scholarly journals Kinetics and thermodynamics of ligand binding by cytochrome P450 3A4 and relevance to substrate cooperativity

2006 ◽  
Vol 20 (4) ◽  
Author(s):  
Emre Mehmet Isin ◽  
F. Peter Guengerich
Keyword(s):  
Cytochrome P450 ◽  
Ligand Binding ◽  
Cytochrome P450 3A4 ◽  
Kinetics And Thermodynamics

Elucidation of Distinct Ligand Binding Sites for Cytochrome P450 3A4†

Biochemistry ◽  
2000 ◽  
Vol 39 (20) ◽  
pp. 5929-5939 ◽  
Author(s):  
Natilie A. Hosea ◽  
Grover P. Miller ◽  
F. Peter Guengerich
Keyword(s):  
Cytochrome P450 ◽  
Ligand Binding ◽  
Binding Sites ◽  
Cytochrome P450 3A4 ◽  
Ligand Binding Sites

scholarly journals Ligand Binding to Cytochrome P450 3A4 in Phospholipid Bilayer Nanodiscs

2007 ◽  
Vol 282 (39) ◽  
pp. 28309-28320 ◽  
Author(s):  
Abhinav Nath ◽  
Yelena V. Grinkova ◽  
Stephen G. Sligar ◽  
William M. Atkins
Keyword(s):  
Cytochrome P450 ◽  
Ligand Binding ◽  
Phospholipid Bilayer ◽  
Cytochrome P450 3A4

The Thermodynamic Landscape of Testosterone Binding to Cytochrome P450 3A4:  Ligand Binding and Spin State Equilibria†

Biochemistry ◽  
2005 ◽  
Vol 44 (4) ◽  
pp. 1353-1366 ◽  
Author(s):  
Arthur G. Roberts ◽  
A. Patricia Campbell ◽  
William M. Atkins
Keyword(s):  
Cytochrome P450 ◽  
Ligand Binding ◽  
Spin State ◽  
Cytochrome P450 3A4

scholarly journals Peripheral Ligand Binding and Allostery in Cytochrome P450 3A4

2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Dmitri R Davydov ◽  
Jessica A. O. Rumfeldt ◽  
Elena V Sineva ◽  
Nadezhda Y. Davydova ◽  
James R. Halpert
Keyword(s):  
Cytochrome P450 ◽  
Ligand Binding ◽  
Cytochrome P450 3A4

scholarly journals Conformational Response of N-Terminally Truncated Cytochrome P450 3A4 to Ligand Binding in Solution

Biochemistry ◽  
2019 ◽  
Vol 58 (37) ◽  
pp. 3903-3910 ◽  
Author(s):  
Shih-Wei Chuo ◽  
Shu-Hao Liou ◽  
Lee-Ping Wang ◽  
R. David Britt ◽  
Thomas L. Poulos ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Ligand Binding ◽  
Cytochrome P450 3A4

scholarly journals Peripheral Ligand-binding Site in Cytochrome P450 3A4 Located with Fluorescence Resonance Energy Transfer (FRET)

2011 ◽  
Vol 287 (9) ◽  
pp. 6797-6809 ◽  
Author(s):  
Dmitri R. Davydov ◽  
Jessica A. O. Rumfeldt ◽  
Elena V. Sineva ◽  
Harshica Fernando ◽  
Nadezhda Y. Davydova ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Energy Transfer ◽  
Ligand Binding ◽  
Binding Site ◽  
Fluorescence Resonance Energy Transfer ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Cytochrome P450 3A4 ◽  
Ligand Binding Site ◽  
Fluorescence Resonance
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