Melphalan dosing regimens for management of recurrent melanoma by isolated limb perfusion: application of a physiological pharmacokinetic model based on melphalan distribution in the isolated perfused rat hindlimb

1997 ◽  
Vol 7 (3) ◽  
pp. 252-264 ◽  
Author(s):  
Z Y Wu ◽  
B M Smithers ◽  
M S Roberts
Keyword(s):  
Pharmacokinetic Model ◽  
Isolated Limb Perfusion ◽  
Model Based ◽  
Limb Perfusion ◽  
Dosing Regimens ◽  
Physiological Pharmacokinetic Model

Melphalan dosing-regimens for management of recurrent melanoma by isolated limb perfusion

1997 ◽  
Vol 7 (Supplement 1) ◽  
pp. S121
Author(s):  
Z Y Wu ◽  
B M Smithers ◽  
M S Roberts
Keyword(s):  
Isolated Limb Perfusion ◽  
Limb Perfusion ◽  
Dosing Regimens

Integration of Physicochemical and Pharmacokinetic Parameters in Lead Optimization: A Physiological Pharmacokinetic Model Based Approach

2010 ◽  
Vol 7 (3) ◽  
pp. 143-153 ◽  
Author(s):  
Elizabeth Hong-Geller ◽  
Sofiya Micheva-Viteva ◽  
Biju Benjamin ◽  
Tarani Kanta Barman ◽  
Tridib Chaira ◽  
...  
Keyword(s):  
Pharmacokinetic Model ◽  
Lead Optimization ◽  
Pharmacokinetic Parameters ◽  
Model Based ◽  
Physiological Pharmacokinetic Model

Repeat isolated limb perfusion with TNFα and melphalan for recurrent limb melanoma after failure of previous perfusion

2006 ◽  
Vol 32 (3) ◽  
pp. 318-324 ◽  
Author(s):  
E.M. Noorda ◽  
B.C. Vrouenraets ◽  
O.E. Nieweg ◽  
A.N. van Geel ◽  
A.M.M. Eggermont ◽  
...  
Keyword(s):  
Isolated Limb Perfusion ◽  
Limb Perfusion

Levels of natural IgM antibodies against phosphorylcholine in healthy individuals and in patients undergoing isolated limb perfusion

2004 ◽  
Vol 293 (1-2) ◽  
pp. 1-11 ◽  
Author(s):  
Niubel Diaz Padilla ◽  
Caroline Ciurana ◽  
Joep van Oers ◽  
Aernout C. Ogilvie ◽  
C. Erik Hack
Keyword(s):  
Isolated Limb Perfusion ◽  
Healthy Individuals ◽  
Igm Antibodies ◽  
Limb Perfusion ◽  
Natural Igm
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