A small‐molecule inhibitor of macrophage migration inhibitory factor for the treatment of inflammatory disease

Inflammatory Disease ◽

Small Molecule Inhibitor ◽

Inhibitory Factor ◽

Macrophage Migration ◽

Molecule Inhibitor

A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activity

Journal of Biological Chemistry ◽

10.1074/jbc.ra119.009860 ◽

2019 ◽

Vol 294 (49) ◽

pp. 18522-18531 ◽

Cited By ~ 5

Author(s):

Pathricia Veronica Tilstam ◽

Georgios Pantouris ◽

Michael Corman ◽

Monica Andreoli ◽

Keyvan Mahboubi ◽

...

Keyword(s):

Biological Activity ◽

Small Molecule ◽

Small Molecule Inhibitor ◽

Inhibitory Factor ◽

Macrophage Migration ◽

Molecule Inhibitor

Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009 ◽

Regulating in Vitro Motility of Human Mesenchymal Stem Cells with Macrophage Migration Inhibitory Factor (MIF) and a Small-Molecule MIF Antagonist

10.1007/978-94-007-0884-6_26 ◽

2011 ◽

pp. 149-160

Author(s):

Kim C. O’Connor ◽

Bonnie L. Barrilleaux ◽

Donald G. Phinney ◽

Benjamin W. Fischer-Valuck ◽

Katie C. Russell ◽

...

Keyword(s):

Stem Cells ◽

Mesenchymal Stem Cells ◽

Small Molecule ◽

Human Mesenchymal Stem Cells ◽

Inhibitory Factor ◽

Macrophage Migration ◽

In Vitro Motility

A Small-Molecule Macrophage Migration Inhibitory Factor Antagonist Protects against Glomerulonephritis in Lupus-Prone NZB/NZW F1 and MRL/lpr Mice

The Journal of Immunology ◽

10.4049/jimmunol.1001767 ◽

2010 ◽

Vol 186 (1) ◽

pp. 527-538 ◽

Cited By ~ 97

Author(s):

Lin Leng ◽

Liang Chen ◽

Juan Fan ◽

Dorothee Greven ◽

Alvaro Arjona ◽

...

Keyword(s):

Small Molecule ◽

Inhibitory Factor ◽

Macrophage Migration ◽

Factor Antagonist

SMALL MOLECULE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) ARE BENEFICIAL DURING SEPSIS

Shock ◽

10.1097/00024382-200606001-00076 ◽

2006 ◽

Vol 25 (Supplement 1) ◽

pp. 25

Author(s):

Y. Al-Abed ◽

K.F. Cheng ◽

D. Dabideen ◽

B. Aljabari ◽

V. A. Pavlov ◽

...

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Inhibitory Factor ◽

Macrophage Migration

The small molecule macrophage migration inhibitory factor antagonist MIF098, inhibits pulmonary hypertension associated with murine SLE

International Immunopharmacology ◽

10.1016/j.intimp.2019.105874 ◽

2019 ◽

Vol 76 ◽

pp. 105874 ◽

Cited By ~ 1

Author(s):

Huijing Huang ◽

Dandan Chen ◽

Jun Pu ◽

Ancai Yuan ◽

Qiong Fu ◽

...

Keyword(s):

Pulmonary Hypertension ◽

Small Molecule ◽

Inhibitory Factor ◽

Macrophage Migration ◽

Factor Antagonist

New therapeutic target in inflammatory disease: macrophage migration inhibitory factor

Internal Medicine Journal ◽

10.1111/j.1445-5994.2005.00853.x ◽

2005 ◽

Vol 35 (7) ◽

pp. 419-426 ◽

Cited By ~ 74

Author(s):

E. F. Morand

Keyword(s):

Inflammatory Disease ◽

Therapeutic Target ◽

Inhibitory Factor ◽

Macrophage Migration

Macrophage migration inhibitory factor: a regulator of glucocorticoid activity with a critical role in inflammatory disease

Molecular Medicine Today ◽

10.1016/s1357-4310(97)01133-7 ◽

1997 ◽

Vol 3 (11) ◽

pp. 502-507 ◽

Cited By ~ 80

Author(s):

Seamas C. Donnelly ◽

Richard Bucala

Keyword(s):

Inflammatory Disease ◽

Critical Role ◽

Inhibitory Factor ◽

Macrophage Migration

Small-molecule inhibitors of macrophage migration inhibitory factor (MIF) as an emerging class of therapeutics for immune disorders

Drug Discovery Today ◽

10.1016/j.drudis.2018.06.017 ◽

2018 ◽

Vol 23 (11) ◽

pp. 1910-1918 ◽

Cited By ~ 16

Author(s):

Tjie Kok ◽

Anna A. Wasiel ◽

Robbert H. Cool ◽

Barbro N. Melgert ◽

Gerrit J. Poelarends ◽

...

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Inhibitory Factor ◽

Macrophage Migration ◽

Immune Disorders

Advances and Insights for Small Molecule Inhibition of Macrophage Migration Inhibitory Factor

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.8b00589 ◽

2018 ◽

Vol 61 (18) ◽

pp. 8104-8119 ◽

Cited By ~ 13

Author(s):

Vinay Trivedi-Parmar ◽

William L. Jorgensen

Keyword(s):

Small Molecule ◽

Inhibition Of Macrophage Migration

Inhibitory Factor ◽

Macrophage Migration ◽

Small Molecule Inhibition ◽

56: Substance P-Induced Expression of CD74 (Receptor for Macrophage Migration Inhibitory Factor) on the cell Surface of Urothelial cells in vivo

The Journal of Urology ◽

10.1016/s0022-5347(18)30321-5 ◽

2007 ◽

Vol 177 (4S) ◽

pp. 19-19

Author(s):

Katherine L. Meyer-Siegler ◽

Pedro L. Vera

Keyword(s):

Substance P ◽

Cell Surface ◽

Inhibitory Factor ◽

Macrophage Migration ◽

Urothelial Cells ◽

Induced Expression