Guar gum-based colon-specific drug delivery systems for the treatment of Inflammatory Bowel Diseases

2009 ◽  
Vol 15 ◽  
pp. S56
Author(s):  
S Yellela ◽  
S S ◽  
R YV
Keyword(s):  
Drug Delivery ◽  
Inflammatory Bowel Diseases ◽  
Drug Delivery Systems ◽  
Guar Gum ◽  
Delivery Systems ◽  
Specific Drug ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Colon Specific Drug Delivery

scholarly journals New Insights of Oral Colonic Drug Delivery Systems for Inflammatory Bowel Disease Therapy

2020 ◽  
Vol 21 (18) ◽  
pp. 6502
Author(s):  
Adrian H. Teruel ◽  
Isabel Gonzalez-Alvarez ◽  
Marival Bermejo ◽  
Virginia Merino ◽  
Maria Dolores Marcos ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Adverse Effects ◽  
Inflammatory Bowel Diseases ◽  
Drug Delivery Systems ◽  
Local Treatment ◽  
Delivery Systems ◽  
Colonic Drug Delivery ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Colonic Drug Delivery Systems (CDDS) are especially advantageous for local treatment of inflammatory bowel diseases (IBD). Site-targeted drug release allows to obtain a high drug concentration in injured tissues and less systemic adverse effects, as consequence of less/null drug absorption in small intestine. This review focused on the reported contributions in the last four years to improve the effectiveness of treatments of inflammatory bowel diseases. The work concludes that there has been an increase in the development of CDDS in which pH, specific enzymes, reactive oxygen species (ROS), or a combination of all of these triggers the release. These delivery systems demonstrated a therapeutic improvement with fewer adverse effects. Future perspectives to the treatment of this disease include the elucidation of molecular basis of IBD diseases in order to design more specific treatments, and the performance of more in vivo assays to validate the specificity and stability of the obtained systems.

Chronopharmaceutics Based Modern Colon Specific Drug Delivery Systems

2012 ◽  
Vol 9 (4) ◽  
pp. 311-318 ◽  
Author(s):  
Akanksha Tiwari ◽  
Raj Kumar Shukla ◽  
Suresh Tiwari ◽  
Surti Naazneen
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Specific Drug ◽  
Colon Specific Drug Delivery

Recent advances in colon-specific drug delivery systems

2018 ◽  
pp. 297-323
Author(s):  
Suryakanta Swain ◽  
Sitty Manohar Babu ◽  
Chinam Niranjan Patra ◽  
Muddana Eswara Rao
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Specific Drug ◽  
Recent Advances ◽  
Colon Specific Drug Delivery
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