scholarly journals Fish oil supplementation suppresses resistance exercise and feeding-induced increases in anabolic signaling without affecting myofibrillar protein synthesis in young men

2016 ◽  
Vol 4 (6) ◽  
pp. e12715 ◽  
Author(s):  
Chris McGlory ◽  
Sophie L. Wardle ◽  
Lindsay S. Macnaughton ◽  
Oliver C. Witard ◽  
Fraser Scott ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Fish Oil ◽  
Resistance Exercise ◽  
Young Men ◽  
Myofibrillar Protein ◽  
Fish Oil Supplementation ◽  
Myofibrillar Protein Synthesis

scholarly journals Enhanced Amino Acid Sensitivity of Myofibrillar Protein Synthesis Persists for up to 24 h after Resistance Exercise in Young Men

2011 ◽  
Vol 141 (4) ◽  
pp. 568-573 ◽  
Author(s):  
Nicholas A. Burd ◽  
Daniel W. D. West ◽  
Daniel R. Moore ◽  
Philip J. Atherton ◽  
Aaron W. Staples ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Amino Acid ◽  
Resistance Exercise ◽  
Young Men ◽  
Myofibrillar Protein ◽  
Acid Sensitivity ◽  
Myofibrillar Protein Synthesis

scholarly journals Daily Myofibrillar Protein Synthesis Rates in Response to Low- and High-Frequency Resistance Exercise Training in Healthy, Young Men

2020 ◽  
pp. 1-8
Author(s):  
Brandon J. Shad ◽  
Janice L. Thompson ◽  
James Mckendry ◽  
Andrew M. Holwerda ◽  
Yasir S. Elhassan ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Protein Synthesis ◽  
Exercise Training ◽  
Resistance Exercise ◽  
High Frequency ◽  
Young Men ◽  
Myofibrillar Protein ◽  
Resistance Exercise Training ◽  
Repetition Maximum ◽  
Myofibrillar Protein Synthesis

The impact of resistance exercise frequency on muscle protein synthesis rates remains unknown. The aim of this study was to compare daily myofibrillar protein synthesis rates over a 7-day period of low-frequency (LF) versus high-frequency (HF) resistance exercise training. Nine young men (21 ± 2 years) completed a 7-day period of habitual physical activity (BASAL). This was followed by a 7-day exercise period of volume-matched, LF (10 × 10 repetitions at 70% one-repetition maximum, once per week) or HF (2 × 10 repetitions at ∼70% one-repetition maximum, five times per week) resistance exercise training. The participants had one leg randomly allocated to LF and the other to HF. Skeletal muscle biopsies and daily saliva samples were collected to determine myofibrillar protein synthesis rates using 2H2O, with intracellular signaling determined using Western blotting. The myofibrillar protein synthesis rates did not differ between the LF (1.46 ± 0.26%/day) and HF (1.48 ± 0.33%/day) conditions over the 7-day exercise training period (p > .05). There were no significant differences between the LF and HF conditions over the first 2 days (1.45 ± 0.41%/day vs. 1.25 ± 0.46%/day) or last 5 days (1.47 ± 0.30%/day vs. 1.50 ± 0.41%/day) of the exercise training period (p > .05). Daily myofibrillar protein synthesis rates were not different from BASAL at any time point during LF or HF (p > .05). The phosphorylation status and total protein content of selected proteins implicated in skeletal muscle ribosomal biogenesis were not different between conditions (p > .05). Under the conditions of the present study, resistance exercise training frequency did not modulate daily myofibrillar protein synthesis rates in young men.

scholarly journals Resistance exercise volume affects myofibrillar protein synthesis and anabolic signalling molecule phosphorylation in young men

2010 ◽  
Vol 588 (16) ◽  
pp. 3119-3130 ◽  
Author(s):  
Nicholas A. Burd ◽  
Andrew M. Holwerda ◽  
Keegan C. Selby ◽  
Daniel W. D. West ◽  
Aaron W. Staples ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Resistance Exercise ◽  
Young Men ◽  
Myofibrillar Protein ◽  
Signalling Molecule ◽  
Anabolic Signalling ◽  
Myofibrillar Protein Synthesis

scholarly journals Rapid aminoacidemia enhances myofibrillar protein synthesis and anabolic intramuscular signaling responses after resistance exercise

2011 ◽  
Vol 94 (3) ◽  
pp. 795-803 ◽  
Author(s):  
D. W. West ◽  
N. A. Burd ◽  
V. G. Coffey ◽  
S. K. Baker ◽  
L. M. Burke ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Resistance Exercise ◽  
Myofibrillar Protein ◽  
Myofibrillar Protein Synthesis

Impact of Short-term Sedentariness on Week-to-Week Myofibrillar Protein Synthesis Rates in Physically Active Young Men

2018 ◽  
Vol 50 (5S) ◽  
pp. 370
Author(s):  
Brandon J. Shad ◽  
Andrew M. Holwerda ◽  
Yasir S. Elhassan ◽  
Luc J.C. van Loon ◽  
Janice L. Thompson ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Young Men ◽  
Myofibrillar Protein ◽  
Short Term ◽  
Physically Active ◽  
Myofibrillar Protein Synthesis

scholarly journals Altered anabolic signalling and reduced stimulation of myofibrillar protein synthesis after feeding and resistance exercise in people with obesity

2018 ◽  
Vol 596 (21) ◽  
pp. 5119-5133 ◽  
Author(s):  
Joseph W. Beals ◽  
Sarah K. Skinner ◽  
Colleen F. McKenna ◽  
Elizabeth G. Poozhikunnel ◽  
Samee A. Farooqi ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Resistance Exercise ◽  
Myofibrillar Protein ◽  
Anabolic Signalling ◽  
Myofibrillar Protein Synthesis ◽  
Stimulation Of

scholarly journals Short-term muscle disuse induces a rapid and sustained decline in daily myofibrillar protein synthesis rates

2020 ◽  
Vol 318 (2) ◽  
pp. E117-E130 ◽  
Author(s):  
Sean P. Kilroe ◽  
Jonathan Fulford ◽  
Andrew M. Holwerda ◽  
Sarah R. Jackman ◽  
Benjamin P. Lee ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Young Men ◽  
Myofibrillar Protein ◽  
Deuterated Water ◽  
Short Term ◽  
Muscle Disuse ◽  
Before And After ◽  
Mri Scans ◽  
The Impact ◽  
Myofibrillar Protein Synthesis

Short-term muscle disuse has been reported to lower both postabsorptive and postprandial myofibrillar protein synthesis rates. This study assessed the impact of disuse on daily myofibrillar protein synthesis rates following short-term (2 and 7 days) muscle disuse under free living conditions. Thirteen healthy young men (age: 20 ± 1 yr; BMI: 23 ± 1 kg/m−2) underwent 7 days of unilateral leg immobilization via a knee brace, with the nonimmobilized leg acting as a control. Four days before immobilization participants ingested 400 mL of 70% deuterated water, with 50-mL doses consumed daily thereafter. Upper leg bilateral MRI scans and muscle biopsies were collected before and after 2 and 7 days of immobilization to determine quadriceps volume and daily myofibrillar protein synthesis rates. Immobilization reduced quadriceps volume in the immobilized leg by 1.7 ± 0.3 and 6.7 ± 0.6% after 2 and 7 days, respectively, with no changes in the control leg. Over the 1-wk immobilization period, myofibrillar protein synthesis rates were 36 ± 4% lower in the immobilized (0.81 ± 0.04%/day) compared with the control (1.26 ± 0.04%/day) leg ( P < 0.001). Myofibrillar protein synthesis rates in the control leg did not change over time ( P = 0.775), but in the immobilized leg they were numerically lower during the 0- to 2-day period (16 ± 6%, 1.11 ± 0.09%/day, P = 0.153) and were significantly lower during the 2- to 7-day period (44 ± 5%, 0.70 ± 0.06%/day, P < 0.001) when compared with the control leg. We conclude that 1 wk of muscle disuse induces a rapid and sustained decline in daily myofibrillar protein synthesis rates in healthy young men.

scholarly journals One Week of Step Reduction Lowers Myofibrillar Protein Synthesis Rates in Young Men

2019 ◽  
Vol 51 (10) ◽  
pp. 2125-2134 ◽  
Author(s):  
BRANDON J. SHAD ◽  
JANICE L. THOMPSON ◽  
ANDREW M. HOLWERDA ◽  
BEN STOCKS ◽  
YASIR S. ELHASSAN ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Young Men ◽  
Myofibrillar Protein ◽  
Myofibrillar Protein Synthesis

scholarly journals Myofibrillar protein synthesis following ingestion of soy protein isolate at rest and after resistance exercise in elderly men

2012 ◽  
Vol 9 (1) ◽  
pp. 57 ◽  
Author(s):  
Yifan Yang ◽  
Tyler A Churchward-Venne ◽  
Nicholas A Burd ◽  
Leigh Breen ◽  
Mark A Tarnopolsky ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Resistance Exercise ◽  
Soy Protein ◽  
Soy Protein Isolate ◽  
Protein Isolate ◽  
Myofibrillar Protein ◽  
Elderly Men ◽  
Myofibrillar Protein Synthesis
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