scholarly journals Effect of age and affection status on blood pressure, serum potassium and stature in familial hyperkalaemia and hypertension

2010 ◽  
Vol 26 (5) ◽  
pp. 1547-1553 ◽  
Author(s):  
A. Farfel ◽  
H. Mayan ◽  
S. Melnikov ◽  
E. J. Holtzman ◽  
O. Pinhas-Hamiel ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Serum Potassium ◽  
Affection Status ◽  
Effect Of Age

scholarly journals Blood Pressure and Tooth Loss: A Large Cross-Sectional Study with Age Mediation Analysis

2021 ◽  
Vol 18 (1) ◽  
pp. 285
Author(s):  
José João Mendes ◽  
João Viana ◽  
Filipe Cruz ◽  
Dinis Pereira ◽  
Sílvia Ferreira ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Tooth Loss ◽  
Cross Sectional Study ◽  
Mediation Effect ◽  
Sectional Study ◽  
Cross Sectional ◽  
Undiagnosed Hypertension ◽  
Dental Hospital ◽  
Continuous Measures ◽  
Effect Of Age

We aimed to investigate the association between blood pressure (BP) and tooth loss and the mediation effect of age. A cross-sectional study from a reference dental hospital was conducted from September 2017 to July 2020. Single measures of BP were taken via an automated sphygmomanometer device. Tooth loss was assessed through oral examination and confirmed radiographically. Severe tooth loss was defined as 10 or more teeth lost. Additional study covariates were collected via sociodemographic and medical questionnaires. A total of 10,576 patients were included. Hypertension was more prevalent in severe tooth loss patients than nonsevere tooth lost (56.1% vs. 39.3%, p < 0.001). The frequency of likely undiagnosed hypertension was 43.4%. The adjusted logistic model for sex, smoking habits and body mass index confirmed the association between continuous measures of high BP and continuous measures of tooth loss (odds ratio (OR) = 1.05, 95% CI: 1.03–1.06, p < 0.001). Age mediated 80.0% and 87.5% of the association between periodontitis with both systolic BP (p < 0.001) and diastolic BP (p < 0.001), respectively. Therefore, hypertension and tooth loss are associated, with a consistent mediation effect of age. Frequency of undiagnosed hypertension was elevated. Age, gender, active smoking, and BMI were independently associated with raised BP.

scholarly journals Effect of Age and Body Weight on the Systolic Blood Pressure of the Growing Chicken

1963 ◽  
Vol 42 (6) ◽  
pp. 1465-1466 ◽  
Author(s):  
E.L. Nichols ◽  
D.K. Hotchkiss ◽  
S.L. Balloun
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Systolic Blood Pressure ◽  
Effect Of Age

scholarly journals Effect of age and blood pressure on aortic size and stroke distance.

Heart ◽  
1986 ◽  
Vol 55 (6) ◽  
pp. 560-568 ◽  
Author(s):  
B A Towfiq ◽  
J Weir ◽  
J M Rawles
Keyword(s):  
Blood Pressure ◽  
Effect Of Age ◽  
Stroke Distance ◽  
Aortic Size

scholarly journals Effect of Age and High Blood Pressure on Barorefiex Sensitivity in Man

1971 ◽  
Vol 29 (4) ◽  
pp. 424-431 ◽  
Author(s):  
Brian Gribbin ◽  
Thomas G. Pickering ◽  
Peter Sleight ◽  
Richard Peto
Keyword(s):  
Blood Pressure ◽  
High Blood Pressure ◽  
Effect Of Age

Dose doubling, relative potency, and dose equivalence of potassium-sparing diuretics affecting blood pressure and serum potassium

2016 ◽  
Vol 34 (1) ◽  
pp. 11-19 ◽  
Author(s):  
George C. Roush ◽  
Michael E. Ernst ◽  
John B. Kostis ◽  
Shamima Yeasmin ◽  
Domenic A. Sica
Keyword(s):  
Blood Pressure ◽  
Serum Potassium ◽  
Relative Potency

Serum Potassium Concentration and Use of Ouabain in Experimental Tourniquet Shock

1957 ◽  
Vol 189 (3) ◽  
pp. 605-608 ◽  
Author(s):  
W. F. Rosse ◽  
A. L. Bennett ◽  
A. R. McIntyre
Keyword(s):  
Blood Pressure ◽  
Serum Potassium ◽  
Potassium Level ◽  
Serum Potassium Level ◽  
Potassium Concentration ◽  
Mean Blood Pressure ◽  
Serum Potassium Concentration ◽  
Average Value ◽  
Tourniquet Shock ◽  
The Mean

Shock was induced in dogs by the release of tourniquets which had been applied to the hind legs for 5 hours. The serum potassium level was followed by spaced sampling. It was seen to rise slightly (from an average of 4.02 mEq/l. to an average of 4.66 mEq/l.) during the prerelease period. Five minutes after the release of the tourniquets, the level had risen to an average of 7.50 mEq/l. and thirty minutes after the release, it had risen to an average of 8.56 mEq/l. At the critical point in the progress of the syndrome (when the mean blood pressure was approximately 50 mm Hg) the average value was 8.46 mEq/l. Ouabain was administered and the level of serum potassium was seen to rise, attaining values as high as 14.67 mEq/l. in one case. The results and significance of these increased levels are briefly discussed as well as an animadversion upon the effects of ouabain on the mean blood pressure.

Management of posaconazole-induced pseudohyperaldosteronism

2020 ◽  
Vol 75 (12) ◽  
pp. 3688-3693
Author(s):  
Matthew R Davis ◽  
Minh-Vu H Nguyen ◽  
Thomas J Gintjee ◽  
Alex Odermatt ◽  
Brian Y Young ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Dose Reduction ◽  
Serum Potassium ◽  
Continuous Monitoring ◽  
Therapeutic Interventions ◽  
Serum Concentrations ◽  
Average Decrease ◽  
Before And After ◽  
Repeat Assessment

Abstract Background Posaconazole-induced pseudohyperaldosteronism (PIPH) has been associated with elevated posaconazole serum concentrations. Clinicians are faced with the difficult task of managing patients with PIPH while maintaining the efficacy of antifungal therapy. Commonly, modifications to posaconazole therapy are utilized in managing PIPH, including dosage reduction of posaconazole or switch to an alternative antifungal. Objectives To characterize the management of patients diagnosed with PIPH and their response to various therapeutic interventions. Methods We retrospectively reviewed 20 consecutive adult patients diagnosed with PIPH. Patient data collected included blood pressure, electrolytes, endocrine laboratory values and posaconazole serum concentrations collected before and after therapeutic intervention. Results Of 20 patients included, 17 patients (85%) underwent therapeutic modification, with posaconazole dose reduction (n = 11) as the most common change. Other modifications included discontinuation (n = 3), switch to an alternative antifungal (n = 2) and addition of spironolactone (n = 1). Clinical improvement (decrease in systolic blood pressure and increase in serum potassium) was observed in 9 of 17 patients (52.9%). An average decrease in systolic blood pressure of 7.1 mmHg and increase in serum potassium of 0.22 mmol/L was observed following therapeutic modification. Conclusions We report our experience with PIPH management, for which there is no universally effective strategy. We utilized a stepwise approach for management, starting with posaconazole dose reduction and repeat assessment of clinical and laboratory parameters. If resolution of PIPH is not achieved, an alternative triazole antifungal or the addition of an aldosterone antagonist are additional potential interventions. It is possible for PIPH to persist after therapeutic modification despite these interventions. Thus, early diagnosis and continuous monitoring is warranted.

Acid-Activated Renin Responses to Hydrochlorothiazide, Propranolol and Indomethacin

1978 ◽  
Vol 55 (s4) ◽  
pp. 151s-153s ◽  
Author(s):  
J. K. McKenzie ◽  
E. Reisin
Keyword(s):  
Blood Pressure ◽  
Serum Potassium ◽  
Potassium Concentration ◽  
Hypertensive Patients ◽  
Serum Potassium Concentration ◽  
Active Renin ◽  
Serum Aldosterone ◽  
Low Salt ◽  
Inactive Renin ◽  
Marked Suppression

1. Six essential hypertensive patients (five with low renin) were treated in successive weeks with placebo; hydrochlorothiazide 100 mg (382 μmol)/day; hydrochlorothiazide and 50 mmol of sodium/day diet; hydrochlorothiazide, 50 mmol of sodium diet and propranolol 160 mg (544 μmol)/day; and hydrochlorothiazide, 50 mmol of sodium and indomethacin 100 mg (287 μmol)/day. 2. Although blood pressure remained unchanged and serum potassium fell on diuretic with or without low salt, there was a marked increase of active renin and a lesser increase of inactive renin, resulting in an increased proportion of active to total renin. 3. Propranolol decreased both active and inactive renin, but not significantly. 4. Indomethacin produced a marked suppression of active renin, a smaller reduction in inactive renin, and a reduction of the ratio of active to total renin almost to placebo values. 5. Blood pressure rose to control values on indomethacin despite the fall in renin whereas it fell with propranolol with little change in renin. 6. Serum aldosterone rose with stimulation but remained elevated despite effective renin suppression with indomethacin and continuing reduced serum potassium concentration.

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