IgA Endomysium Antibodies on Human Umbilical Cord: An Excellent Diagnostic Tool for Celiac Disease in Childhood

1997 ◽  
Vol 24 (5) ◽  
pp. 563-567 ◽  
Author(s):  
Kaija-Leena Kolho ◽  
Erkki Savilahti
Keyword(s):  
Celiac Disease ◽  
Umbilical Cord ◽  
Diagnostic Tool ◽  
Human Umbilical Cord ◽  
Endomysium Antibodies

scholarly journals Diagnostic value of various serum antibodies detected by diverse methods in childhood celiac disease

1996 ◽  
Vol 42 (11) ◽  
pp. 1838-1842 ◽  
Author(s):  
L Sacchetti ◽  
A Ferrajolo ◽  
G Salerno ◽  
P Esposito ◽  
M M Lofrano ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Celiac Disease ◽  
Umbilical Cord ◽  
Diagnostic Value ◽  
Diagnostic Sensitivity ◽  
Antibody Detection ◽  
Human Umbilical Cord ◽  
Iga Antibody ◽  
Monkey Esophagus ◽  
Gliadin Antibody

Abstract The diagnostic performances of antiendomysium IgA detected on monkey esophagus and human umbilical cord smooth muscle, of antireticulin IgA, and of antigliadin IgA and IgG were calculated in 74 children with celiac disease (CD) or other gastrointestinal disorders. We also compared four methods for gliadin antibody detection. With a diagnostic specificity of 100%, diagnostic sensitivity was 94% for antireticulin IgA, 93% for antiendomysium IgA when detected on human umbilical cord smooth muscle, and 97% when detected on monkey esophagus. The diagnostic sensitivity for gliadin antibody was highest with an ELISA procedure, followed by fluorogenic detection (94% for IgG, 91% for IgA, 97% with IgA and IgG combined). Because of its high diagnostic sensitivity and ease and speed of use, the combined antigliadin IgG and IgA antibody assay is suitable for screening large groups of patients. In IgG- or IgA-positive cases, the more demanding and more specific antiendomysium IgA evaluation is required to confirm suspected CD.

IgA anti-endomysial antibodies on human umbilical cord tissue for celiac disease screening

1995 ◽  
Vol 40 (9) ◽  
pp. 1902-1905 ◽  
Author(s):  
Umberto Volta ◽  
Nicolino Molinaro ◽  
Lucia De Franceschi ◽  
Domenico Fratangelo ◽  
Francesco Bianco Bianchi
Keyword(s):  
Celiac Disease ◽  
Umbilical Cord ◽  
Disease Screening ◽  
Human Umbilical Cord ◽  
Umbilical Cord Tissue ◽  
Endomysial Antibodies

IgA antiendomysium antibodies in human umbilical cord sections as a screening test in relatives of patients with celiac disease

Allergy ◽  
1997 ◽  
Vol 52 (10) ◽  
pp. 1017-1021 ◽  
Author(s):  
M. Bagnasco ◽  
P. Montagna ◽  
A. Alessandri ◽  
E. Castellano ◽  
G. P. Pesce ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Umbilical Cord ◽  
Screening Test ◽  
Human Umbilical Cord ◽  
Antiendomysium Antibodies
Sign in / Sign up

Export Citation Format

Share Document