INDEXATION OF LEFT VENTRICULAR MASS, PREVALENCE OF LEFT VENTRICULAR HYPERTROPHY AND PREDICTIVE ROLE OF BLOOD PRESSURE

2004 ◽  
Vol 22 (Suppl. 2) ◽  
pp. S93
Author(s):  
L. A. Ferrara ◽  
O. Vaccaro ◽  
O. Cardoni ◽  
M. Mancini ◽  
A. Zanchetti
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Asdiana Nur ◽  
Fransiska Lintong ◽  
Maya Moningka

Abstract: Left ventricular hypertrophy (LVH) is target organ damage of cardiac with high prevalence in patients with hypertension. Increase of left ventricular mass was caused by increase in wall thickness as compensatory mechanism to minimize wall stress in response to elevated blood pressure. Left Ventricular Mass Index (LVMI) is one of echocardiography parameters used to diagnose LVH. The purpose of this study is to know the correlation between blood pressure and LVMI in patients with hypertension. A cross sectional study was performed at Cardiac Vascular and Brain Centre/ Central General Hospital of Prof. Dr. R. D Kandou. Sample was determined with consecutive sampling. Blood pressure of subjects were measurement and LVMI were taken from medical record. Data were analyzed used SPSS 21. Fifty one subjects, including 34 subjects with adequate blood pressure control and 17 subjects with inadequate blood pressure control are enrolled with ≥60 years old and men (64.7%) mostly found in this study. Pearson Correlation Test found a positive and significant correlation between systolic blood pressure and LVMI (r=0.488;p<0.05) while Spearman Correlation Test found a positive but not significant correlation between diastolic blood pressure and LVMI (r=0.226;p>0.05). In conclusion, there is a positive correlation between blood pressure and LVMI in patients with hypertension but a significant correlation was just found between systolic blood pressure and LVMI.Keywords: hypertension, Left ventricular hypertrophy (LVH), blood pressure, echocardiography, left ventricular mass index (LVMI)Abstrak: Hipertrofi ventrikel kiri (Left Ventricular Hypertrophy= LVH) merupakan kerusakan target organ jantung dengan prevalensi yang tinggi pada penderita hipertensi. Peningkatan massa ventrikel kiri disebabkan oleh penebalan dinding ventrikel kiri sebagai mekanisme kompensasi untuk meminimalkan tegangan dinding akibat respon terhadap peningkatan tekanan darah. Indeks massa ventrikel kiri (Left Ventricular Mass Index= LVMI) merupakan salah satu parameter ekokardiografi yang digunakan dalam mendiagnosa LVH. Tujuan dari penelitian ini adalah mengetahui korelasi antara tekanan darah dan LVMI pada penderita hipertensi. Penelitian dengan desain potong lintang dilakukan di instalasi pusat jantung dan pembuluh darah RSUP Prof Dr. R. D. Kandou. Sampel ditentukan secara consecutive sampling. Pengukuran tekanan darah dilakukan pada subyek penelitian dan LVMI diperoleh dari rekam medik. Data dianalisa menggunakan SPSS 21. Sebanyak 51 subyek penelitian, termasuk 34 subyek dengan hipertensi terkontrol dan 17 subyek dengan hipertensi tidak terkontrol, terdaftar pada penelitian ini dengan usia ≥60 tahun (39,2%) dan pria (64,7%)paling banyak ditemukan.Uji Korelasi Pearson menemukan tekanan darah sistolik mempunyai korelasi positif dan signifikan dengan LVMI (r=0,488;p<0,05) sedangkan uji Korelasi Spearman menemukan korelasi yang positif namun tidak signifikan antara tekanan darah diastolik dan LVMI (r=0,226;p>0,05). kesimpulan dari penelitian ini adalah terdapat korelasi positif antara tekanan darah dan LVMI pada penderita hipertensi, namun hubungan yang signifikan hanya ditemukan antara tekanan darah sistolik dan LVMI.Kata Kunci : hipertensi, hipertrofi ventrikel kiri, tekanan darah, ekokardiografi, indeks massa ventrikel kiri


Heart ◽  
2009 ◽  
Vol 96 (2) ◽  
pp. 148-152 ◽  
Author(s):  
H J Simpson ◽  
S J Gandy ◽  
J G Houston ◽  
N S Rajendra ◽  
J I Davies ◽  
...  

2004 ◽  
pp. 65-71 ◽  
Author(s):  
J Svartberg ◽  
D von Muhlen ◽  
H Schirmer ◽  
E Barrett-Connor ◽  
J Sundfjord ◽  
...  

OBJECTIVE: To test the hypothesis that lower endogenous testosterone levels are associated with higher blood pressure, left ventricular mass, and left ventricular hypertrophy. DESIGN: Population-based cross-sectional study. METHODS: Sex hormone levels, measured by immunoassay, anthropometric measurements and resting blood pressure were studied in 1548 men aged 25-84 Years; echocardiography was completed in 1264 of these men. Partial correlations and multiple regressions were used to estimate the associations between sex hormones, blood pressure and left ventricular mass by height. Analyses of variance and covariance were used to compare men with categorical hypertension and left ventricular hypertrophy. RESULTS: In age-adjusted partial correlations, total testosterone and sex hormone-binding globulin (SHBG) were each inversely associated with systolic blood pressure (SBP) (P<0.001). Men with categorical hypertension (SBP> or =140 or diastolic blood pressure (DBP)> or =90 mmHg) had lower levels of total and free testosterone and SHBG before (P<0.001, P=0.011 and P<0.001, respectively) and after (P<0.001, P=0.035 and P=0.002, respectively) adjusting for body mass index (BMI). Total testosterone and SHBG were each inversely associated with left ventricular mass (P<0.001), and men with left ventricular hypertrophy had significantly lower levels of total testosterone (P=0.042) and SHBG (P=0.006); these associations were no longer significant after adjusting for BMI. CONCLUSION: The results of the present study are consistent with the hypothesis that lower levels of testosterone in men are associated with higher blood pressure, left ventricular mass, and left ventricular hypertrophy. The reduced associations after adjusting for BMI suggest that the association of low testosterone levels with blood pressure and left ventricular mass is mediated by obesity.


VASA ◽  
2013 ◽  
Vol 42 (4) ◽  
pp. 284-291 ◽  
Author(s):  
Seong-Woo Choi ◽  
Hye-Yeon Kim ◽  
Hye-Ran Ahn ◽  
Young-Hoon Lee ◽  
Sun-Seog Kweon ◽  
...  

Background: To investigate the association between ankle-brachial index (ABI), left ventricular hypertrophy (LVH) and left ventricular mass index (LVMI) in a general population. Patients and methods: The study population consisted of 8,246 people aged 50 years and older who participated in the baseline survey of the Dong-gu Study conducted in Korea between 2007 and 2010. Trained research technicians measured LV mass using mode M ultrasound echocardiography and ABI using an oscillometric method. Results: After adjustment for risk factors and common carotid artery intima-media thickness (CCA-IMT) and the number of plaques, higher ABIs (1.10 1.19, 1.20 - 1.29, and ≥ 1.30) were significantly and linearly associated with high LVMI (1.10 - 1.19 ABI: β, 3.33; 95 % CI, 1.72 - 4.93; 1.20 - 1.29 ABI: β, 6.51; 95 % CI, 4.02 - 9.00; ≥ 1.30 ABI: β, 14.83; 95 % CI, 6.18 - 23.48). An ABI of 1.10 - 1.19 and 1.20 - 1.29 ABI was significantly associated with LVH (1.10 - 1.19 ABI: OR, 1.35; 95 % CI, 1.19 - 1.53; 1.20 - 1.29 ABI: OR, 1.59; 95 % CI, 1.31 - 1.92) and ABI ≥ 1.30 was marginally associated with LVH (OR, 1.73; 95 % CI, 0.93 - 3.22, p = 0.078). Conclusions: After adjustment for other cardiovascular variables and CCA-IMT and the number of plaques, higher ABIs are associated with LVH and LVMI in Koreans aged 50 years and older.


2020 ◽  
Vol 73 (5) ◽  
pp. 943-946
Author(s):  
Olha M. Chernatska ◽  
Liudmyla N. Prystupa ◽  
Hanna A. Fadieieva ◽  
Alina V. Liashenko ◽  
Yuliia O. Smiianova

The aim is the analysis of hyperuricemia influence on the heart features in patients with arterial hypertension. Materials and methods: We include 75 patients with arterial hypertension which were divided in two groups according to the level of uric acid in the blood, 30 practically healthy people. Patients from the I group (n = 40) had arterial hypertension and coexistent hyperuricemia; ІІ (n = 35) – arterial hypertension. Left ventricular mass index was determined for left ventricular hypertrophy confirmation. We used clinical, anthropometric, biochemical, instrumental, statistical method. Serum uric acid level was observed by the reaction with uricase. Left ventricular mass index was calculated as left ventricular mass to body surface area ratio. The results were analyzed statistically by SPSS 21 and Graphpad. Results: Left ventricular mass index was significantly higher (р = 0,0498) in patients from the І group (109,7 ± 3,21) g/m2 comparable with the ІІ (97,6 ± 5,35) g/m2 and increased in proportion to the biggest level of uric acid (r = 0,31; p = 0,04) in patients with arterial hypertension and hyperuricemia. Conclusions: Concentric and excentric left ventricular hypertrophy, increased left ventricular mass index proportionally to uric acid levels (r = 0,31; p = 0,04) is the confirmation of important role of hyperuricemia in the left ventricular hypertrophy development in patients with arterial hypertension.


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