Postoperative Bleeding After Coronary Artery Bypass Surgery with Cardiopulmonary Bypass

2002 ◽  
Vol 95 (5) ◽  
pp. 1466
Author(s):  
Philip R. Belcher ◽  
Elijah W. Muriithi
Perfusion ◽  
2010 ◽  
Vol 25 (2) ◽  
pp. 65-70 ◽  
Author(s):  
Simo-Pekka Koivisto ◽  
Jan-Ola Wistbacka ◽  
Riikka Rimpiläinen ◽  
Juha Nissinen ◽  
Pertti Loponen ◽  
...  

2003 ◽  
Vol 11 (3) ◽  
pp. 198-202 ◽  
Author(s):  
Minxin Wei ◽  
Jari Laurikka ◽  
Pekka Kuukasjärvi ◽  
Erkki Pehkonen ◽  
Matti Tarkka

Plasma levels of sE-selectin, sP-selectin, and sICAM-1 were measured before anesthesia and at 0.5, 4, and 20 hours after cardiopulmonary bypass in 37 men undergoing coronary artery bypass surgery. Plasma sE-selectin remained close to the preoperative levels. The levels of sP-selectin increased significantly from 46.5 ± 15.3 ng·mL−1 to 69.3 ± 39.6 ng·mL−1 at 0.5 hours, 84.1 ± 45.5 ng·mL−1 at 4 hours, and 79.6 ± 35.5 ng·mL−1 at 20 hours. Plasma sICAM-1 levels decreased 0.5 hours after cardiopulmonary bypass, recovered at 4 hours, and showed a significant increase at 20 hours. The changes in plasma levels of adhesion molecules did not correlate with the duration of bypass or aortic crossclamping, hemodynamics, or creatine kinase-MB levels. However, sE-selectin and sICAM-1 levels increased considerably more in patients who needed norepinephrine in the intensive care unit. These results indicate that the transient changes in plasma levels of soluble adhesion molecules are not associated with postoperative myocardial injury in low-risk coronary grafting, although they correlate with the need for a vasopressor.


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