Systemic sclerosis in an anaesthetist

2020 ◽  
Vol 70 (6) ◽  
pp. 442-444
Author(s):  
N Magnavita ◽  
R R Di Prinzio ◽  
P M Soave

Abstract Introduction Systemic sclerosis is a potentially devastating disease in which the aetiology and pathogenesis has not yet been fully understood. It has been associated with occupational exposure to silica, vinyl chloride, solvents and other chemical agents. Case summary In this paper, we present the case of an anaesthetist who developed scleroderma after an occupational exposure to volatile anaesthetic gases (halothane, sevoflurane, isoflurane and enflurane) in operating theatres with poor scavenging systems and we discuss the possible causal link between occupational exposure and the disease. Conclusions The case reported is the second that we are aware of in recent years. Reporting scleroderma cases in workers may be the first step in assessing the causal link between occupational exposure to anaesthetic gases and the disease.

Author(s):  
Barry S. Levy

This chapter describes occupational and environmental liver disorders. It describes the types of liver function and types of liver damage, and how these functions and this damage can be assessed. Workers in healthcare and solid waste management are at increased risk hepatitis B virus and hepatitis C virus infections. Occupational exposure to swine is associated with hepatitis E virus infection. More than 100 industrial chemicals can be acutely hepatotoxic in experimental animals or humans. Metabolic reactions may affect the hepatotoxicity of chemicals. Occupational exposure to organic solvents can cause toxic hepatitis. Occupational exposure to vinyl chloride monomer has been causally associated with toxicant-associated fatty liver disease as well as a form of non-cirrhotic portal hypertension. Several agents can cause cancer of the liver or bile ducts. Vinyl chloride monomer is causally associated with angiosacoma of the liver. Arsenic causes liver cancer. Dietary exposure to aflatoxins can cause hepatoceulluar carcinoma.


2000 ◽  
Vol 108 (8) ◽  
pp. 793-795 ◽  
Author(s):  
I Hozo ◽  
D Miric ◽  
L Bojic ◽  
L Giunio ◽  
I Lusic ◽  
...  

1975 ◽  
Vol 3 (3) ◽  
pp. 263-266
Author(s):  
David B. Gibb

A scavenging device for the Bennett BA–4 “Anaesthesia Ventilator “is described. Anaesthetic gases are vented outside the operating theatres by means of Venturi-type suction apparatus. The unit is very efficient under normal working conditions and no interference with ventilator function has been observed.


Chemosphere ◽  
2014 ◽  
Vol 104 ◽  
pp. 25-31 ◽  
Author(s):  
M. Jumpponen ◽  
H. Rönkkömäki ◽  
P. Pasanen ◽  
J. Laitinen

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