ARTERIAL BLOOD GAS AND ACID-BASE DISORDERS IN INFANTS AND CHILDREN WITH STATUS ASTHMATICUS

1970 ◽  
Vol 14 (1) ◽  
pp. 66
Author(s):  
J. J. DOWNES ◽  
D. W. WOOD ◽  
T. W. STRIKER ◽  
J. C. PITTMAN
Keyword(s):  
Status Asthmaticus ◽  
Infants And Children ◽  
Blood Gas ◽  
Acid Base ◽  
Arterial Blood Gas ◽  
Arterial Blood ◽  
In Infants And Children

Arterial Blood Gas and Acid-Base Derangements in Children with Status Asthmaticus

1965 ◽  
Vol 26 (2) ◽  
pp. 245-245 ◽  
Author(s):  
JOHN DOWNES ◽  
DAVID WOOD ◽  
DAVID NIGHTINGALE ◽  
LEONARD BACHMAN
Keyword(s):  
Status Asthmaticus ◽  
Blood Gas ◽  
Acid Base ◽  
Arterial Blood Gas ◽  
Arterial Blood

ARTERIAL BLOOD GAS AND ACID-BASE DISORDERS IN INFANTS AND CHILDREN WITH STATUS ASTHMATICUS

PEDIATRICS ◽  
1968 ◽  
Vol 42 (2) ◽  
pp. 238-249
Author(s):  
John J. Downes ◽  
David W. Wood ◽  
Theodore W. Striker ◽  
Joffie C. Pittman
Keyword(s):  
Status Asthmaticus ◽  
Clinical Signs ◽  
Arterial Oxygen Tension ◽  
Base Deficit ◽  
Infants And Children ◽  
Clinical Severity ◽  
Arterial Oxygen ◽  
Acid Base ◽  
Arterial Blood ◽  
Arterial Ph

The course of arterial oxygen tension (Pao2), pH, carbon dioxide tension (Paco2) and base deficit (negative base excess) was studied in 45 episodes of status asthmaticus occurring in 32 infants and children. The data indicate that arterial hypoxemia occurs in these patients due to alveolar hypoventilation and pulmonary arterial-venous shunts. Three fourths of the patients tested demonstrated a base deficit which was related in part to ketonemia. The Paco2 varied from below normal to 168 mm Hg, and arterial pH varied from 6.89 to 7.41 at the time of peak clinical severity. Clinical signs of respiratory failure associated with a Paco2 above 65 mm Hg occurred in 13 patients (18 episodes), all of whom were successfully managed by mechanical ventilation. These studies indicate the variability in alveolar ventilation and acid-base balance during an asthmatic episode and the need for repeated assessment of arterial pH and blood gases if one is to provide optimal management.

A Practical Approach to Understanding Acid–Base Abnormalities in Critical Illness

2011 ◽  
Vol 24 (1) ◽  
pp. 17-26 ◽  
Author(s):  
Amy L. Dzierba ◽  
Prasad Abraham
Keyword(s):  
Critical Illness ◽  
Problem Solving ◽  
Critically Ill ◽  
Therapeutic Interventions ◽  
Practical Approach ◽  
Blood Gas ◽  
Acid Base ◽  
Arterial Blood Gas ◽  
Arterial Blood ◽  
Base Disorder

Acid−base disorders are common in the critically ill. Arterial blood gas (ABG) analysis is frequently used to identify and manage acid−base disturbances. Using a systematic problem-solving approach to acid−base disturbances will facilitate the identification and assess the progression and severity of the metabolic and respiratory abnormality. The intent of this review is to examine acid−base physiology and regulation, provide a method to evaluate a patient’s acid−base disorder, and provide therapeutic interventions.

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