scholarly journals Nasal Microbiota Changes are Associated with Progression to Lower Respiratory Infection Following Respiratory Syncytial Virus Upper Respiratory Infection in Hematopoietic Cell Transplant Recipients

2016 ◽  
Vol 3 (suppl_1) ◽  
Author(s):  
Dimpy Shah ◽  
Nadim J. Ajami ◽  
Shashank S. Ghantoji ◽  
Samuel Shelburne ◽  
Danielle El-Haddad ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Respiratory Infection ◽  
Cell Transplant ◽  
Lower Respiratory Infection ◽  
Transplant Recipients ◽  
Hematopoietic Cell Transplant ◽  
Upper Respiratory Infection ◽  
Upper Respiratory ◽  
Syncytial Virus ◽  
Nasal Microbiota

scholarly journals Is Fever a Red Flag for Bacterial Pneumonia in Children With Viral Bronchiolitis?

2019 ◽  
Vol 6 ◽  
pp. 2333794X1986866 ◽  
Author(s):  
Dominique Elmore ◽  
Balfaqih Yaslam ◽  
Krista Putty ◽  
Thomas Magrane ◽  
Anthony Abadir ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Respiratory Syncytial Virus ◽  
Early Diagnosis ◽  
Respiratory Infection ◽  
Bacterial Pneumonia ◽  
Upper Respiratory Infection ◽  
Red Flag ◽  
Upper Respiratory ◽  
Syncytial Virus ◽  
Secondary Bacterial Pneumonia

We hypothesized that fever in children with viral bronchiolitis indicates the need for consideration of superimposed bacterial pneumonia. We conducted a retrospective study of 349 children aged 2 years and younger with diagnoses of respiratory syncytial virus (RSV) and viral upper respiratory infection. Data were analyzed using Pearson χ2 test. One hundred seventy-eight children had RSV with no other identified virus. The majority of children (56%) who had only RSV were afebrile. Febrile children with RSV were over twice as likely to be diagnosed with bacterial pneumonia as those who were afebrile (60% vs 27%, P < .001). In the 171 children who had bronchiolitis caused by a virus other than RSV, 51% were afebrile. These children were 8 times more likely to be diagnosed with pneumonia than those who were afebrile (65% vs 8%, P < .001). Evaluation of febrile children with viral bronchiolitis may allow early diagnosis and treatment of secondary bacterial pneumonia.

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