scholarly journals P0731 / #2140: SARS-COV-2-RELATED MULTISYSTEM INFLAMMATORY SYNDROME IN FAMILIAL REFRACTORY HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS: A CASE REPORT

2021 ◽  
Vol 22 (Supplement 1 3S) ◽  
pp. 352-352
Author(s):  
L.A. Luna Santiago ◽  
N. Aguilar-Martínez ◽  
B. Cabañas-Espinosa ◽  
X. Ramírez-Machuca
2019 ◽  
Vol 12 (8) ◽  
pp. e230255
Author(s):  
Pawan Kumar Singh ◽  
Rakesh Kodati ◽  
Manish Rohilla ◽  
Prashant Sharma

Hemophagocytic lymphohistiocytosis (HLH) is an inflammatory syndrome characterised by unregulated macrophage and T-lymphocyte activation, resulting in cytokine overproduction and subsequent histiocytic phagocytosis. Here we report a case of pulmonary cryptococcosis, in a 59-year-old diabetic patient, with no other risk factors whose clinical course was complicated by secondary hemophagocytosis. Even after addressing the primary underlying illness (pulmonary cryptococcosis), his clinical condition continued to worsen. After excluding the other causes of HLH and possible reasons of his clinical worsening, glucocorticoids were added following which the patient experienced a remarkable improvement in his clinical and laboratory parameters. To our knowledge, this is the first case report of HLH being caused by pulmonary cryptococcosis and only second case report of cryptococcosis being complicated with HLH (previous report being associated with meningoencephalitic cryptococcosis).


2021 ◽  
Vol 9 (8) ◽  
Author(s):  
Mounia Bendari ◽  
Hanane Delsa ◽  
Nouama Bouanani ◽  
Rajaa Jabouri ◽  
Safaa Darouich ◽  
...  

Author(s):  
Aleksandra Opalińska ◽  
Dominika Kwiatkowska ◽  
Adrian Burdacki ◽  
Mirosław Markiewicz ◽  
Dominik Samotij ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Samin Alavi ◽  
Maryam Ebadi ◽  
Alireza Jenabzadeh ◽  
M. T. Arzanian ◽  
Sh. Shamsian

Herein, the first case of childhood erythrophagocytosis following chemotherapy for erythroleukemia in a child with monosomy 7 is reported. A 5-year-old boy presented with anemia, thrombocytopenia, and hepatosplenomegaly in whom erythroleukemia was diagnosed. Prolonged pancytopenia accompanied by persistent fever and huge splenomegaly and hepatomegaly became evident after 2 courses of chemotherapy. On bone marrow aspiration, macrophages phagocytosing erythroid precursors were observed and the diagnosis of HLH was established; additionally, monosomy 7 was detected on bone marrow cytogenetic examination. In conclusion, monosomy 7 can lead to erythrophagocytosis associated with erythroid leukemia and should be considered among the chromosomal abnormalities contributing to the association.


2021 ◽  
Vol 12 ◽  
pp. 100092
Author(s):  
Craig E McCrossan ◽  
Luke Mair ◽  
Helena Parsons ◽  
Rachel S Tattersall ◽  
Kumar K Basu

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