Features of the diagnosis of miliary forms of tuberculosis

Author(s):  
Lev Borisovich Shlopak

Miliary tuberculosis is a special form of the disease with a hematogenous transmission route and multiple lesions of internal organs in the form of tiny tubercles resembling millet grains. This infectious disease is one of the forms of disseminated tuberculous lesion, it has a hematogenous transmission route and develops against the background of mycobacteremia. Miliary tuberculosis accounts for about 2 % of all cases and about 20 % of cases of extrapulmonary tuberculosis. In children, miliary tuberculosis most often manifests itself against the background of the primary pulmonary process immediately after infection, in adults, as a rule, this form of tuberculosis lesion develops from the reactivation of hematogenous dissemination. Serous membranes, lungs, lymph nodes, kidneys and bones are most often affected. With this form of the disease, the primary stage of lymphogenous lesion is most often absent, and diagnosis presents significant difficulties due to the absence of specific symptoms and a blurred clinical picture of the disease. Against the background of difficulties in diagnosis, very often, treatment measures begin quite late, which can lead to the development of neglected cases and cause death.

2011 ◽  
Vol 5 (2) ◽  
pp. 97-99 ◽  
Author(s):  
Parul Goel ◽  
Veena Gupta ◽  
Anjali Narwal ◽  
Jigyasa Duhan

ABSTRACT Actinomycosis is an infectious disease characterized by chronic granulomatous and suppurative lesions often caused by Actinomyces group. Actinomycosis has been referred to as the chameleon of head and neck pathology because of its varied clinical picture which can resemble various pathologies ranging from benign infection to metastatic tumour. Nowadays, the diagnosis of the same may be difficult because the number of patients with typical symptoms has decreased, and there is a low success rate in culturing the microorganism. Mandibular osteomyelitis is also underappreciated by many clinicians in their assessment of head and neck infections. Most cases are traced to an odontogenic source, with periapical tooth abscess and posttraumatic or surgical complication as key antecedent events. A case of osteomyelitis of mandible initiated from a vital but peridontally compromised tooth is reported. Radiography of this case revealed bone destruction, and H & E of the biopsied tissue showed branching filaments resembling ray fungus.


Author(s):  
Olga Alekseevna Petrishcheva

Systemic scleroderma is a chronic disease, the etiology of which is not fully understood. In systemic scleroderma, there is a diffuse change in the skin with the development of fibrosis, as well as with damage to internal organs (in particular, the esophagus, lower gastrointestinal tract, heart, liver and kidneys). The disease can proceed in a generalized and focal form; it is also possible to develop a variant of scleroderma without affecting the skin. A typical clinical picture of the disease is characterized by damage to the skin, the occurrence of multiple joint damage, the development of dysphagia, and the appearance of heartburn, general swelling and the formation of digital contractures. In women, the disease occurs 4 times more often than in men, while it is very rare in children. The onset of the disease is usually observed between the ages of 30 and 50. The diagnosis is established on the basis of the clinical picture, taking into account laboratory data. There is no specific treatment; therapeutic measures are usually aimed at combating complications.


2005 ◽  
Vol 6 (1) ◽  
pp. 52-54 ◽  
Author(s):  
Batool Sharifi-Mood . ◽  
Manijeh Khalili . ◽  
Malihe Metanat . ◽  
Masoud Salehi .

2001 ◽  
Vol 41 (3) ◽  
pp. 155
Author(s):  
Heda Melinda Nataprawira ◽  
Henny Komalia

Abdominal tuberculosis is one of the extrapulmonary tuberculosis commonly found in adolescens, however, due to its non-specific and vague abdominal symptoms, it is rarely found and reported in children. To evaluate abdominaltuberculosis in children from clinical point of view, we conducted a 5-year retrospective study on children hospitalized over a period of 1995 to 1999 in Hasan Sadikin Hospital-Bandung. Of the 15 children diagnosed as having abdominal tuberculosis, 10 (66.7%) were female and 5 (33,3%) male, age ranged from 14 – 162 months and most of them were > 10 years of age.On admission, abdominal distention was the most common complaint found (60.0%), followed by dyspnoe 3 (20.0%), abdominal pain 2 (13.3%) and generalized oedem 1 (6.7%). Most of the children (93.3%) were undernourished which half of them were severely undernourished. Seven children showed positive Mantoux testing with PPD 5 TU. There was familyhistory of adults TB discovered in 9 (60%) of the children. Eighty-percent had BCG vaccination and 6 (50%) of the showed positive scarr. Chest X-ray showed pulmonal and/or pleural involvement in 13 of the 15 children (86.7%). All ascitic fluid taken from 9 patients showed increased protein level and lymphocyte predominance. Histopathologic examinations of 5 childrensupported the diagnosis. There was no positive results of acid fast bacilli and culture done for Mycobacterium tuberculosis in gastric aspirate as well as ascitic fuid. Peritonitis tuberculosis was most commonly diagnosed (80.0%), followed by mesenterial/nodal tuberculosis (20.0%). All of the children followed (60.0%) responded well to the drugs therapy.


2016 ◽  
Vol 35 (11) ◽  
pp. 1165-1168 ◽  
Author(s):  
Michael Held ◽  
Maritz Laubscher ◽  
Stewart Mears ◽  
Stewart Dix-Peek ◽  
Lesley Workman ◽  
...  

2007 ◽  
Vol 60 (3-4) ◽  
pp. 140-144
Author(s):  
Ljiljana Nesic ◽  
Zoran Todorovic ◽  
Olgica Gajovic ◽  
Predrag Canovic

Introduction. Acute viral encephalitis is an infectious disease, which is characterized by sudden onset, serious clinical picture and with an uncertain outcome. Disturbances of consciousness are common in the course of acute viral encephalitis. Consciousness is the highest form of psychic life and consciousness disturbances may include quantitative (somnolentia, sopor, coma) and qualitative symptoms (convulsions, twilight state). Material and methods. We investigated 63 patients with acute viral encephalitis. The youngest patient was 15, and the oldest one 69 years of age. We examined the state of consciousness in all patients. Results Of all examined patients, 54 (85.72%) patients had disturbances of consciousness, 9 (14.25%) patients had no consciousness disturbances, 11 (17.46%) patients had sopor and 24 (38.09%) patients were in coma. The highest percentage of lethal outcomes was recorded in coma patients (12.5%). The longer the duration of consciousness disturbances, the higher the mortality among these patients. Discussion Subjective and objective factors cause different grades and duration of consciousness disturbances. The highest percentage of patients who recovered without consequences was established in the group of patients (81.82%) with somnolence. The highest percentage of patients who recovered with consequences (20.8%) and patients (12.5%) with lethal outcome was recorded in the group of patients in coma. These findings are in correlation with literature data. .


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