The pharmacology of non-steroidal anti-inflammatory drugs for acute pain

1995 ◽  
Vol 8 (5) ◽  
pp. 461-468 ◽  
Author(s):  
Jane C. Ballantyne ◽  
Mark Dershwitz
2019 ◽  
Vol 139 (12) ◽  
pp. 1601-1608
Author(s):  
Yoshitaka Saito ◽  
Takehiro Yamada ◽  
Masaki Kobayashi ◽  
Jun Sakakibara-Konishi ◽  
Naofumi Shinagawa ◽  
...  

2015 ◽  
Vol 20 (6) ◽  
pp. 300-304 ◽  
Author(s):  
Jennifer LC Wilson ◽  
Patricia A Poulin ◽  
Robert Sikorski ◽  
Howard J Nathan ◽  
Monica Taljaard ◽  
...  

OBJECTIVES: To determine whether the prevalence of opioid use among patients requiring elective same-day admission (SDA) surgery is greater than the 2.5% prevalence found in the general population. Secondary objectives were to assess compliance with expert recommendations on acute pain management in opioid-tolerant patients and to examine clinical outcomes.METHODS: A retrospective review of 812 systematically sampled adult SDA surgical cases between April 1, 2008 and March 31, 2009 was conducted.RESULTS: Among 798 eligible patients, 148 (18.5% [95% CI 15.9% to 21.2%]) were prescribed opioids, with 4.4% prescribed long-acting opioids (95% CI 3.0% to 5.8%). Use of opioids was most prevalent among orthopedic and neurosurgery patients. Among the 35 patients on long-acting opioids who had a high likelihood of being tolerant, anesthesiologists correctly identified 33, but only 13 (37%) took their usual opioid preoperatively while 22 (63%) had opioids continued postoperatively. Acetaminophen, nonsteroidal anti-inflammatory drugs and pregabalin were ordered preoperatively in 18 (51%), 15 (43%) and 18 (51%) cases, respectively, while ketamine was used in 15 (43%) patients intraoperatively. Acetaminophen, nonsteroidal anti-inflammatory drugs and pregabalin were ordered postoperatively in 31 (89%), 15 (43%) and 17 (49%) of the cases, respectively. No differences in length of stay, readmissions and emergency room visits were found between opioid-tolerant and opioid-naïve patients.CONCLUSION: Opioid use is more common in SDA surgical patients than in the general population and is most prevalent within orthopedic and neurosurgery patients. Uptake of expert opinion on the management of acute pain in the opioid tolerant patient population is lacking.


Pain ◽  
2006 ◽  
Vol 121 (1) ◽  
pp. 22-28 ◽  
Author(s):  
Hugo F. Miranda ◽  
Margarita M. Puig ◽  
Juan Carlos Prieto ◽  
Gianni Pinardi

2021 ◽  
Vol 9 (C) ◽  
pp. 239-242
Author(s):  
Siti Salima ◽  
Ali Budi Harsono ◽  
Aisyah Aisyah ◽  
Kemala Mantilidewi

BACKGROUND: One of the harshest side effects following anticancer agent treatments is chemotherapy-induced neuropathic pain. After surgical staging, chemotherapy combination of paclitaxel carboplatin could be a choice of therapy for Stage II or more advanced stage of ovarian cancer. Different side effects may appear after the application of paclitaxel. CASE REPORT: Here, we show an uncommon case of paclitaxel-acute pain syndrome (P-APS), and how we deal with such cases according to our experiences. One uncommon side effect is P-APS, which can be treated effectively with the administration of non-steroidal anti-inflammatory drugs, corticosteroid, and supportive therapy. CONCLUSION: One uncommon side effect of Paclitaxel induced neuropathic can be treated effectively with the administration of non-steroidal anti inflammatory drugs, corticosteroid, and supportive therapy.


1999 ◽  
Vol 6 (2_suppl) ◽  
pp. 5-9 ◽  
Author(s):  
Donald R. Mehlisch ◽  
Joseph Markenson ◽  
Thomas J. Schnitzer

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