scholarly journals Inhibition of 125I-Human Follicle-Stimulating Hormone Binding to Receptor by a Low Molecular Weight Fraction of Bovine Follicular Fluid: Inhibitor Concentration is Related to Biochemical Parameters of Follicular Development

1983 ◽  
Vol 29 (5) ◽  
pp. 1105-1113 ◽  
Author(s):  
P. M. Sluss ◽  
P. W. Fletcher ◽  
L. E. Reichert
Keyword(s):  
Molecular Weight ◽  
Follicular Fluid ◽  
Biochemical Parameters ◽  
Follicle Stimulating Hormone ◽  
Follicular Development ◽  
Weight Fraction ◽  
Low Molecular Weight ◽  
Inhibitor Concentration ◽  
Hormone Binding ◽  
Stimulating Hormone

EFFECT OF SUPPRESSION OF THE SURGE OF FOLLICLE-STIMULATING HORMONE WITH PORCINE FOLLICULAR FLUID ON FOLLICULAR DEVELOPMENT IN THE RAT

1981 ◽  
Vol 88 (1) ◽  
pp. 67-71 ◽  
Author(s):  
ANNE N. HIRSHFIELD ◽  
L. V. DE PAOLO
Keyword(s):  
Follicular Fluid ◽  
Follicle Stimulating Hormone ◽  
Follicular Development ◽  
Oestrous Cycle ◽  
Subsequent Cycle ◽  
Stimulating Hormone

To examine the manner in which the FSH surge of one oestrous cycle recruits follicles for ovulation in the subsequent cycle, porcine follicular fluid (PFF) was used to alter the pattern of endogenous FSH secretion during the periovulatory period. Ovaries of animals killed at oestrus or metoestrus were examined histologically for the presence of large follicles (greater than 400 μm in diameter) after treatment. Large follicles were absent in ovaries of all PFF-treated animals at oestrus, while control rats had an average of 2·7 large follicles per ovary. By metoestrus, however, ovaries of rats treated with PFF contained several large, healthy follicles. Only when PFF treatment was continued throughout the evening of oestrus was the appearance of large follicles prevented at metoestrus. Our results suggest that the prolonged oestrous portion of the FSH surge, rather than the pro-oestrous portion, is responsible for follicular recruitment during the normal oestrous cycle in the rat. They also indicate that compensatory follicular development occurs in response to the FSH rebound which has been shown to follow FSH suppression.

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