Impact of Acute Exacerbations on the Natural History of Chronic Obstructive Pulmonary Disease

2005 ◽  
Vol 12 (Supplement) ◽  
pp. S16-S18 ◽  
Author(s):  
Sanjay Sethi ◽  
Douglas B. Schwartz
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Natural History ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Acute Exacerbations ◽  
History Of

scholarly journals [Acute exacerbations in Chronic Obstructive Pulmonary Disease (COPD)]

2017 ◽  
Vol 11 (2) ◽  
Author(s):  
Domenico Lorenzo Urso
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Bacterial Infections ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Systemic Corticosteroids ◽  
Acute Exacerbations ◽  
History Of ◽  
Long Acting ◽  
Β2 Agonists

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. Acute exacerbations of COPD (AECOPD) are important events in the natural history of this condition because they negatively impact health status, rate of hospitalization, disease progression, and mortality.Viral and/or bacterial infections are the main cause of exacerbations. The treatments include systemic corticosteroids, bronchodilators, anticholinergics and/or short- or long-acting β2-agonists, and antibiotics in case of bacterial infections. In some cases, oxygen-therapy is indicated.This article focuses on several aspects of AECOPD, including epidemiology, diagnostic approach, i.e. investigations and management of AECOPD.

scholarly journals Natural history of COPD: gaps and opportunities

2017 ◽  
Vol 3 (4) ◽  
pp. 00117-2017 ◽  
Author(s):  
Alvar Agustí ◽  
Bartolomé Celli
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Smoking Cessation ◽  
Natural History ◽  
Disease Prevention ◽  
Lung Disease ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Prevention And Treatment ◽  
History Of

Understanding the natural history of a disease is as important as knowing its cause(s) for effective disease prevention and treatment. Yet, our current understanding of the natural history of chronic obstructive pulmonary disease (COPD) is incomplete and often controversial. This article discusses the current gaps, and hence opportunities for research, in this field. In particular, it discusses the following six specific questions. 1) Is COPD a “single” disease? 2) Is COPD “only” a lung disease? 3) When does COPD begin or what is “early” COPD? 4) How does COPD “progress”? 5) How do we assess disease “severity”? 6) Can COPD be prevented (beyond smoking cessation) or its course be modified once detected?

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