scholarly journals Synovial fluid proteomic fingerprint: S100A8, S100A9 and S100A12 proteins discriminate rheumatoid arthritis from other inflammatory joint diseases

Rheumatology ◽  
2010 ◽  
Vol 49 (4) ◽  
pp. 671-682 ◽  
Author(s):  
A. Baillet ◽  
C. Trocme ◽  
S. Berthier ◽  
M. Arlotto ◽  
L. Grange ◽  
...  
Biomedicines ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 902
Author(s):  
Susanne N. Wijesinghe ◽  
Mark A. Lindsay ◽  
Simon W. Jones

Osteoarthritis (OA) and rheumatoid arthritis (RA) are two of the most common chronic inflammatory joint diseases, for which there remains a great clinical need to develop safer and more efficacious pharmacological treatments. The pathology of both OA and RA involves multiple tissues within the joint, including the synovial joint lining and the bone, as well as the articular cartilage in OA. In this review, we discuss the potential for the development of oligonucleotide therapies for these disorders by examining the evidence that oligonucleotides can modulate the key cellular pathways that drive the pathology of the inflammatory diseased joint pathology, as well as evidence in preclinical in vivo models that oligonucleotides can modify disease progression.


1997 ◽  
Vol 40 (3) ◽  
pp. 520-526 ◽  
Author(s):  
Salima Sadallah ◽  
Estelle Lach ◽  
Hans U. Lutz ◽  
Sibylle Schwarz ◽  
Pierre-André Guerne ◽  
...  

2021 ◽  
Vol 2 (1) ◽  
pp. 25-32
Author(s):  
Danilo Jeremić ◽  
Boris Gluščević ◽  
Stanislav Rajković ◽  
Želimir Jovanović ◽  
Branislav Krivokapić

Osteoarthritis, osteoarthrosis, and osteoarthropathy are diseases that doctors encounter daily in their practice. The use of all three terms is customary, often without a clear justification as to why a particular term is used for a particular case. In the past several decades, doctors mainly differentiated among these diseases based on clinical presentation and radiography. In the past several years, however, significant progress has been made in the field of biochemical, immunological, and cytohistological research, which has provided explanations for the pathogenesis of these conditions, enabled defining differences amongst them and facilitated the use of appropriate terms for each one of these diseases. The term arthritis (osteoarthritis) should be used exclusively for primarily inflammatory joint diseases-rheumatoid arthritis, juvenile arthritis, reactive arthritis (Reiter's syndrome). If the etiology is infectious, this must also be emphasized-septic (purulent) arthritis, tuberculous arthritis. Arthrosis (osteoarthrosis) relates to changes in the joints occurring due to pathological processes within the joint itself, but which, in their basis, are not inflammatory. Arthropathy is a term for joint disease stemming from another diseased organ or system of organs.


2013 ◽  
Vol 52 (4) ◽  
pp. 287-294
Author(s):  
Hisashi IWAMOTO ◽  
Iwao EMURA ◽  
Hiroyuki USUDA ◽  
Hidekichi TAKATO ◽  
Mitsuru IKEDU ◽  
...  

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