Physiologically Based Pharmacokinetic Model Use in Risk Assessment—Why Being Published Is Not Enough

Toxicological Sciences ◽

10.1093/toxsci/kfr295 ◽

2011 ◽

Vol 126 (1) ◽

pp. 5-15 ◽

Author(s):

Eva D. McLanahan ◽

Hisham A. El-Masri ◽

Lisa M. Sweeney ◽

Leonid Y. Kopylev ◽

Harvey J. Clewell ◽

...

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Risk Assessment of Perfluorooctane Sulfonate (PFOS) using Dynamic Age Dependent Physiologically based Pharmacokinetic Model (PBPK) across human lifetime

Environmental Research ◽

10.1016/j.envres.2021.111287 ◽

2021 ◽

pp. 111287

Author(s):

Deepika Deepika ◽

Raju Prasad Sharma ◽

Marta Schuhmacher ◽

Vikas Kumar

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Perfluorooctane Sulfonate ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

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Human risk assessment of di-isobutyl phthalate through the application of a developed physiologically based pharmacokinetic model of di-isobutyl phthalate and its major metabolite mono-isobutyl phthalate

Archives of Toxicology ◽

10.1007/s00204-021-03057-5 ◽

2021 ◽

Author(s):

Seung-Hyun Jeong ◽

Ji-Hun Jang ◽

Hea-Young Cho ◽

Yong-Bok Lee

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Major Metabolite ◽

Physiologically Based Pharmacokinetic Model ◽

Human Risk Assessment ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Development of a physiologically-based pharmacokinetic model of 2-phenoxyethanol and its metabolite phenoxyacetic acid in rats and humans to address toxicokinetic uncertainty in risk assessment

Regulatory Toxicology and Pharmacology ◽

10.1016/j.yrtph.2015.07.012 ◽

2015 ◽

Vol 73 (2) ◽

pp. 530-543 ◽

Author(s):

John A. Troutman ◽

David L. Rick ◽

Sharon B. Stuard ◽

Jeffrey Fisher ◽

Michael J. Bartels

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Phenoxyacetic Acid ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Sex-specific risk assessment of PFHxS using a physiologically based pharmacokinetic model

Archives of Toxicology ◽

10.1007/s00204-017-2116-5 ◽

2017 ◽

Vol 92 (3) ◽

pp. 1113-1131 ◽

Author(s):

Sook-Jin Kim ◽

Hwajin Shin ◽

Yong-Bok Lee ◽

Hea-Young Cho

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Specific Risk ◽

Physiologically Based

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Health Risk Assessment for Benzene Occupational Exposure Using Physiologically Based Pharmacokinetic Model and Dose-Response Model

2009 3rd International Conference on Bioinformatics and Biomedical Engineering ◽

10.1109/icbbe.2009.5162898 ◽

2009 ◽

Author(s):

Yang Wang ◽

Mao Liu ◽

Deyin Huang

Keyword(s):

Risk Assessment ◽

Occupational Exposure ◽

Health Risk ◽

Health Risk Assessment ◽

Dose Response ◽

Pharmacokinetic Model ◽

Response Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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ChemInform Abstract: Analytic Solution of a Linear Physiologically Based Pharmacokinetic Model Prototype Useful in Risk Assessment

10.1002/chin.199421323 ◽

2010 ◽

Vol 25 (21) ◽

pp. no-no

Author(s):

R. N. BROWN

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Analytic Solution ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Risk assessment for humans using physiologically based pharmacokinetic model of diethyl phthalate and its major metabolite, monoethyl phthalate

Archives of Toxicology ◽

10.1007/s00204-020-02748-9 ◽

2020 ◽

Vol 94 (7) ◽

pp. 2377-2400 ◽

Author(s):

Seung-Hyun Jeong ◽

Ji-Hun Jang ◽

Hea-Young Cho ◽

Yong-Bok Lee

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Major Metabolite ◽

Diethyl Phthalate ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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P215 - Risk assessment in humans using physiologically based pharmacokinetic model of diisobutyl phthalate and its major metabolite, monoisobutyl phthalate: Development and evaluation of model

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2020.04.216 ◽

2020 ◽

Vol 35 (1) ◽

pp. S87-S88

Author(s):

Yong-Bok Lee ◽

Hea-Young Cho ◽

Seung-Hyun Jeong ◽

Ji-Hun Jang

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Major Metabolite ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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A computer program linking physiologically based pharmacokinetic model with cancer risk assessment for breast-fed infants

Computer Methods and Programs in Biomedicine ◽

10.1016/0169-2607(94)01616-n ◽

1995 ◽

Vol 46 (2) ◽

pp. 155-163 ◽

Author(s):

Janusz Z. Byczkowski ◽

Jeffrey W. Fisher

Keyword(s):

Risk Assessment ◽

Cancer Risk ◽

Computer Program ◽

Pharmacokinetic Model ◽

Cancer Risk Assessment ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

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Development of a Physiologically-Based Pharmacokinetic Model of Trichloroethylene and Its Metabolites for Use in Risk Assessment

10.21236/ada451076 ◽

2004 ◽

Author(s):

Tammie R. Covington ◽

Harvey J. Clewell ◽

Jeffrey W. Fisher

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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