scholarly journals Divergent myofibrillar protein synthesis and signalling in skeletal muscle in response to light and heavy resistance exercise loading

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Lars Holm ◽  
Gerrit Hall ◽  
Adam J Rose ◽  
Simon Doessing ◽  
Erik A Richter ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Protein Synthesis ◽  
Resistance Exercise ◽  
Myofibrillar Protein ◽  
Heavy Resistance Exercise ◽  
Myofibrillar Protein Synthesis

scholarly journals Skeletal muscle IL-15/IL-15Rα and myofibrillar protein synthesis after resistance exercise

2017 ◽  
Vol 28 (1) ◽  
pp. 116-125 ◽  
Author(s):  
A. Pérez-López ◽  
J. McKendry ◽  
M. Martin-Rincon ◽  
D. Morales-Alamo ◽  
B. Pérez-Köhler ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Protein Synthesis ◽  
Resistance Exercise ◽  
Myofibrillar Protein ◽  
Myofibrillar Protein Synthesis

scholarly journals Even effect of milk protein and carbohydrate intake but no further effect of heavy resistance exercise on myofibrillar protein synthesis in older men

2018 ◽  
Vol 58 (2) ◽  
pp. 583-595 ◽  
Author(s):  
Søren Reitelseder ◽  
Kasper Dideriksen ◽  
Jakob Agergaard ◽  
Nikolaj M. Malmgaard-Clausen ◽  
Rasmus L. Bechshoeft ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Resistance Exercise ◽  
Milk Protein ◽  
Older Men ◽  
Myofibrillar Protein ◽  
Carbohydrate Intake ◽  
Heavy Resistance Exercise ◽  
Myofibrillar Protein Synthesis

scholarly journals Daily Myofibrillar Protein Synthesis Rates in Response to Low- and High-Frequency Resistance Exercise Training in Healthy, Young Men

2020 ◽  
pp. 1-8
Author(s):  
Brandon J. Shad ◽  
Janice L. Thompson ◽  
James Mckendry ◽  
Andrew M. Holwerda ◽  
Yasir S. Elhassan ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Protein Synthesis ◽  
Exercise Training ◽  
Resistance Exercise ◽  
High Frequency ◽  
Young Men ◽  
Myofibrillar Protein ◽  
Resistance Exercise Training ◽  
Repetition Maximum ◽  
Myofibrillar Protein Synthesis

The impact of resistance exercise frequency on muscle protein synthesis rates remains unknown. The aim of this study was to compare daily myofibrillar protein synthesis rates over a 7-day period of low-frequency (LF) versus high-frequency (HF) resistance exercise training. Nine young men (21 ± 2 years) completed a 7-day period of habitual physical activity (BASAL). This was followed by a 7-day exercise period of volume-matched, LF (10 × 10 repetitions at 70% one-repetition maximum, once per week) or HF (2 × 10 repetitions at ∼70% one-repetition maximum, five times per week) resistance exercise training. The participants had one leg randomly allocated to LF and the other to HF. Skeletal muscle biopsies and daily saliva samples were collected to determine myofibrillar protein synthesis rates using 2H2O, with intracellular signaling determined using Western blotting. The myofibrillar protein synthesis rates did not differ between the LF (1.46 ± 0.26%/day) and HF (1.48 ± 0.33%/day) conditions over the 7-day exercise training period (p > .05). There were no significant differences between the LF and HF conditions over the first 2 days (1.45 ± 0.41%/day vs. 1.25 ± 0.46%/day) or last 5 days (1.47 ± 0.30%/day vs. 1.50 ± 0.41%/day) of the exercise training period (p > .05). Daily myofibrillar protein synthesis rates were not different from BASAL at any time point during LF or HF (p > .05). The phosphorylation status and total protein content of selected proteins implicated in skeletal muscle ribosomal biogenesis were not different between conditions (p > .05). Under the conditions of the present study, resistance exercise training frequency did not modulate daily myofibrillar protein synthesis rates in young men.

scholarly journals Rapid aminoacidemia enhances myofibrillar protein synthesis and anabolic intramuscular signaling responses after resistance exercise

2011 ◽  
Vol 94 (3) ◽  
pp. 795-803 ◽  
Author(s):  
D. W. West ◽  
N. A. Burd ◽  
V. G. Coffey ◽  
S. K. Baker ◽  
L. M. Burke ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Resistance Exercise ◽  
Myofibrillar Protein ◽  
Myofibrillar Protein Synthesis

scholarly journals Improved recovery from skeletal muscle damage is largely unexplained by myofibrillar protein synthesis or inflammatory and regenerative gene expression pathways

2020 ◽  
Author(s):  
George Frederick Pavis ◽  
Tom SO Jameson ◽  
Marlou L. Dirks ◽  
Benjamin P. Lee ◽  
Doaa Reda Abdelrahman ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Protein Synthesis ◽  
Muscle Damage ◽  
Muscle Function ◽  
Nutritional Intervention ◽  
Myofibrillar Protein ◽  
Skeletal Muscle Damage ◽  
Amino Acid Availability ◽  
Expression Pathways ◽  
Myofibrillar Protein Synthesis

The contribution of myofibrillar protein synthesis (MyoPS) to recovery from skeletal muscle damage in humans is unknown. Recreationally active males and females consumed a daily protein-polyphenol beverage targeted at increasing amino acid availability and reducing inflammation (PPB; n=9), both known to affect MyoPS, or an isocaloric placebo (PLA; n=9) during 168 h of recovery from 300 maximal unilateral eccentric contractions (EE). Muscle function was assessed daily. Muscle biopsies were collected 24, 27, 36, 72 and 168 h for MyoPS measurements using 2H2O and expression of 224 genes using RT-qPCR and pathway analysis. PPB improved recovery of muscle function, which was impaired for five days following EE in PLA (interaction; P<0.05). Acute postprandial MyoPS rates were unaffected by nutritional intervention (24-27 h). EE increased overnight (27-36 h) MyoPS versus control leg (PLA: 33±19%; PPB: 79±25%; leg P<0.01), and PPB tended to increase this further (interaction P=0.06). Daily MyoPS rates were greater with PPB between 72-168 h after EE, albeit after function had recovered. Inflammatory and regenerative signaling pathways were dramatically upregulated and clustered following EE but were unaffected by nutritional intervention. These results suggest that accelerated recovery from EE is not explained by elevated MyoPS or suppression of inflammation.

scholarly journals Altered anabolic signalling and reduced stimulation of myofibrillar protein synthesis after feeding and resistance exercise in people with obesity

2018 ◽  
Vol 596 (21) ◽  
pp. 5119-5133 ◽  
Author(s):  
Joseph W. Beals ◽  
Sarah K. Skinner ◽  
Colleen F. McKenna ◽  
Elizabeth G. Poozhikunnel ◽  
Samee A. Farooqi ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Resistance Exercise ◽  
Myofibrillar Protein ◽  
Anabolic Signalling ◽  
Myofibrillar Protein Synthesis ◽  
Stimulation Of

scholarly journals Fish oil supplementation suppresses resistance exercise and feeding-induced increases in anabolic signaling without affecting myofibrillar protein synthesis in young men

2016 ◽  
Vol 4 (6) ◽  
pp. e12715 ◽  
Author(s):  
Chris McGlory ◽  
Sophie L. Wardle ◽  
Lindsay S. Macnaughton ◽  
Oliver C. Witard ◽  
Fraser Scott ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Fish Oil ◽  
Resistance Exercise ◽  
Young Men ◽  
Myofibrillar Protein ◽  
Fish Oil Supplementation ◽  
Myofibrillar Protein Synthesis

scholarly journals Myofibrillar protein synthesis following ingestion of soy protein isolate at rest and after resistance exercise in elderly men

2012 ◽  
Vol 9 (1) ◽  
pp. 57 ◽  
Author(s):  
Yifan Yang ◽  
Tyler A Churchward-Venne ◽  
Nicholas A Burd ◽  
Leigh Breen ◽  
Mark A Tarnopolsky ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Resistance Exercise ◽  
Soy Protein ◽  
Soy Protein Isolate ◽  
Protein Isolate ◽  
Myofibrillar Protein ◽  
Elderly Men ◽  
Myofibrillar Protein Synthesis
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