GENDER-RELATED CARDIOVASCULAR RESPONSES TO COLD PRESSOR TEST IN NORMOTENSIVE SUBJECTS

1996 ◽  
Vol 3 (6) ◽  
pp. 419-422
Author(s):  
Mario Blanco ◽  
Ana Aleman ◽  
Ingrid Jelambi ◽  
Northan Hurtado ◽  
Tatiana Franco ◽  
...  
Keyword(s):  
Cold Pressor Test ◽  
Cold Pressor ◽  
Cardiovascular Responses ◽  
Pressor Test ◽  
Normotensive Subjects

scholarly journals Blunted cardiovascular responses to exercise in Parkinson’s disease patients: role of the muscle metaboreflex

2018 ◽  
Vol 120 (4) ◽  
pp. 1516-1524 ◽  
Author(s):  
Jeann L. Sabino-Carvalho ◽  
André L. Teixeira ◽  
Milena Samora ◽  
Maurício Daher ◽  
Lauro C. Vianna
Keyword(s):  
Blood Pressure ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cold Pressor Test ◽  
Peripheral Resistance ◽  
Cold Pressor ◽  
Cardiovascular Responses ◽  
Group Differences ◽  
Muscle Metaboreflex ◽  
Pressor Test

Patients with Parkinson’s disease (PD) exhibit attenuated cardiovascular responses to exercise. The underlying mechanisms that are potentially contributing to these impairments are not fully understood. Therefore, we sought to test the hypothesis that patients with PD exhibit blunted cardiovascular responses to isolated muscle metaboreflex activation following exercise. For this, mean blood pressure, cardiac output, and total peripheral resistance were measured using finger photoplethysmography and the Modelflow method in 11 patients with PD [66 ± 2 yr; Hoehn and Yahr score: 2 ± 1 a.u.; time since diagnosis: 7 ± 1 yr; means ± SD) and 9 age-matched controls (66 ± 3 yr). Measurements were obtained at rest, during isometric handgrip exercise performed at 40% maximal voluntary contraction, and during postexercise ischemia. Also, a cold pressor test was assessed to confirm that blunted cardiovascular responses were specific to exercise and not representative of generalized sympathetic responsiveness. Changes in mean blood pressure were attenuated in patients with PD during handgrip (PD: ∆25 ± 2 mmHg vs. controls: ∆31 ± 3 mmHg; P < 0.05), and these group differences remained during postexercise ischemia (∆17 ± 1 mmHg vs. ∆26 ± 1 mmHg, respectively; P < 0.01). Additionally, changes in total peripheral resistance were attenuated during exercise and postexercise ischemia, indicating blunted reflex vasoconstriction in patients with PD. Responses to cold pressor test did not differ between groups, suggesting no group differences in generalized sympathetic responsiveness. Our results support the concept that attenuated cardiovascular responses to exercise observed in patients with PD are, at least in part, explained by an altered skeletal muscle metaboreflex. NEW & NOTEWORTHY Patients with Parkinson’s disease (PD) presented blunted cardiovascular responses to exercise. We showed that cardiovascular response evoked by the metabolic component of the exercise pressor reflex is blunted in patients with PD. Furthermore, patients with PD presented similar pressor response during the cold pressor test compared with age-matched controls. Altogether, our results support the hypothesis that attenuated cardiovascular responses to exercise observed in patients with PD are mediate by an altered skeletal muscle metaboreflex.

Cardiovascular Responses to the Cold Pressor Test in Exercise-Trained and Untrained Men

1988 ◽  
Vol 8 (12) ◽  
pp. 518-524 ◽  
Author(s):  
Paul J. Rogers ◽  
Alfred A. Bove ◽  
Ray W. Squires ◽  
Kent R. Bailey
Keyword(s):  
Cold Pressor Test ◽  
Cold Pressor ◽  
Cardiovascular Responses ◽  
Pressor Test

Elevated Plasma Adrenaline Reflects Sympathetic Overactivity and Enhanced α-Adrenoceptor-Mediated Vasoconstriction in Essential Hypertension

1981 ◽  
Vol 61 (s7) ◽  
pp. 161s-164s ◽  
Author(s):  
P. Bolli ◽  
F. W. Amann ◽  
L. Hulthén ◽  
W. Kiowski ◽  
F. R. Bühler
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Blood Flow ◽  
Essential Hypertension ◽  
Forearm Blood Flow ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Plasma Adrenaline ◽  
Pressor Test ◽  
Normotensive Subjects

1. Stressful sympathetic stimulation (cold pressor test) was applied to 18 patients with essential hypertension and 15 normotensive subjects. Intra-arterial blood pressure, heart rate, plasma adrenaline and noradrenaline concentrations as well as forearm blood flow were measured before and during the cold pressor test; tests were repeated after regional postsynaptic α1-adrenoceptor blockade with prazosin. 2. Under basal conditions mean blood pressure (P &lt; 0.001), heart rate (P &lt; 0.01), forearm blood flow (P &lt; 0.001) as well as adrenaline concentration (P &lt; 0.01), but not noradrenaline, was higher in patients with essential hypertension. 3. During the cold pressor test, mean blood pressure, heart rate, plasma adrenaline and noradrenaline concentrations increased and forearm flow decreased (all P &lt; 0.001). 4. Stress-stimulated plasma adrenaline was higher in essential hypertensive patients than in normotensive subjects (P &lt; 0.01). In the former the stress-induced increase in plasma adrenaline correlated with the increase in mean blood pressure (r = 0.514; P &lt; 0.05). 5. Prazosin increased forearm blood flow more in essential hypertension (P &lt; 0.001). This increase correlated with the resting plasma adrenaline in the hypertensive (r = 0.710; P &lt; 0.001), but not in normotensive, subjects. 6. When the cold pressor test was repeated during postsynaptic α1-adrenoceptor blockade forearm blood flow did not decrease; instead it increased further in both groups (P &lt; 0.05). 7. Thus in essential hypertension elevated plasma adrenaline concentration reflects sympathetic overactivity as also expressed by enhanced α-adrenoceptor-mediated vasoconstriction.

scholarly journals Wave intensity, an index of ventriculo-arterial interaction, increases in hypertensive subjects but decreases in normotensive subjects during the cold pressor test

2021 ◽  
Author(s):  
Midori Tanaka ◽  
Motoaki Sugawara ◽  
Kiyomi Niki ◽  
Yasuo Ogasawara
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Reactivity ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Wave Intensity ◽  
Point Of View ◽  
Chi Square ◽  
Pressor Test ◽  
Ultrasonic Equipment ◽  
Normotensive Subjects

Abstract Purpose Cardiovascular reactivity to the cold pressor test (CPT) is considered to be a marker for apparent and potential hypertension. We aimed to elucidate the association between the changes in wave intensity (WI) during CPT and hypertension. Methods We recruited 85 volunteers, 33 of whom were hypertensive and 52 normotensive. Using ultrasonic equipment during CPT, we measured carotid arterial WI, which is defined in terms of blood pressure and velocity in the carotid artery. Results The peak WI (W1) increased during CPT in 70.6% of hypertensive individuals, but decreased in 72.6% of normotensive individuals. The chi-square (χ2) test showed that the association between the direction of change in W1 (increase or decrease) and the blood pressure (hypertensive or normotensive) was very strong (P < 0.0001). Conclusion Direction of change in W1 during CPT is a clear marker to discriminate cardiovascular reactivity that does not vary depending on each investigator’s subjective point of view.

scholarly journals Stress-induced cardiovascular responses to cold pressortest in healthy young subjects

2020 ◽  
Vol 10 (2) ◽  
pp. 182-188
Author(s):  
Valeri Nikolov ◽  
Miroslava Petkova ◽  
Emil Nikolov
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Reactivity ◽  
Sleep Disturbances ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Cardiovascular Responses ◽  
Aortic Pulse Wave Velocity ◽  
Applanation Tonometry ◽  
Pressor Test ◽  
Young Subjects

Hypertension is one of the leading diseases of the cardiovascular system. It is manifested by changes in arterial stiffness. Cardiovascular reactivity, especially blood pressure (BP), changes during the cold pressor test (CPT) depending on various factors. Undoubtedly, stress is one of the most important factors. The aim of this study is to investigate the various effects of CPT on cardiovascular responses in healthy young subjects. A total of 56 healthy individuals aged between 21 and 26 years were investigated. The cardiovascular responses (BP, heart rate and aortic pulse wave velocity) to CPT were recorded by using the applanation tonometry. The Medical Outcomes Study Sleep Scale and the State-Trait Anxiety Inventory were used. 32.14% (n = 18) of the individuals who showed differences in systolic BP more than 22 mm Hg and differences in diastolic BP more than 18 mm Hg after the CPT were defined as hyperreactors. Hyperreactors showed a significantly higher increase in sleep disturbances (p > 0.01) and anxiety when compared to normoreactors. The CPT used to diagnose cardiovascular reactivity in young individuals and the assessment of perceived stress can help identify candidates who are at risk of hypertonic disease in the future.   Keywords: Cold pressor test, cardiovascular reactivity, applanation tonometry, blood pressure, stress.

Pupillary and cardiovascular responses to the cold-pressor test

1995 ◽  
Vol 55 (1-2) ◽  
pp. 45-49 ◽  
Author(s):  
Cristina Tassorelli ◽  
Giuseppe Micieli ◽  
Vera Osipova ◽  
Francesco Rossi ◽  
Giuseppe Nappi
Keyword(s):  
Cold Pressor Test ◽  
Cold Pressor ◽  
Cardiovascular Responses ◽  
Pressor Test
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