Self-duplexing CUG repeats selectively inhibit mutant huntingtin expression

Nucleic Acids Research ◽

10.1093/nar/gkt825 ◽

2013 ◽

Vol 41 (22) ◽

pp. 10426-10437 ◽

Author(s):

Agnieszka Fiszer ◽

Marta Olejniczak ◽

Paulina Galka-Marciniak ◽

Agnieszka Mykowska ◽

Wlodzimierz J. Krzyzosiak

Keyword(s):

Mutant Huntingtin ◽

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Rhes, a Striatal Specific Protein, Mediates Mutant-Huntingtin Cytotoxicity

Yearbook of Neurology and Neurosurgery ◽

10.1016/s0513-5117(09)79134-3 ◽

2009 ◽

Vol 2009 ◽

pp. 149

Author(s):

J.P. Blass

Keyword(s):

Specific Protein ◽

Mutant Huntingtin

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Mutant Huntingtin Protein Measurement

10.32388/copmta ◽

2020 ◽

Author(s):

Keyword(s):

Mutant Huntingtin ◽

Huntingtin Protein ◽

Mutant Huntingtin Protein ◽

Protein Measurement

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Faculty Opinions recommendation of Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1021808.247719 ◽

2004 ◽

Author(s):

Davis Ng

Keyword(s):

Inclusion Body ◽

Neuronal Death ◽

Mutant Huntingtin ◽

Body Formation ◽

Inclusion Body Formation

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Faculty Opinions recommendation of Mutant huntingtin expression induces mitochondrial calcium handling defects in clonal striatal cells: functional consequences.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1047146.497062 ◽

2006 ◽

Author(s):

Stefano Di Donato

Keyword(s):

Calcium Handling ◽

Mitochondrial Calcium ◽

Mutant Huntingtin ◽

Functional Consequences

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Faculty Opinions recommendation of Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1260969.1381055 ◽

2010 ◽

Author(s):

Hilmar Bading ◽

Ana Oliveira

Keyword(s):

Nmda Receptor ◽

Receptor Activity ◽

Mutant Huntingtin

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Faculty Opinions recommendation of Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14544.472049 ◽

2006 ◽

Author(s):

Stefano Di Donato

Keyword(s):

Neuronal Dysfunction ◽

Mutant Huntingtin ◽

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Faculty Opinions recommendation of Tracking mutant huntingtin aggregation kinetics in cells reveals three major populations that include an invariant oligomer pool.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3660969.3383071 ◽

2010 ◽

Author(s):

Stefano Di Donato

Keyword(s):

Aggregation Kinetics ◽

Mutant Huntingtin ◽

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Faculty Opinions recommendation of Inhibition of lipid signaling enzyme diacylglycerol kinase epsilon attenuates mutant huntingtin toxicity.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.714447811.790002814 ◽

2012 ◽

Author(s):

John Lowe

Keyword(s):

Diacylglycerol Kinase ◽

Lipid Signaling ◽

Mutant Huntingtin

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Faculty Opinions recommendation of TR-FRET-based duplex immunoassay reveals an inverse correlation of soluble and aggregated mutant huntingtin in huntington's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717951315.793456621 ◽

2012 ◽

Author(s):

Roger Barker ◽

Wei-Li Kuan

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Inverse Correlation ◽

Mutant Huntingtin

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Faculty Opinions recommendation of Mutant huntingtin fragmentation in immune cells tracks Huntington's disease progression.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717960625.793464988 ◽

2012 ◽

Author(s):

Stefano Di Donato

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Disease Progression ◽

Immune Cells ◽

Mutant Huntingtin

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