scholarly journals PCM-04ESTABLISHMENT OF PAIRED PRIMARY NEUROSPHERE AND MONOLAYER PEDIATRIC BRAIN TUMOR CELL LINES

2016 ◽  
Vol 18 (suppl 3) ◽  
pp. iii139.4-iii140
Author(s):  
Yuchen Du ◽  
Lin Qi ◽  
Mari Kogiso ◽  
Huiyuan Zhang ◽  
Holly Lindsay ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Tumor Cell ◽  
Cell Lines ◽  
Pediatric Brain Tumor ◽  
Tumor Cell Lines ◽  
Brain Tumor Cell ◽  
Pediatric Brain

Pediatric Brain Tumor Cell Lines

2014 ◽  
Vol 116 (2) ◽  
pp. 218-224 ◽  
Author(s):  
Jingying Xu ◽  
Ashley Margol ◽  
Shahab Asgharzadeh ◽  
Anat Erdreich-Epstein
Keyword(s):  
Brain Tumor ◽  
Tumor Cell ◽  
Cell Lines ◽  
Pediatric Brain Tumor ◽  
Tumor Cell Lines ◽  
Brain Tumor Cell ◽  
Pediatric Brain

scholarly journals PDTM-26. TUMOR TREATING FIELDS (TTFIELDS) HAVE ANTI-PROLIFERATIVE EFFECTS ON PEDIATRIC BRAIN TUMOR CELL LINES AT CLINICALLY DELIVERABLE FIELD SETTINGS

2017 ◽  
Vol 19 (suppl_6) ◽  
pp. vi195-vi195
Author(s):  
Joshua Branter ◽  
Maria Estevez-Cebrero ◽  
Richard Grundy ◽  
Surajit Basu ◽  
Stuart Smith
Keyword(s):  
Brain Tumor ◽  
Tumor Cell ◽  
Cell Lines ◽  
Pediatric Brain Tumor ◽  
Tumor Cell Lines ◽  
Tumor Treating Fields ◽  
Brain Tumor Cell ◽  
Pediatric Brain

Pediatric brain tumor cell lines exhibit miRNA-depleted, Y RNA-enriched extracellular vesicles

2022 ◽  
Author(s):  
Setty M. Magaña ◽  
Timothy E. Peterson ◽  
Jared E. Evans ◽  
Paul A. Decker ◽  
Vernadette Simon ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Tumor Cell ◽  
Cell Lines ◽  
Extracellular Vesicles ◽  
Pediatric Brain Tumor ◽  
Tumor Cell Lines ◽  
Brain Tumor Cell ◽  
Pediatric Brain

Synthesis and in vitro cytotoxic activity of novel hexahydro-2H-pyrido[1,2-b]isoquinolines against human brain tumor cell lines

1997 ◽  
Vol 7 (23) ◽  
pp. 2945-2950 ◽  
Author(s):  
Axel Monsees ◽  
Sabine Laschat ◽  
Marc Hotfilder ◽  
Johannes Wolff ◽  
Klaus Bergander ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Tumor Cell ◽  
Human Brain ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Tumor Cell Lines ◽  
Human Brain Tumor ◽  
Brain Tumor Cell

WEE1 gene silencing can reduce Bcl2 expression in brain tumor cell lines

2011 ◽  
Vol 44 (13) ◽  
pp. S205
Author(s):  
Hosseini Ahmad ◽  
Rahnama Susan ◽  
Jaberipour Mansooreh ◽  
Habib-Agahi Mojtaba
Keyword(s):  
Brain Tumor ◽  
Tumor Cell ◽  
Gene Silencing ◽  
Cell Lines ◽  
Tumor Cell Lines ◽  
Brain Tumor Cell ◽  
Bcl2 Expression

scholarly journals Expression of PPARγ and Its Ligand-dependent Growth Inhibition in Human Brain Tumor Cell Lines

2002 ◽  
Vol 93 (6) ◽  
pp. 660-666 ◽  
Author(s):  
Mihoko Kato ◽  
Takashi Nagaya ◽  
Miyuki Fujieda ◽  
Kiyoshi Saito ◽  
Jun Yoshida ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Tumor Cell ◽  
Human Brain ◽  
Growth Inhibition ◽  
Cell Lines ◽  
Tumor Cell Lines ◽  
Human Brain Tumor ◽  
Brain Tumor Cell ◽  
Dependent Growth

scholarly journals Activities of Some Medicinal Plants on the Proliferation and Invasion of Brain Tumor Cell Lines

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Saidu I. Ngulde ◽  
Umar K. Sandabe ◽  
Roger Abounader ◽  
Ying Zhang ◽  
Isa M. Hussaini
Keyword(s):  
Brain Tumor ◽  
Medicinal Plants ◽  
Tumor Cell ◽  
Cell Line ◽  
Cell Lines ◽  
Anticancer Drugs ◽  
Tumor Cell Lines ◽  
U251 Cell ◽  
Brain Tumor Cell ◽  
Securidaca Longepedunculata

Cancer is a debilitating disease that is on the increase in both developed and developing countries. Anticancer drugs are often expensive, have narrow spectrum of activities, and are associated with toxicities and side effects such as myelosuppression, immunosuppression, gastrointestinal disturbance, alopecia, skin toxicity, and hepatotoxicity. Plants have been the major source of anticancer drugs both in orthodox and traditional medicine. Many of the plants claimed by the traditional medicine practitioners (TMPs) to be effective in the treatment of cancer are yet to be evaluated scientifically. In this work, five medicinal plants used by TMPs in Borno State, Nigeria, were tested against two brain tumor cell lines. Ethanol extracts of Securidaca longepedunculata, Andira inermis subsp. rooseveltii, Annona senegalensis, Carissa edulis, and Parinari polyandra were used. U87 and U231 brain tumor cell lines were used for proliferation assay, U251 cell line was used for the invasion assay in collagen V coated inserts, and U87 cell line was used for the western blot detection of cleaved Poly-ADP-Ribose-Polymerase (PARP). The result revealed that all tested extracts significantly (p<0.05) inhibited the proliferation of U87 and U231 cell lines with the respective IC50 values ranging between 8 and 20 μg/ml for S. longepedunculata and 100 and 90 μg/ml for P. polyandra. The five extracts significantly (p<0.05) inhibited the invasion of U251 cell line at the concentration of 10 μg/ml (S. longepedunculata), 20 μg/ml (A. inermis), 50 μg/ml (A. senegalensis), 50 μg/ml (C. edulis), and 50 μg/ml (P. polyandra). Securidaca longepedunculata extract induced the cleavage of PARP. It was concluded that these medicinal plants have antiproliferative and anti-invasive activities and possess good prospects as source of anticancer agents especially S. longepedunculata which induced apoptosis in U87 cell line.

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