New method of volume effect calculation in clinical practice

2013 ◽  
Vol 30 ◽  
pp. 73-73
Author(s):  
V. Subbotin ◽  
A. Bukarev ◽  
A. Sitnikov ◽  
A. Malahova ◽  
V. Demidova ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Volume Effect ◽  
New Method

scholarly journals Improved Specificity of a New Homogeneous Assay for LDL-Cholesterol in Serum with Abnormal Lipoproteins

2006 ◽  
Vol 52 (5) ◽  
pp. 886-888 ◽  
Author(s):  
Yasumasa Iwasaki ◽  
Hiroyuki Matsuyama ◽  
Nobuo Nakashima
Keyword(s):  
Clinical Practice ◽  
Obstructive Jaundice ◽  
Ldl Cholesterol ◽  
Performance Characteristics ◽  
New Method ◽  
Assay Performance ◽  
Basic Performance ◽  
Homogeneous Method ◽  
Homogeneous Assay ◽  
Improved Performance

Abstract Background: Although a homogeneous assay for serum LDL-cholesterol (LDL-C) has become a routine clinical procedure, problems remain in assay performance characteristics. Methods: We examined the performance of a recently developed automated homogeneous assay (New-Daiichi assay) for serum LDL-C and compared the results with those obtained by the current homogeneous method (Denka-Seiken assay) or by ultracentrifugation as a control. Results: The New-Daiichi assay showed satisfactory basic performance characteristics such as reproducibility, linearity, and stability. There was no interference in the assay by various substances examined. The LDL-C values obtained with this method correlated well with those obtained by ultracentrifugation. In samples from patients with obstructive jaundice, both methods detected cholesterol from abnormal lipoproteins (such as lipoprotein-X and -Y), but the New-Daiichi assay was less reactive and more specific for LDL-C. Conclusion: The new method has improved performance for the accurate measurement of LDL-C in clinical practice.

scholarly journals Applying a new method for studying the functional state of hemostasis in clinical practice

Critical Care ◽  
2011 ◽  
Vol 15 (S1) ◽  
Author(s):  
O Tarabrin ◽  
I Tyutrin ◽  
S Kalinchuk ◽  
A Turenko ◽  
S Shcherbakov ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Functional State ◽  
New Method

scholarly journals Myocardial Work by Echocardiography: Principles and Applications in Clinical Practice

2021 ◽  
Vol 10 (19) ◽  
pp. 4521
Author(s):  
Federica Ilardi ◽  
Antonello D’Andrea ◽  
Flavio D’Ascenzi ◽  
Francesco Bandera ◽  
Giovanni Benfari ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Current Knowledge ◽  
Systolic Function ◽  
Global Longitudinal Strain ◽  
Left Ventricular ◽  
New Method ◽  
Added Value ◽  
Non Invasive ◽  
Potential Applications ◽  
Lv Systolic Function

Left ventricular (LV) global longitudinal strain (GLS) has established itself in the last decade as a reliable, more objective method for the evaluation of LV systolic function, able to detect subtle abnormalities in LV contraction even in the presence of preserved ejection fraction (EF). However, recent studies have demonstrated that GLS, similar to LV EF, has important load dependency. Non-invasive myocardial work (MW) quantification has emerged in the last years as an alternative tool for myocardial function assessment. This new method, incorporating measurement of strain and LV pressure, has shown to overcome GLS and LV EF limitations and provide a loading-independent evaluation of myocardial performance. The presence of a commercially available echocardiographic software for the non-invasive MW calculation has allowed the application of this new method in different settings. This review sought to provide an overview on the current knowledge of non-invasive MW estimation, showing its potential applications and possible added value in clinical practice.

scholarly journals OPTIMIZING COVID-19 VACCINE USAGE

2021 ◽  
Author(s):  
Carlos Poblete Jara ◽  
Lício A. Velloso ◽  
Eliana Pereira de Araújo
Keyword(s):  
Clinical Practice ◽  
Dead Space ◽  
Multiple Dose ◽  
Volume Effect ◽  
Filling Process ◽  
Multiple Points ◽  
Vaccination Protocol ◽  
Process Technique

ABSTRACTAs the worldwide vaccination, it is imperative to minimize vaccine wastage by effectively using all doses available. Vaccine wastage can occur at multiple points during the vaccination process, but it is mainly because the device dead space and the filling process technique. However, there are no studies discussing the waste volume effect of COVID-19 vaccines in clinical practice. There is an increasing COVID-19 vaccine demand that we estimate up to several billion dual doses. The objective of this study was to assess the number of 0.3mL doses obtained from a multiple-dose vial using 1ml and 3ml syringes with different type of needles replicating the first COVID-19 vaccination protocol.Our results suggest that it is possible to obtain six or seven doses from each vial instead five. We provide evidence to optimize between 20% and 40% additional vaccine doses per vial if the current 5-dose vials are used, making scarce supplies go further.It is our duty, as researchers, to ensure the efficacy and efficiency of the worldwide COVID-19 vaccination process. However, if standard syringes-needles and technique are used, there may not be sufficient volume to draw extra doses from a single vial.

The Bone Scan in Clinical Practice

1980 ◽  
Vol 25 (1) ◽  
pp. 45-49 ◽  
Author(s):  
I. Fogelman ◽  
I. T. Boyle
Keyword(s):  
Clinical Practice ◽  
Bone Scan ◽  
Clinical Importance ◽  
Relative Sensitivity ◽  
New Method ◽  
Bone Scanning ◽  
Technetium 99M ◽  
Bone Uptake

Radioisotopic bone scanning using technetium-99m labelled phosphate and diphosphonate compounds is a relatively new method of imaging the skeleton which has rapidly assumed major clinical importance. In this review the pathophysiology of bone uptake of radiopharmaceutical, the relative sensitivity of bone scan and radiograph, and the more important uses of bone scanning in clinical practice are described.

scholarly journals New technologies and trends of prenatal diagnostics

2017 ◽  
Vol 66 (2) ◽  
pp. 33-39 ◽  
Author(s):  
Tatyana K Kascheeva ◽  
Tatyana V Kuznetzova ◽  
Vladislav S Baranov
Keyword(s):  
Clinical Practice ◽  
New Technologies ◽  
Prenatal Testing ◽  
European Countries ◽  
New Method ◽  
Prenatal Diagnostics ◽  
Chromosomal Anomalies ◽  
Noninvasive Prenatal Testing ◽  
Material Supply ◽  
Management Problems

Advantages and drawbacks of noninvasive prenatal testing (NIPT) of chromosomal anomalies are briefly reviewed. Material supply, employment issues, financial and management problems in European countries and in Russia are discussed. Many problems are rising under implementation of this new method into the clinical practice.

scholarly journals A new method to calculate the maximum dose of local anesthetics

2020 ◽  
Vol 9 (3) ◽  
Author(s):  
Julierme Ferreira Rocha ◽  
Song Fan ◽  
Eduardo Dias Ribeiro
Keyword(s):  
Clinical Practice ◽  
Local Anesthesia ◽  
Local Anesthetics ◽  
Maximum Dose ◽  
Drug Dosage ◽  
New Method ◽  
Recommended Dose ◽  
Dosage Calculation ◽  
Drug Dosage Calculation

The purpose of this correspondence is to present a suggestion of a simple and practical formula to calculate the maximum recommended dose of local anesthetics. We believe that using the proposed formula, it will be easier to calculate the maximum recommended dose.Descriptors: : Local Anesthetics; Drug Dosage Calculation; Clinical Practice Pattern.ReferencesMalamed SF. Handbook of local anesthesia. 6th ed. St Louis: Mosby  2013.

Development of a device to determine the stiffness of elastic garments and bandages

2011 ◽  
Vol 26 (7) ◽  
pp. 285-291 ◽  
Author(s):  
M Hirai ◽  
K Niimi ◽  
K Miyazaki ◽  
H Iwata ◽  
I Sugimoto ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Initial Pressure ◽  
New Method ◽  
Compression Stocking ◽  
Interface Pressure ◽  
Compression Pressure ◽  
Elastic Compression ◽  
Elastic Stockings

Objective To evaluate the reliability of a newly developed stiffness-determining device, composed of a leg mannequin and air-pack type analyser, for measuring the interface pressure. Method The correlation of stiffness values obtained employing the Hohenstein method and this new method was investigated using 17 different brands of medical elastic compression stocking. Results A significant correlation in stiffness values using the two methods was obtained ( P < 0.01). When this new method was applied to the bandages, the stiffness was significantly correlated with the initial pressure when assessing both short-stretch and long-stretch bandages. On the comparison of stiffness values between elastic stockings and bandages with the same initial pressure, the short-stretch bandages showed a predominantly higher value than long-stretch bandages and stockings ( P < 0.01). Conclusion The reliability of this new method, which can be easily applied to not only elastic stockings but also elastic bandages, was verified. In clinical practice, the compression pressure should be selected in consideration of the prospective stiffness.

Sign in / Sign up

Export Citation Format

Share Document