Acute and Long-term Excess Mortality After Polychlorinated Biphenyls and Polychlorinated Dibenzofurans Mixed Exposure From Contaminated Rice Oil: Yusho

Epidemiology ◽  
2011 ◽  
Vol 22 ◽  
pp. S239
Author(s):  
Saori Kashima ◽  
Takashi Yorifuji ◽  
Toshihide Tsuda
Keyword(s):  
Polychlorinated Biphenyls ◽  
Excess Mortality ◽  
Polychlorinated Dibenzofurans ◽  
Mixed Exposure ◽  
Rice Oil

scholarly journals Effect of prenatal exposure to polychlorinated biphenyls on cognitive development in children: A longitudinal study in Taiwan

2001 ◽  
Vol 178 (S40) ◽  
pp. s49-s52 ◽  
Author(s):  
T. J. Lai ◽  
Y. L. Guo ◽  
N. W. Guo ◽  
C. C. Hsu
Keyword(s):  
Cognitive Development ◽  
Polychlorinated Biphenyls ◽  
Prenatal Exposure ◽  
Infant Development ◽  
Matched Control ◽  
Degradation Products ◽  
Prenatally Exposed ◽  
Accidental Ingestion ◽  
Rice Oil

BackgroundFrom 1978 to 1979, a group of people in Taiwan were exposed to high levels of heat-degraded polychlorinated biphenyls (PCBs) owing to accidental ingestion of contaminated rice oil. Children born to mothers following the exposure (‘Yucheng’ children) were known to have hyperpigmented skin and other dysmorphology after birth.AimsTo determine the effect of prenatal exposure to PCBs on cognitive development in Yucheng children.MethodOne hundred and eighteen Yucheng children prenatally exposed to PCBs and degradation products, and community-matched control children who were exposed to background levels only, were followed from 1985 to 1998. The Bayley Scale for Infant Development, Chinese version of the Stanford – Binet IQTest, Raven's Coloured Progressive Matrices and Raven's Standardised Progressive Matrices were used to assess the cognitive development of these children.ResultsThe Yucheng children scored lower than control children on each of these methods of measurement between the ages of 2 and 12 years.ConclusionsPrenatal exposure to PCBs and their derivatives has long-term adverse effects on cognitive development in humans.

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