[PP.38.01] THE RELATIONSHIP BETWEEN REGULAR PHYSICAL EXERCISE AND NOCTURNAL BLOOD PRESSURE IN KOREAN AMBULATORY BLOOD PRESSURE MONITORING (KORABP) STUDY

2016 ◽  
Vol 34 ◽  
pp. e349
Author(s):  
B. Kim ◽  
J. Shin ◽  
Y. Lim ◽  
S. Kim
Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Bae Keun Kim ◽  
Lee Yonggu ◽  
Lim Young-Hyo ◽  
Jinho Shin

Introduction: There have been many reports showing that regular physical exercise can reduce the blood pressure (BP). Thus physical exercise is one of the important components of lifestyle modification of hypertension. It is known that nocturnal BP is an independent factor for the cardiovascular event but there are few studies for the relationship between physical exercise and nocturnal BP. Hypothesis: Hypothesized regular physical exercise reduced nocturnal BP, therefore, we aimed to analyze the relationship between regular physical exercise assessed by a questionnaire (7-day physical activity recall) and nocturnal BP in the general population. Methods: Among 4145 subjects whose data for both clinical data and ambulatory blood pressure monitoring (ABPM) data file from the 5308 Korean ABPM (KorABP) study subjects, 3689 subjects were analyzed. The exclusion criteria was age less than 20 years (n=84), missing data for the questionnaire for physical exercise (n=372). Physical exercise was defined as regular structured exercise which intensity was heavier than the fast walking for 30 minutes. The count was recorded as the number per week. Results: Age was 55.5 ± 14.1 years and female was 45.9 %. Prevalence of hypertension, antihypertensive medication (AHM), diabetes and cardiovascular diseases were 58.9%, 32.5%, 13.0%, and 21.1%, respectively. Daytime and nighttime systolic BP was 138.5 ± 17.2 mmHg and 126.3 ± 18.8 mmHg. When adjusted for age, sex, BMI, and AHM, exercise frequency was independently decreased daytime systolic BP (β = -0.52 mmHg per ex-ercise, p = 0.02). For the nighttime systolic BP further adjusted by daytime systolic BP and sleep quality, ex-ercise frequency was an independent factor (β = -0.26 mmHg per exercise, p = 0.002). The statistical significances were observed even for only for 1 times per week. When further adjusted by smoking, exercise frequency was in-dependent for nocturnal dipping (β = 0.18% per exercise, p = 0.015). Conclusions: Regular physical exercise is independently associated with lower nocturnal BP also lower daytime BP and with increased nocturnal dipping, which was independent of AHM status.


Hypertension ◽  
2020 ◽  
Vol 76 (Suppl_1) ◽  
Author(s):  
Robin A Felder ◽  
Katherine Schiermeyer ◽  
Mahabuba Akhter ◽  
Peng Xu ◽  
Wei Yue ◽  
...  

Ambulatory blood pressure monitoring is more useful for the diagnosis of various forms of hypertension including white coat and morning surge as well as other conditions that are associated with increased morbidity and mortality such as sleep apnea. Nocturnal changes in blood pressure (BP) can also aid in the diagnosis of various manifestations of blood pressure independent of hypertension known as salt sensitivity (SS) and inverse salt sensitivity (ISS) of blood pressure. SS individuals experience an increase in BP on a high salt diet while ISS individuals experience a paradoxical increase in BP on a low salt diet. SS and ISS phenotypes affect approximately 18% and 15% of normotensives, respectively, which may result in significant morbidity and mortality similar to untreated hypertension. Consuming a personally appropriate salt diet can result in a circadian drop in BP during sleep, and failure to “dip” can lead to significant cardiovascular diseases. Nocturnal dipping is usually recorded using an ambulatory blood pressure monitoring (ABPM) device. Arterial pulse wave measurements using oscillatory photoplethysmography (OP) are minimally invasive when compared to an inflatable cuff, which can disturb sleep and raise blood pressure. We measured nocturnal blood pressure using a ring based photoplethysmograph (SensoGram Technologies, Plano Texas). A UVA Salt Study participant wore their device upon going to bed and then uploaded nocturnal data to the internet each morning. Systolic and diastolic BP is capable of being measured 30 times a minute for approximately 9 hours and providing over 5000 data points each night. Three representative dipping profiles for an individual yielded a dipping reduction of 24% ± 3% for systolic and 40% ± 10% for diastolic (1 - mid-sleeping lowest value/start of evening highest value). This additional data afforded by nocturnal BP measurement is anticipated to improve diagnostic opportunities in the measurement of SS and ISS phenotypes and provide the user with reassurance that nocturnal BP dipping is occurring.


2021 ◽  
Author(s):  
Ming Fu ◽  
Xiangming Hu ◽  
Shixin Yi ◽  
Shuo Sun ◽  
Ying Zhang ◽  
...  

Abstract Masked hypertension (MHT), as an independent clinical entity, its subclinical cardiac dysfunction can be early detected by left ventricular global longitudinal strain (GLS). Yet the relationship between MHT and GLS is still unclear. Therefore, we tried to conduct a community-based cross-sectional study to define this relationship. A total of 308 consecutively enrolled participants from Dongguan, China, were divided into non-hypertension (NHT) and MHT groups. Baseline characteristics were recorded, and 2-dimentional speckle-tracking echocardiography and 24-hour ambulatory blood pressure monitoring were performed. Univariate and multivariate linear regression analyses were used to assess the associations between MHT and GLS, and the dose–response curve was plotted to demonstrate their relationship. The mean age of the NHT and MHT groups was 57 and 59 years, respectively. Signs of left ventricular diastolic function, E/A (1.01 ± 0.26 vs 0.86 ± 0.23, P < 0.001) and E/e’ (8.58 ± 2.02 vs 11.70 ± 3.37, P < 0.001) were reduced in the MHT group while those of the NHT group were nearly normal. The MHT group also showed a significantly lower (‘worse’) GLS than NHT (-15.79% ± 2.81% vs -19.62% ± 1.67% vs , P < 0.001) while left ventricular ejection fraction (LVEF) did not differ between the groups. Worse GLS was independently and significantly associated with MHT both in univariate (odds ratio [OR]: 1.97, P < 0.001) and stepwise multivariate regression analysis (OR: 1.99, P < 0.001). Further analysis showed adjusted nonlinear correlation between MHT and GLS. Our study described the relationship between MHT and GLS and concluded that -14% of GLS as the cut-off value reflected MHT-associated myocardial injury before LVEF decreases.


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