CRITICAL CARE RESOURCE UTILIZATION AND LONG-TERM OUTCOME IN THE “EXTREMELY” INJURED (ISS≥50)

A range of hormonal manipulations have been proposed as adjunctive therapy during critical care. These therapies might be used to treat a pre-existing or acquired hormonal disorder. Additionally, hormonal manipulation has been suggested to alter the long-term outcome of critical illness, even in patients without structural abnormalities of endocrine glands. Currently, the effectiveness of these anabolic therapies has not been established and they might be harmful in some patient groups. Recently, it has been recognized that many critically-ill patients have low levels of vitamin D and this is associated with an adverse outcome. It is still unclear whether replacement of vitamin D will be effective in improving outcome. This chapter will also highlight the importance of recognizing and addressing hormonal deficiency in patients with known pituitary disease and with traumatic brain injury (TBI). TBI is associated with a high prevalence of acute and long-term pituitary dysfunction. The management of the rare, but important thyroid disorders requiring critical care, thyroid storm, and myxoedema coma, will also be discussed.

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Prediction of long-term outcome subtypes in ARDS: first steps towards personalised medicine in critical care

Thorax ◽

10.1136/thoraxjnl-2017-210775 ◽

2017 ◽

Vol 72 (12) ◽

pp. 1067-1068

Author(s):

Nicola Latronico ◽

Cosetta Minelli ◽

Matthias Eikermann

Keyword(s):

Critical Care ◽

Personalised Medicine ◽

Term Outcome ◽

Long Term Outcome

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Long-Term Outcome Following Tracheostomy in Critical Care

Critical Care Medicine ◽

10.1097/ccm.0000000000001382 ◽

2016 ◽

Vol 44 (3) ◽

pp. 617-628 ◽

Cited By ~ 20

Author(s):

Ged A. Dempsey ◽

Ben Morton ◽

Clare Hammell ◽

Lisa T. Williams ◽

Catrin Tudur Smith ◽

...

Keyword(s):

Critical Care ◽

Term Outcome ◽

Long Term Outcome

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Long-term Outcome Following Tracheostomy in Critical Care

Survey of Anesthesiology ◽

10.1097/01.sa.0000504589.32822.55 ◽

2016 ◽

Vol 60 (6) ◽

pp. 230-231

Author(s):

Ged A. Dempsey ◽

Ben Morton ◽

Clare Hammell ◽

Lisa T. Williams ◽

Catrin Tudur Smith ◽

...

Keyword(s):

Critical Care ◽

Term Outcome ◽

Long Term Outcome

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452: LONG-TERM OUTCOME OF PATIENTS WITH SOLID TUMORS FOLLOWING NONSURGICAL CRITICAL CARE ADMISSION

Critical Care Medicine ◽

10.1097/01.ccm.0000528470.74184.56 ◽

2018 ◽

Vol 46 (1) ◽

pp. 210-210

Author(s):

Katherine Murphy ◽

Phil Haji-Michael

Keyword(s):

Critical Care ◽

Solid Tumors ◽

Term Outcome ◽

Long Term Outcome ◽

Critical Care Admission

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In This Issue

Critical Care and Resuscitation ◽

10.51893/2020.4.iti ◽

2020 ◽

Vol 23 (4) ◽

pp. 291-292

Author(s):

Rinaldo Bellomo

Keyword(s):

Critical Care ◽

Organ Donation ◽

Time Pressure ◽

Care Practice ◽

Term Outcome ◽

Long Term Outcome ◽

Donation Process ◽

The Family ◽

Key Aspects

This issue of Critical Care and Resuscitation focuses on several key aspects of modern intensive care unit (ICU) practice in Australia and New Zealand. Organ donation is particularly prominent, with two original articles and a dedicatededitorial. 1, 2, 3 The first article provides strong evidence that, in more difficult organ donation family conversations (ie, when there is no evidence of organ donation registry presence and organ donation is not raised by the family), the likelihood of successful donation is significantly increased by such conversation being led by an organ donation specialist. As supported by the editorial, it is increasingly clear that in this field, like all other aspects of critical care practice, training and specialisation make a difference. The second article demonstrates that organ donation can be successfully achieved under time pressure, even for highly vasopressor-dependent donors, and with good long term outcome when applying an expedited organ donation process. The implications are clear.

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