Nivolumab-Induced Harada-like Uveitis with Bacillary Detachment Mimicking Choroidal Metastasis

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Caleb C Ng ◽  
Joshua C Ng ◽  
Robert N Johnson ◽  
H. Richard McDonald ◽  
Anita Agarwal
Keyword(s):  
Author(s):  
Victor Duque ◽  
Carolina de la Pinta ◽  
Ciriaco Corral ◽  
Carmen Vallejo ◽  
Margarita Martin ◽  
...  

Abstract Introduction: Choroidal metastases are the most frequent intraocular secondary tumours, with a prevalence of 2–7% according to the literature. Our aim was to review a clinical case of choroidal metastasis. We present a case of a 63-year-old male patient diagnosed in 2018 with lung adenocarcinoma cT4N0M1. The patient had three metastases in the brain, which were successfully treated with radiosurgery (RS). The patient was treated with chemotherapy with pemetrexed–cisplatin schedule. Five months after diagnosis, the patient presented with decreased vision in the right eye. After ophthalmologic evaluation, he was diagnosed with a right choroidal metastasis, which was treated with external beam radiotherapy with 20 Gy in five fractions, resulting in improved visual acuity and a complete clinical and radiological response. The patient took part in a clinical trial that continued with systemic chemotherapy. Twenty-two months after radiotherapy to the eye, the patient has good visual acuity without any side effects. Conclusions: Choroidal metastasis treated with radiotherapy achieves good local control, with limited side effects, allowing an improvement in visual acuity and consequently, an improvement in the patient´s quality of life.


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pp. 496-498 ◽  
Author(s):  
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Kuo-Sheng Fan ◽  
Yen-Hsien Lee ◽  
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Wen-Hsiung Fan

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pp. 144-148
Author(s):  
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Vol 43 (7) ◽  
pp. 746-751 ◽  
Author(s):  
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Yasuhisa Abe ◽  
Shin-ichi Sasagawa ◽  
Hiroyuki Hanada ◽  
Yuko Hatori ◽  
...  

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