scholarly journals 1379: THE INCIDENCE OF POST-INTUBATION HYPOTENSION AMONG ADULTS INTUBATED IN THE EMERGENCY DEPARTMENT

2021 ◽  
Vol 50 (1) ◽  
pp. 691-691
Author(s):  
Chloe Verwiel ◽  
Munish Goyal ◽  
Gail Drescher ◽  
Schuyler Gaillard ◽  
Jacqueline Barnes
2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Tadayoshi Ishimaru ◽  
◽  
Tadahiro Goto ◽  
Jin Takahashi ◽  
Hiroshi Okamoto ◽  
...  

AbstractTo determine whether ketamine use for tracheal intubation, compared to other sedative use, is associated with a lower risk of post-intubation hypotension in hemodynamically-unstable patients in the emergency department (ED), we analyzed the data of a prospective, multicenter, observational study—the second Japanese Emergency Airway Network (JEAN-2) Study—from February 2012 through November 2017. The current analysis included adult non-cardiac-arrest ED patients with a pre-intubation shock index of ≥0.9. The primary exposure was ketamine use as a sedative for intubation, with midazolam or propofol use as the reference. The primary outcome was post-intubation hypotension. A total of 977 patients was included in the current analysis. Overall, 24% of patients developed post-intubation hypotension. The ketamine group had a lower risk of post-intubation hypotension compared to the reference group (15% vs 29%, unadjusted odds ratio [OR] 0.45 [95% CI 0.31–0.66] p < 0.001). This association remained significant in the multivariable analysis (adjusted OR 0.43 [95% CI 0.28–0.64] p < 0.001). Likewise, in the propensity-score matching analysis, the patients with ketamine use also had a significantly lower risk of post-intubation hypotension (OR 0.47 [95% CI, 0.31–0.71] P < 0.001). Our observations support ketamine use as a safe sedative agent for intubation in hemodynamically-unstable patients in the ED.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Tadayoshi Ishimaru ◽  
◽  
Tadahiro Goto ◽  
Jin Takahashi ◽  
Hiroshi Okamoto ◽  
...  

CJEM ◽  
2019 ◽  
Vol 21 (S1) ◽  
pp. S80
Author(s):  
S. Freeman ◽  
M. Columbus ◽  
T. Nguyen ◽  
S. Mal ◽  
J. Yan

Introduction: Endotracheal intubation (ETI) is a lifesaving procedure commonly performed by emergency department (ED) physicians that may lead to patient discomfort or adverse events (e.g., unintended extubation) if sedation is inadequate. No ED-based sedation guidelines currently exist, so individual practice varies widely. This study's objective was to describe the self-reported post-ETI sedation practice of Canadian adult ED physicians. Methods: An anonymous, cross-sectional, web-based survey featuring 7 common ED scenarios requiring ETI was distributed to adult ED physician members of the Canadian Association of Emergency Physicians (CAEP). Scenarios included post-cardiac arrest, hypercapnic and hypoxic respiratory failure, status epilepticus, polytrauma, traumatic brain injury, and toxicology. Participants indicated first and second choice of sedative medication following ETI, as well as bolus vs. infusion administration in each scenario. Data was presented by descriptive statistics. Results: 207 (response rate 16.8%) ED physicians responded to the survey. Emergency medicine training of respondents included CCFP-EM (47.0%), FRCPC (35.8%), and CCFP (13.9%). 51.0% of respondents work primarily in academic/teaching hospitals and 40.4% work in community teaching hospitals. On average, responding physicians report providing care for 4.9 ± 6.8 (mean ± SD) intubated adult patients per month for varying durations (39.2% for 1–2 hours, 27.8% for 2–4 hours, and 22.7% for ≤1 hour). Combining all clinical scenarios, propofol was the most frequently used medication for post-ETI sedation (38.0% of all responses) and was the most frequently used agent except for the post-cardiac arrest, polytrauma, and hypercapnic respiratory failure scenarios. Ketamine was used second most frequently (28.2%), with midazolam being third most common (14.5%). Post-ETI sedation was provided by &gt; 98% of physicians in all situations except the post-cardiac arrest (26.1% indicating no sedation) and toxicology (15.5% indicating no sedation) scenarios. Sedation was provided by infusion in 74.6% of cases and bolus in 25.4%. Conclusion: Significant practice variability with respect to post-ETI sedation exists amongst Canadian emergency physicians. Future quality improvement studies should examine sedation provided in real clinical scenarios with a goal of establishing best sedation practices to improve patient safety and quality of care.


2020 ◽  
Vol 38 (3) ◽  
pp. 466-470
Author(s):  
Olga Lembersky ◽  
Dustin Golz ◽  
Casey Kramer ◽  
Andrea Fantegrossi ◽  
Jestin N. Carlson ◽  
...  

2019 ◽  
Vol 34 (6) ◽  
pp. 624-624
Author(s):  
Kelly Howe ◽  
Bryan Imhoff ◽  
Sam Wagner

2015 ◽  
Vol 66 (4) ◽  
pp. S100-S101
Author(s):  
N. Wong ◽  
C. Tainter ◽  
J. Lee ◽  
R. Strayer ◽  
J. Scofi ◽  
...  

PLoS ONE ◽  
2019 ◽  
Vol 14 (2) ◽  
pp. e0212170 ◽  
Author(s):  
Akihiko Inoue ◽  
Hiroshi Okamoto ◽  
Toru Hifumi ◽  
Tadahiro Goto ◽  
Yusuke Hagiwara ◽  
...  

2014 ◽  
Vol 15 (6) ◽  
pp. 708-711 ◽  
Author(s):  
Rahul Bhat ◽  
Munish Goyal ◽  
Shannon Graf ◽  
Anu Bhooshan ◽  
Eshetu Teferra ◽  
...  

2021 ◽  
Vol 22 (4) ◽  
pp. 827-833
Author(s):  
Bryan Imhoff ◽  
Samuel Wagner ◽  
Kelly Howe ◽  
Jonathan Dangers ◽  
Niaman Nazir

Introduction: Intubation and mechanical ventilation are common interventions performed in the emergency department (ED). These interventions cause pain and discomfort to patients and necessitate analgesia and sedation. Recent trends in the ED and intensive care unit focus on an analgesia-first model to improve patient outcomes. Initial data from our institution demonstrated an over-emphasis on sedation and an opportunity to improve analgesic administration. As a result of these findings, the ED undertook a quality improvement (QI) project aimed at improving analgesia administration and time to analgesia post-intubation. Methods: We performed a pre-post study between January 2017–February 2019 in the ED. Patients over the age of 18 who were intubated using rapid sequence intubation (RSI) were included in the study. The primary outcome was the rate of analgesia administration; a secondary outcome was time to analgesia administration. Quality improvement interventions occurred in two phases: an initial intervention focused on nursing education only, and a subsequent intervention that included nursing and physician education. Results: During the study period, 460 patients were intubated in the ED and met inclusion/exclusion criteria. Prior to the first intervention, the average rate of analgesia administration was 57.3%; after the second intervention, the rate was 94.9% (P <0.01). Prior to the first intervention, average time to analgesia administration was 36.0 minutes; after the second intervention, the time was 16.6 minutes (P value <0.01). Conclusion: This QI intervention demonstrates the ability of education interventions alone to increase the rate of analgesia administration and reduce the time to analgesia in post-intubation patients.


2012 ◽  
Vol 30 (11) ◽  
pp. 893-895 ◽  
Author(s):  
John M Watt ◽  
Albert Amini ◽  
Brittany R Traylor ◽  
Richard Amini ◽  
John C Sakles ◽  
...  

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