scholarly journals Role of multidetector CT Coronary Angiography in Assessment of the prevalence and plaque composition between dyslipidemic and non dyslipidemic patients

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
S A Elsaed ◽  
K E Allam ◽  
E A S Geneidi ◽  
A S Abdelrahman
Keyword(s):  
Coronary Angiography ◽  
Multidetector Ct ◽  
Multislice Ct ◽  
Coronary Plaque ◽  
Distal Segment ◽  
Ct Coronary Angiography ◽  
Plaque Burden ◽  
Plaque Composition ◽  
New Applications

Abstract Purpose To highlight the role of multislice CT coronary angiography with its new applications such as reformatted images, and high resolution imaging, regarding coronary plaque composition and prevalence in dyslipidemic and non dyslipidemic patients Methods The study included 30 patients, 15 non dyslipidemic and 15 dyslipidemic patients. Each patient included in the study was subjected to full history taking, reviewing medical sheet. CTCA was performed for all patients followed by analysis of the plaque composition and percent stenosis using the axial images and multiplanar reconstruction. Results It was found that dyslipidemic patients had more plaque burden than non dyslipidemic. The dyslipidemic patients were more liable for multiple and soft plaques, mainly appreciated at the distal segment of the coronary arteries while non dyslipidemic were more liable for single and calcific/mixed plaques. Thus, may encourage the clinician to use lipid lower drugs as primary or secondary intervention for CAD.

Non invasive cardiac vein mapping: Role of multislice CT coronary angiography

2012 ◽  
Vol 81 (11) ◽  
pp. 3262-3269 ◽  
Author(s):  
Roberto Malagò ◽  
Andrea Pezzato ◽  
Camilla Barbiani ◽  
Giuseppe Sala ◽  
Giulia A. Zamboni ◽  
...  
Keyword(s):  
Coronary Angiography ◽  
Multislice Ct ◽  
Ct Coronary Angiography ◽  
Non Invasive

scholarly journals Multi-slice CT coronary angiography assessment of remodeling index in patients with low- to intermediate-risk stable angina

2019 ◽  
Vol 71 (1) ◽  
Author(s):  
Shaimaa A. Mostafa ◽  
Tarek Aboelazem ◽  
Osama Sanad ◽  
Haytham Abdelghafar ◽  
Ahmed Azam
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Artery ◽  
Coronary Angiography ◽  
Stable Angina ◽  
Positive Family History ◽  
Ct Coronary Angiography ◽  
Plaque Burden ◽  
Intermediate Risk ◽  
Remodeling Index ◽  
The Mean

Abstract Background Early identification of vulnerable plaques by remodeling index prior to rupture and development of acute event is of considerable importance especially by a reliable non-invasive method as CT coronary angiography (CTA), so we aim to evaluate coronary artery remodeling index in patients with low- to intermediate-risk stable angina by CTA. Results This single-center, cross-sectional, observational study included 150 patients with stable angina with normal resting ECG, negative markers, normal systolic function by 2D echocardiography (EF > 50%), and without regional wall motion abnormality at rest who were referred to MSCT evaluation of the coronary artery tree; the mean age was 56.8 ± 6.4 years, 83.3% had one-vessel disease, and 16.7% had two-vessel diseases. The mean remodeling index (RI) was 1.04 ± 0.28, 38% had significant positive remodeling, LAD was the most affected vessel (55.3), and proximal lesions were predominant in 48.5%; there was a statistically significant positive correlation between RI and cholesterol, triglyceride, LDL, duration of DM, HBA1c, and plaque burden (P < 0.001) and a statistically significant negative correlation with HDL (P < 0.001). Predictors of higher RI were positive family history, diabetes mellitus, low HDL, HBA1c, and plaque burden% (P < 0.001). Patients with remodeling index > 1.1 were diabetic, hypertensive, smoker, with longer duration of diabetes mellitus, higher HBA1c, cholesterol, triglyceride, LDL, plaque burden, wall lumen ratio, stenosis area, and lower HDL. Conclusion CTA was able to detect the presence and extent of early, non-obstructive but significant coronary artery-positive remodeling in patients with low- to intermediate-risk stable angina patients. Trial registration NCT03963609, 22 May 2019

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