scholarly journals Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors

2011 ◽  
Vol 39 (21) ◽  
pp. e143-e143 ◽  
Author(s):  
Ashok D. Bandaranayake ◽  
Colin Correnti ◽  
Byoung Y. Ryu ◽  
Michelle Brault ◽  
Roland K. Strong ◽  
...  
Keyword(s):  
Cell Lines ◽  
Recombinant Proteins ◽  
Human Cell ◽  
Lentiviral Vectors ◽  
Human Cell Lines ◽  
Rapid Production

Human cell lines for the production of recombinant proteins: on the horizon

2015 ◽  
Vol 32 (6) ◽  
pp. 673-679 ◽  
Author(s):  
Lukas Fliedl ◽  
Johannes Grillari ◽  
Regina Grillari-Voglauer
Keyword(s):  
Cell Lines ◽  
Recombinant Proteins ◽  
Human Cell ◽  
Human Cell Lines

scholarly journals HEK293 Cell Line as a Platform to Produce Recombinant Proteins and Viral Vectors

2021 ◽  
Vol 9 ◽  
Author(s):  
Evan Tan ◽  
Cara Sze Hui Chin ◽  
Zhi Feng Sherman Lim ◽  
Say Kong Ng
Keyword(s):  
Host Cell ◽  
Cell Lines ◽  
Recombinant Proteins ◽  
Human Cell ◽  
Viral Vectors ◽  
Animal Cell ◽  
Hek293 Cells ◽  
Human Cell Lines ◽  
Post Translational Modifications ◽  
Serum Free Suspension

Animal cell-based expression platforms enable the production of complex biomolecules such as recombinant proteins and viral vectors. Although most biotherapeutics are produced in animal cell lines, production in human cell lines is expanding. One important advantage of using human cell lines is the increased potential that the resulting biotherapeutics would carry more “human-like” post-translational modifications. Among the human cell lines, HEK293 is widely utilized due to its high transfectivity, rapid growth rate, and ability to grow in a serum-free, suspension culture. In this review, we discuss the use of HEK293 cells and its subtypes in the production of biotherapeutics. We also compare their usage against other commonly used host cell lines in each category of biotherapeutics and summarise the factors influencing the choice of host cell lines used.

Investigations of the influence of microgravity on the state of human cell lines

2004 ◽  
Vol 10 (5-6) ◽  
pp. 226-228
Author(s):  
L.M. Nosach ◽  
◽  
O.Yu. Povnitsa ◽  
V.L. Zhovnovata ◽  
◽  
...  
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
The State ◽  
Human Cell Lines

scholarly journals Dicalcin suppresses in vitro trophoblast attachment in human cell lines

2021 ◽  
Vol 570 ◽  
pp. 206-213
Author(s):  
Ryohei Saito ◽  
Hiromasa Satoh ◽  
Kayo Aoba ◽  
Hajime Hirasawa ◽  
Naofumi Miwa
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
Human Cell Lines

scholarly journals Differential Effects of Cyanidin and Cyanidin-3-glucoside on Human Cell Lines

2011 ◽  
Vol 17 (6) ◽  
pp. 515-521 ◽  
Author(s):  
Masayuki TAKEUCHI ◽  
Katsuki OHTANI ◽  
Yanju MA ◽  
Sanae KATO ◽  
Shingo SEMBA ◽  
...  
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
Human Cell Lines ◽  
Differential Effects
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