scholarly journals Neuropsychiatric Outcomes in UK Military Veterans With Mild Traumatic Brain Injury and Vestibular Dysfunction

2020 ◽  
Vol 35 (1) ◽  
pp. 57-65 ◽  
Author(s):  
Emma Denby ◽  
Dominic Murphy ◽  
Walter Busuttil ◽  
Mohamed Sakel ◽  
David Wilkinson
2018 ◽  
Vol 34 (5) ◽  
pp. 706-712 ◽  
Author(s):  
Victoria C Merritt ◽  
Kristina M Lapira ◽  
Alexandra L Clark ◽  
Scott F Sorg ◽  
Madeleine L Werhane ◽  
...  

Abstract Objective We evaluated the influence of the APOE-ε4 allele on post-concussive symptoms in military Veterans with a remote history of mild traumatic brain injury (mTBI). Method Participants (N = 77) were administered neuropsychiatric measures, on average, approximately 5 years following their most recent mTBI and provided a DNA sample for APOE genotyping. Veterans were divided into two groups based on their ε4 status (n = 14 ε4+, n = 63 ε4–). The Neurobehavioral Symptom Inventory (NSI) was the primary outcome measure, from which a total score was derived, as well as three symptom clusters (somatic, cognitive, and affective). Results ANCOVAs showed a significant main effect of ε4 genotype on the NSI total score and somatic symptom cluster after adjusting for posttraumatic stress symptoms and mTBI history (p = .019–.028, ηp2 = .064–.073), such that ε4+ Veterans endorsed significantly greater symptoms than ε4– Veterans. Conclusions Our findings suggest that genetic risk may help to explain the poorer long-term outcomes often observed in this population.


2018 ◽  
Vol 31 (1) ◽  
pp. 114-124 ◽  
Author(s):  
Craig A. Marquardt ◽  
Daniel J. Goldman ◽  
Bruce N. Cuthbert ◽  
Shmuel Lissek ◽  
Scott R. Sponheim

Brain Injury ◽  
2016 ◽  
Vol 30 (12) ◽  
pp. 1491-1500 ◽  
Author(s):  
Nicholas D. Davenport ◽  
Greg J. Lamberty ◽  
Nathaniel W. Nelson ◽  
Kelvin O. Lim ◽  
Michael T. Armstrong ◽  
...  

2018 ◽  
Vol 75 (9) ◽  
pp. 1055 ◽  
Author(s):  
Deborah E. Barnes ◽  
Amy L. Byers ◽  
Raquel C. Gardner ◽  
Karen H. Seal ◽  
W. John Boscardin ◽  
...  

2018 ◽  
Vol 27 (1S) ◽  
pp. 485-494
Author(s):  
Karen Gallagher ◽  
Tamiko Azuma

Purpose The purpose of this study was to determine whether detailed analysis of story recall performance reveals significant differences between veterans with and without history of mild traumatic brain injury (mTBI). Method Twenty-one military veterans participated, with 7 reporting history of mTBI. All participants were administered the Logical Memory I and II subtests from the Wechsler Memory Scale–Fourth Edition (Wechsler, 2009). Responses were scored for total correct ideas (TCI) and total words produced (TWP). Results Although the groups did not differ in scaled scores, other measures did reveal significant differences. After a delay, the mTBI group showed a greater drop in TCI relative to the control group. Additionally, the control group showed an increase in TWP when the recall was delayed versus immediate; a pattern not observed for the mTBI group. Conclusions The mTBI and control groups did not significantly differ in scaled scores. However, group differences were observed in TCI and TWP. The findings suggest that, relative to the control group, the mTBI group were less successful in retrieving episodic information and eliciting self-cueing. Small sample size limited data interpretation, and larger sample sizes are needed to confirm the findings. The results indicate that veterans with mTBI may present with symptoms persisting beyond the acute state of the injury.


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