scholarly journals Diagnostic Accuracy of the Xpert MTB/RIF Assay for Extrapulmonary Tuberculosis in Children With Musculoskeletal Infections

2016 ◽  
Vol 35 (11) ◽  
pp. 1165-1168 ◽  
Author(s):  
Michael Held ◽  
Maritz Laubscher ◽  
Stewart Mears ◽  
Stewart Dix-Peek ◽  
Lesley Workman ◽  
...  
Author(s):  
Lev Borisovich Shlopak

Miliary tuberculosis is a special form of the disease with a hematogenous transmission route and multiple lesions of internal organs in the form of tiny tubercles resembling millet grains. This infectious disease is one of the forms of disseminated tuberculous lesion, it has a hematogenous transmission route and develops against the background of mycobacteremia. Miliary tuberculosis accounts for about 2 % of all cases and about 20 % of cases of extrapulmonary tuberculosis. In children, miliary tuberculosis most often manifests itself against the background of the primary pulmonary process immediately after infection, in adults, as a rule, this form of tuberculosis lesion develops from the reactivation of hematogenous dissemination. Serous membranes, lungs, lymph nodes, kidneys and bones are most often affected. With this form of the disease, the primary stage of lymphogenous lesion is most often absent, and diagnosis presents significant difficulties due to the absence of specific symptoms and a blurred clinical picture of the disease. Against the background of difficulties in diagnosis, very often, treatment measures begin quite late, which can lead to the development of neglected cases and cause death.


2005 ◽  
Vol 6 (1) ◽  
pp. 52-54 ◽  
Author(s):  
Batool Sharifi-Mood . ◽  
Manijeh Khalili . ◽  
Malihe Metanat . ◽  
Masoud Salehi .

2001 ◽  
Vol 41 (3) ◽  
pp. 155
Author(s):  
Heda Melinda Nataprawira ◽  
Henny Komalia

Abdominal tuberculosis is one of the extrapulmonary tuberculosis commonly found in adolescens, however, due to its non-specific and vague abdominal symptoms, it is rarely found and reported in children. To evaluate abdominaltuberculosis in children from clinical point of view, we conducted a 5-year retrospective study on children hospitalized over a period of 1995 to 1999 in Hasan Sadikin Hospital-Bandung. Of the 15 children diagnosed as having abdominal tuberculosis, 10 (66.7%) were female and 5 (33,3%) male, age ranged from 14 – 162 months and most of them were > 10 years of age.On admission, abdominal distention was the most common complaint found (60.0%), followed by dyspnoe 3 (20.0%), abdominal pain 2 (13.3%) and generalized oedem 1 (6.7%). Most of the children (93.3%) were undernourished which half of them were severely undernourished. Seven children showed positive Mantoux testing with PPD 5 TU. There was familyhistory of adults TB discovered in 9 (60%) of the children. Eighty-percent had BCG vaccination and 6 (50%) of the showed positive scarr. Chest X-ray showed pulmonal and/or pleural involvement in 13 of the 15 children (86.7%). All ascitic fluid taken from 9 patients showed increased protein level and lymphocyte predominance. Histopathologic examinations of 5 childrensupported the diagnosis. There was no positive results of acid fast bacilli and culture done for Mycobacterium tuberculosis in gastric aspirate as well as ascitic fuid. Peritonitis tuberculosis was most commonly diagnosed (80.0%), followed by mesenterial/nodal tuberculosis (20.0%). All of the children followed (60.0%) responded well to the drugs therapy.


2018 ◽  
Vol 36 (3) ◽  
pp. 357-363 ◽  
Author(s):  
Sheetal Bankar ◽  
Reena Set ◽  
Disha Sharma ◽  
Daksha Shah ◽  
Jayanthi Shastri

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