THE ROLE OF HUMORAL AND CELLULAR RESPONSES IN THE FORMATION OF NEOINTIMAL FIBROPLASIA AFTER PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY

1990 ◽  
Vol 83 (Supplement) ◽  
pp. 2S-69
Author(s):  
Timothy V. Myers ◽  
Fong Y. Tsai ◽  
Dipak C. Shah ◽  
Mark E. Myers
1995 ◽  
Vol 25 (2) ◽  
pp. 380A
Author(s):  
Alfredo E. Rodríguez ◽  
Mario Fernández ◽  
Eduardo Mele ◽  
Ernesto Peyregne ◽  
Néstor A. Pérez Baliño

2001 ◽  
Vol 8 (5) ◽  
pp. 477-483 ◽  
Author(s):  
Martin Schillinger ◽  
Markus Haumer ◽  
Gerald Schlerka ◽  
Wolfgang Mlekusch ◽  
Markus Exner ◽  
...  

2003 ◽  
Vol 10 (2) ◽  
pp. 298-303 ◽  
Author(s):  
Kevin J. Molloy ◽  
Akhtar Nasim ◽  
Nick J.M. London ◽  
A. Ross Naylor ◽  
Peter R.F. Bell ◽  
...  

Purpose: To assess the role of percutaneous transluminal angioplasty (PTA) to treat critical limb ischemia (CLI) and to relate the changing experience with endovascular treatment of this condition in a major vascular unit. Methods: A prospective study was performed involving 110 consecutive patients (57 women; mean age 76 years, range 57–99) undergoing balloon angioplasty for critical limb ischemia in 133 limbs. Outcome at 1 year was examined by case note review or questionnaire to determine survival, amputation-free survival, limb salvage, and CLI recurrence. Results: Technical success was achieved in 105 (79%) of 133 limbs; the overall complication rate was 20% (3.8% major, 16.2% minor). The median follow-up was 15 months (minimum 12). The 12-month limb salvage rate by life-table analysis was 88%. Patients with an initially successful angioplasty had an extremely good outcome (95% 1-year limb salvage). In contrast, the 28 patients with failed angioplasty fared very poorly; a major amputation was required in 10, and death occurred in another 9, leaving only 9 survivors with limbs intact at 1 year. Conclusions: The results of this study justify the continuing use of PTA as first-line treatment for critical limb ischemia.


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