Stage Specific Identification of the Expression of GnRH mRNA and Localization of the GnRH Receptor in Mature Rat and Adult Human Testis

1995 ◽  
pp. 1958-1961 ◽  
Author(s):  
Jong Yoon Bahk ◽  
Jae Seog Hyun ◽  
Seung Hwa Chung ◽  
Hyun Lee ◽  
Myeong Ok Kim ◽  
...  
Keyword(s):  
Gnrh Receptor ◽  
Human Testis ◽  
Specific Identification ◽  
Adult Human

Stage Specific Identification of the Expression of GnRH mRNA and Localization of the GnRH Receptor in Mature Rat and Adult Human Testis

1995 ◽  
Vol 154 (5) ◽  
pp. 1958-1961 ◽  
Author(s):  
Jong Yoon Bahk ◽  
Jae Seog Hyun ◽  
Seung Hwa Chung ◽  
Hyun Lee ◽  
Myeong Ok Kim ◽  
...  
Keyword(s):  
Gnrh Receptor ◽  
Human Testis ◽  
Specific Identification ◽  
Adult Human

scholarly journals Stage-specific Localization and Expression of c-kit in the Adult Human Testis

2009 ◽  
Vol 57 (9) ◽  
pp. 861-869 ◽  
Author(s):  
Sreepoorna K. Unni ◽  
Deepak N. Modi ◽  
Shilpa G. Pathak ◽  
Jayesh V. Dhabalia ◽  
Deepa Bhartiya
Keyword(s):  
Current Knowledge ◽  
Protein Localization ◽  
Immunohistochemical Analysis ◽  
Human Testis ◽  
Specific Expression ◽  
Adult Human ◽  
Kit Receptor ◽  
Specific Localization ◽  
Human Spermatogenesis ◽  
And Function

The c-kit receptor (KIT) and its ligand, stem cell factor (SCF), represent one of the key regulators of testicular formation, development, and function and have been extensively studied in various animal models. The present study was undertaken to characterize the pattern of localization and expression of c-kit in normal adult human testis. Immunohistochemical analysis showed that KIT is expressed in the cytoplasm of spermatogonia, acrosomal granules of spermatids, and Leydig cells. Interestingly, a rather heterogenous pattern of expression of the protein along the basement membrane was observed. Intense protein localization in spermatogonia was detected in stages I–III, whereas low expression was observed in stages IV–VI of the seminiferous epithelium, indicating that the expression of the molecule was stage specific. In situ hybridization studies revealed that the transcripts of the gene were also localized in a similar non-uniform pattern. To the best of our knowledge, such a stage-specific expression of KIT has not been reported previously in the human testis. The results of the present study may expand current knowledge about the c-kit/SCF system in human spermatogenesis.

scholarly journals The adult human testis transcriptional cell atlas

Cell Research ◽  
2018 ◽  
Vol 28 (12) ◽  
pp. 1141-1157 ◽  
Author(s):  
Jingtao Guo ◽  
Edward J. Grow ◽  
Hana Mlcochova ◽  
Geoffrey J. Maher ◽  
Cecilia Lindskog ◽  
...  
Keyword(s):  
Human Testis ◽  
Adult Human

scholarly journals ERβ1 and the ERβ2 Splice Variant (ERβcx/β2) Are Expressed in Distinct Cell Populations in the Adult Human Testis

2002 ◽  
Vol 87 (6) ◽  
pp. 2706-2715 ◽  
Author(s):  
Philippa T. K. Saunders ◽  
Michael R. Millar ◽  
Sheila Macpherson ◽  
D. Stewart Irvine ◽  
Nigel P. Groome ◽  
...  
Keyword(s):  
Splice Variant ◽  
Human Testis ◽  
Cell Populations ◽  
Adult Human ◽  
Distinct Cell
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