Providing Authentic Research Opportunities In A Large Laboratory Course By Studying Metabolic Channeling Properties Of Malate Dehydrogenase Isoforms In Trypanosoma Brucei

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Amy Springer
Keyword(s):  
Trypanosoma Brucei ◽  
Malate Dehydrogenase ◽  
Metabolic Channeling ◽  
Laboratory Course ◽  
Research Opportunities

Sequencing and heterologous expression of a cytosolic-type malate dehydrogenase of Trypanosoma brucei

2001 ◽  
Vol 117 (2) ◽  
pp. 217-221 ◽  
Author(s):  
Javier Vernal ◽  
Jorge Muñoz-Jordán ◽  
Miklós Müller ◽  
Juan José Cazzulo ◽  
Cristina Nowicki
Keyword(s):  
Heterologous Expression ◽  
Trypanosoma Brucei ◽  
Malate Dehydrogenase

The malate dehydrogenase isoforms from Trypanosoma brucei: Subcellular localization and differential expression in bloodstream and procyclic forms

2006 ◽  
Vol 36 (3) ◽  
pp. 295-307 ◽  
Author(s):  
Alejandro Aranda ◽  
Dante Maugeri ◽  
Antonio D. Uttaro ◽  
Fred Opperdoes ◽  
Juan. J. Cazzulo ◽  
...  
Keyword(s):  
Subcellular Localization ◽  
Differential Expression ◽  
Trypanosoma Brucei ◽  
Malate Dehydrogenase

Scanning Tunneling Microscopy and Atomic Force Microscopy of Enzymes and Enzyme Complexes

1990 ◽  
Vol 48 (3) ◽  
pp. 174-175
Author(s):  
Ronald D. Edstrom ◽  
Xiuru Yang ◽  
Mary E. Gurnack ◽  
Marcia A. Miller ◽  
Rui Yang ◽  
...  
Keyword(s):  
Cell Biology ◽  
Inorganic Ions ◽  
Bulk Liquid ◽  
Soluble Form ◽  
Scanning Tunneling ◽  
Tunneling Microscopy ◽  
Metabolic Channeling ◽  
Simplistic Notion ◽  
Soluble Enzymes

Many of the questions in biochemistry and cell biology are concerned with the relationships of proteins and other macromolecules in complex arrays which are responsible for carrying out metabolic sequences. The simplistic notion that the enzymes we isolate in soluble form from the cytoplasm were also soluble in vivo is being replaced by the concept that these enzymes occur in organized systems within the cell. In this newer view, the cytoplasm is organized and the “soluble enzymes” are in fact fixed in the cellular space and the only soluble components of the cell are small metabolites, inorganic ions etc. Further support for the concept of metabolic organization is provided by the evidence of metabolic channeling. It has been shown that for some metabolic pathways, the intermediates are not in free diffusion equilibrium with the bulk liquid in the cell but are passed along, more or less directly, from one enzyme to the next.

Complementary laboratory course in cariology

1996 ◽  
Vol 60 (6) ◽  
pp. 533-535
Author(s):  
D Steinberg ◽  
Z Hirschfeld
Keyword(s):  
Laboratory Course

Light-activation of NADP-malate dehydrogenase: A highly controlled process for an optimized function

2000 ◽  
Vol 110 (3) ◽  
pp. 322-329 ◽  
Author(s):  
M. Miginiac-Maslow ◽  
K. Johansson ◽  
E. Ruelland ◽  
E. Issakidis-Bourguet ◽  
I. Schepens ◽  
...  
Keyword(s):  
Malate Dehydrogenase ◽  
Light Activation
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