Evaluation of the efficacy of homologous autoinoculation therapy in treatment of multiple recalcitrant warts

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Nisreen Abbas Abdelmonaem ◽  
Maha Adel shaheen ◽  
Tamer Mohsen Foad ◽  
Rania Mahmoud Elhusseiny

Abstract Background Warts are infections caused by human papillomavirus (HPV). There are new trends towards the use of immunotherapy in treatment of warts. Homologous autoinoculation is a minimally invasive procedure, which treats warts by stimulating a specific immune response against HPV Objective To evaluate the efficacy of autoinoculation therapy in treatment of multiple recalcitrant warts. Methods Under local anesthesia and aseptic condition, inoculum was collected by paring a wart by scalpel and by pressing it between two sterile glass slides. After making a subcutaneous Pocket in non-dominant forearm, the inoculum was introduced in the subcutaneous pocket with forceps and dressed. Follow up for 1,2,12 and 16 weeks was done. Results Fourty patients were included. At 12 weeks of therapy 42.5% showed complete clearance, 27.5% showed moderate clearance, 15% showed mild clearance and 12.5% showed treatment failure. No significant complication was documented after 1 and 2 weeks of follow up except in 3 patients in form of mild inflammation and mild pain. There was no recurrence at16 weeks follow up session. Conclusion Autoinoculation is simple and effective method in treatment of different types of warts including genital wart. It also prevents recurrence.

2005 ◽  
Vol 30 (4) ◽  
pp. 365-368 ◽  
Author(s):  
P. H. J. BULLENS ◽  
M. DRIESPRONG ◽  
H. LACROIX ◽  
J. VEGTER

Thirty-three symptomatic scaphoid non-unions were treated by a simple, minimally invasive procedure using a percutaneous autologous corticocancellous bone graft. After an average follow-up of 3.5 years, union was observed in 29 cases. These patients had no, or mild, pain at work and an almost normal range of motion and grip strength. No progression to osteoarthritis was observed.


Hand Surgery ◽  
1998 ◽  
Vol 03 (02) ◽  
pp. 225-235
Author(s):  
Toshihiko Imaeda ◽  
Ryogo Nakamura ◽  
Kenji Tsunoda ◽  
Kentaro Watanabe

Thirteen of 15 patients with ulnocarpal abutment syndrome who underwent an arthroscopic wafer procedure since 1991 were seen in follow-up at least six months postoperatively. An arthroscopic wafer procedure was performed during which the triangular fibrocartilage complex (TFCC) was partially removed with a blade and a basket punch was made through the 4–5 arthroscopic portal. The ulnar head was then partially removed with a motorized burr through the 4–5 or 6R portal. The modified Mayo wrist score was used to evaluate the results. Four wrists produced excellent results; six wrists, good; two wrists, fair; and one wrist, poor. The wrists with a null or negative ulnar variance after the procedure achieved a better result than those with a remaining positive ulnar variance at the most prominent as well as at the deepest level of the resected ulna. The arthroscopic wafer procedure offers the benefits of a minimally invasive procedure; however, it is technically demanding to remove the ulnar head with a negative ulnar variance at the most prominent level as well as at the deepest level of the resected ulnar head.


2006 ◽  
Vol 58 (suppl_1) ◽  
pp. ONS-59-ONS-68 ◽  
Author(s):  
Gun Choi ◽  
Sang-Ho Lee ◽  
Pradyumna Pai Raiturker ◽  
Seungcheol Lee ◽  
Yu-Sik Chae

Abstract OBJECTIVE: Percutaneous endoscopic transforaminal discectomy is often used as a minimally invasive procedure for lumbar disc herniation. However, a transforaminal approach posts limitations at the L5–S1 level owing to anatomic constraints, such as a high iliac crest or small intervertebral foramen and especially for migrated large intracanalicular disc herniations. We discuss the procedure and clinical results of percutaneous endoscopic interlaminar discectomy using a rigid working channel endoscope at the L5–S1 level and the relevant surgical anatomy. METHODS: We performed percutaneous endoscopic discectomy through the interlaminar approach in 67 patients who satisfied our inclusion criteria during the period from March 2002 to November 2002. All procedures were performed under local anesthesia. Under fluoroscopic guidance, we performed discography using indigocarmine mixed with radio-opaque dye. The 6-mm working channel endoscope was then introduced into the epidural space. Herniated disc material was removed using forceps and laser under clear endoscopic visualization. We retrospectively evaluated the 65 cases with more than 1.5 years of follow-up. The patients were evaluated using the visual analogue scale (VAS) and the Oswestry Disability Index (ODI). RESULTS: VAS for leg pain (preoperative mean, 7.89; postoperative mean, 1.58) and ODI (preoperative mean, 57.43; postoperative mean, 11.52) showed statistically significant (P = 0.00) improvement in their values at the last follow-up examination compared with preoperative scores. Of the study group, 90.8% individuals showed favorable result. The mean hospital stay was 12 hours. The average time to return to work was 6.79 weeks. Complications included two cases of dural injury with cerebrospinal fluid leakage, nine cases of dysesthesia that were transient, and one case of recurrence. Two patients required conversion to open procedure at the initial operation. There was no evidence of infection in any patients. CONCLUSION: Percutaneous endoscopic interlaminar discectomy is a safe, effective, and minimally invasive procedure for the treatment of intracanalicular disc herniations at the L5–S1 level in properly selected cases, especially when the transforaminal approach is not possible because of anatomic constraints.


Author(s):  
C. Deubel ◽  
D. Böhringer ◽  
A. Anton ◽  
T. Reinhard ◽  
J. Lübke

Abstract Background Excimer laser trabeculotomy (ELT) is a minimally invasive procedure to lower the intraocular pressure (IOP) via a photo-ablative laser that is applied to the trabecular meshwork. With this procedure, it is possible to improve the outflow of the aqueous humor. Until now, a limited number of studies examining mostly relatively small sample sizes with midterm follow-up exist. We therefore present the analysis of a large ELT cohort in a long-term follow-up. Methods We recorded data from 580 patients who underwent ELT or combined ELT with cataract surgery at our institution from November 2000 until March 2011. A total of 512 patients with primary open angle glaucoma (POAG), pseudoexfoliation glaucoma (PEX), and ocular hypertension (OHT) were included in the analysis. At every follow-up examination, the usage of IOP-lowering medication and the IOP were recorded. Failure criteria were defined as the need for another surgical glaucoma procedure, when the IOP was not 21 mmHg or less and a reduction of 20% from the baseline was not achieved with (qualified success) or without (absolute success) additional medication. Statistical analysis was done using Kaplan-Meier analysis and Cox regression. Results Four hundred twenty-eight patients underwent combined cataract and ELT surgery, and 84 underwent solitary ELT surgery. After a median follow-up time of 656 days, 87% (combined surgery) and 66% (ELT) of the patients did not have to undergo another IOP-lowering intervention; 47/31% were classified as a qualified success and 31/11% as a complete success. The IOP-lowering medication, however, could not be significantly reduced within that time period. Conclusion Especially when combined with cataract surgery, ELT is a feasible minimally invasive procedure to lower the IOP on a mid- to long-term basis. Over the long term, however, IOP-lowering medication could not be reduced.


2010 ◽  
Vol 9 (6) ◽  
pp. 567
Author(s):  
X. Quni ◽  
I. Haxhiu ◽  
H. Aliu ◽  
N. Baftiu ◽  
M. Toska ◽  
...  

2019 ◽  
Vol 39 (1) ◽  
pp. 70-73 ◽  
Author(s):  
Janavikula Sankaran Rajkumar ◽  
Aluru Jayakrishna Reddy ◽  
Ravikumar Radhakrishnan ◽  
Anirudh Rajkumar ◽  
Syed Akbar ◽  
...  

2015 ◽  
Vol 1 (2) ◽  
Author(s):  
Ghania Masood ◽  
Iffat Rehman ◽  
Saquib Khawar ◽  
Khurram A Mufti ◽  
Imran K. Niazi

Renal angiomyolipomas (AML) are benign lesions usually left alone. However, lesions larger than 4 cm carry the risk of spontaneous haemorrhage and need treatment. Angiography and embolisation are the current standard of care particularly in patients with high operative risks. Angio-embolisation is a safe, minimally invasive procedure preserving maximum renal parenchyma, with the added advantage of preventing peri-procedural morbidity. Two cases of AML are presented in this case series. Key words: Angiomyolipoma, embolisation, renal 


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