merel A. T. van der Plassche ◽  
Jian Yang ◽  
Steven H. L. Verhelst
Keyword(s):  
Protease Inhibitors ◽  
Serine Proteases ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Biological Processes ◽  
Protease Inhibition ◽  
Rapid Synthesis ◽  
Phase Synthesis ◽  
Rhomboid Protease

Rhomboid intramembrane serine proteases are involved in various biological processes. A solid phase synthesis of internal α-ketoamides reported here shows that primed site elements are crucial for rhomboid protease inhibition.

scholarly journals Preparation of canine relaxin by Fmoc-solid phase synthesis and regioselective disulfide bond formation within the A- and B-chains

2013 ◽  
Vol 1 (1) ◽  
pp. 4 ◽  
Author(s):  
Feng Lin ◽  
Julien Tailhades ◽  
Linda J Chan ◽  
Ross A.D Bathgate ◽  
Mohammed Akhter Hossain ◽  
...  
Keyword(s):  
Disulfide Bond ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Bond Formation ◽  
Disulfide Bond Formation ◽  
Phase Synthesis ◽  
Fmoc Solid Phase Synthesis
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